iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069837

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01123556

Gene Name

KDM2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000016168.2	ENSNLET00000020597.2	ENSNLEP00000019607.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	1.00e-05	25.6	885	976
E3 activity/RING/PHD	8.80e-15	54.6	569	634

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 54   asrr.tprqpprgpsaaakpkaglrseaaaapap.apaptptpeegpdaglldrlpeeilveilklldkeellraarvcrrwqelasqk 140
            s r  pr   r p + + pk+         p p +p p   p    d g  + +  e+++ ++++l++++l+ + rvcr+w++ + +k
   Q: 885  PSLRsPPRVISRPPPSVSPPKCMQMERHVIRPPPiSPPPDSLP---LDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDK 970
           4444146777888888888887665555555555133344444...36677888899**************************555559 PP
   S: 141  alwktv 146
           +lw ++
   Q: 971  RLWTRI 976
           999876 PP

E3 activity/RING/PHD

   S: 2    kvClvCgeggede.....k.....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrsk 54
           +vClvCge+g+++     +     +l+eC++C+e++Hp+Clk++     v++elpn+  w+CpkC+++
   Q: 569  AVCLVCGEAGKEDtveeeEgkfnlMLMECSICNEIIHPGCLKIKesegvVNDELPNC--WECPKCNHA 634
           79*********9977765156789*********************************..*******85 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

FNYEYVQREA LRVPLIFREK DGLGIKMPDP DFTVRDVKLL VGSRRLVDVM DVNTQKGTEM 60
SMSQFVRYYE TPEAQRDKLY NVISLEFSHT KLEHLVKRPT VVDLVDWVDN MWPQHLKEKQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTCAACTA TGAGTACGTA CAGAGAGAAG CTCTCAGGGT TCCCCTGATA TTTCGAGAAA 60
AGGATGGACT GGGAATTAAG TAAGTTGCTG AAACTAATCG CTCCTTCCCC CGTCTTCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF02373--JmjC
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0031519--C:PcG protein complex
GO:0003677--F:DNA binding
GO:0008270--F:zinc ion binding
GO:0035518--P:histone H2A monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	92.71	0.00e+00	2022.00
IUUC-Apl-003787	Anas platyrhynchos	86.19	0.00e+00	1820.00
IUUC-Aca-004247	Anolis carolinensis	77.21	0.00e+00	1608.00
IUUC-Bta-013531	Bos taurus	93.02	0.00e+00	2054.00
IUUC-Cel-018303	Caenorhabditis elegans	46.10	5.00e-79	289.00
IUUC-Cja-018876	Callithrix jacchus	91.29	0.00e+00	2001.00
IUUC-Cfa-020857	Canis familiaris	93.36	0.00e+00	2059.00
IUUC-Cpo-021967	Cavia porcellus	90.39	0.00e+00	1863.00
IUUC-Csa-023210	Chlorocebus sabaeus	96.20	0.00e+00	2078.00
IUUC-Dre-028272	Danio rerio	63.79	0.00e+00	1362.00
IUUC-Dno-030034	Dasypus novemcinctus	90.83	0.00e+00	1968.00
IUUC-Dor-030736	Dipodomys ordii	80.93	0.00e+00	961.00
IUUC-Eca-034255	Equus caballus	94.10	0.00e+00	2070.00
IUUC-Eeu-035038	Erinaceus europaeus	91.33	0.00e+00	1026.00
IUUC-Fca-035786	Felis catus	93.10	0.00e+00	2048.00
IUUC-Fal-037589	Ficedula albicollis	85.89	0.00e+00	1853.00
IUUC-Gmo-038781	Gadus morhua	63.20	8.00e-177	614.00
IUUC-Gga-041103	Gallus gallus	87.44	0.00e+00	1065.00
IUUC-Gac-041304	Gasterosteus aculeatus	70.33	0.00e+00	941.00
IUUC-Ggo-044522	Gorilla gorilla	95.85	0.00e+00	1618.00
IUUC-Hsa-045877	Homo sapiens	96.46	0.00e+00	2075.00
IUUC-Itr-049003	Ictidomys tridecemlineatus	91.91	0.00e+00	1286.00
IUUC-Lch-049950	Latimeria chalumnae	81.32	0.00e+00	1735.00
IUUC-Loc-051972	Lepisosteus oculatus	70.64	0.00e+00	1030.00
IUUC-Laf-053623	Loxodonta africana	93.08	0.00e+00	1949.00
IUUC-Mcc-054943	Macaca mulatta	96.29	0.00e+00	2073.00
IUUC-Meu-056259	Macropus eugenii	86.55	0.00e+00	1871.00
IUUC-Mga-059671	Meleagris gallopavo	83.54	0.00e+00	1836.00
IUUC-Mmr-061003	Microcebus murinus	93.09	0.00e+00	2041.00
IUUC-Mmu-063584	Mus musculus	89.99	0.00e+00	1985.00
IUUC-Mpu-066056	Mustela putorius furo	93.19	0.00e+00	2026.00
IUUC-Mlu-067850	Myotis lucifugus	92.35	0.00e+00	2048.00
IUUC-Opr-070943	Ochotona princeps	89.11	0.00e+00	1882.00
IUUC-Ont-071663	Oreochromis niloticus	64.27	0.00e+00	1402.00
IUUC-Oan-072934	Ornithorhynchus anatinus	72.85	0.00e+00	1105.00
IUUC-Ocu-074706	Oryctolagus cuniculus	93.01	0.00e+00	2045.00
IUUC-Ola-086543	Oryzias latipes	62.49	0.00e+00	1379.00
IUUC-Oga-088671	Otolemur garnettii	84.07	0.00e+00	1002.00
IUUC-Oar-089560	Ovis aries	87.73	0.00e+00	1956.00
IUUC-Ptr-090875	Pan troglodytes	96.46	0.00e+00	2109.00
IUUC-Pan-091788	Papio anubis	92.17	0.00e+00	1995.00
IUUC-Psi-093382	Pelodiscus sinensis	86.07	0.00e+00	1849.00
IUUC-Pfo-096272	Poecilia formosa	65.80	0.00e+00	1352.00
IUUC-Pab-097907	Pongo abelii	91.48	0.00e+00	1924.00
IUUC-Pca-100628	Procavia capensis	83.16	0.00e+00	1733.00
IUUC-Pva-102956	Pteropus vampyrus	89.57	0.00e+00	1090.00
IUUC-Rno-105722	Rattus norvegicus	91.16	0.00e+00	1655.00
IUUC-Sha-106626	Sarcophilus harrisii	79.65	0.00e+00	1700.00
IUUC-Ssc-115918	Sus scrofa	91.73	0.00e+00	1722.00
IUUC-Tru-118638	Takifugu rubripes	70.04	0.00e+00	937.00
IUUC-Tbe-127654	Tupaia belangeri	75.36	0.00e+00	1508.00
IUUC-Ttr-128821	Tursiops truncatus	87.29	0.00e+00	1873.00
IUUC-Xtr-131823	Xenopus tropicalis	73.72	0.00e+00	1571.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence