iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089560

Ensembl Protein ID

ENSOARP00000014881.1

UniProt Accession

W5PWP8; W5PWP8_SHEEP

Genbank Protein ID

ENSOARP00000014881

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01039230

Gene Name

KDM2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000013863.1	ENSOART00000015101.1	ENSOARP00000014881.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.20e-14	54.4	641	706

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggede.....k.....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrsk 54
           +vClvCge+g+++     +     +l+eC++C+e++Hp+Clk++     v++elpn+  w+CpkC+++
   Q: 641  AVCLVCGEAGKEDtveeeEgkfnlMLMECSICNEIIHPGCLKIKesegvVNDELPNC--WECPKCNHA 706
           79*********9977765156789*********************************..*******85 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MEAEKDSGRR LRPIDRQRYD ENEDLSDVEE IVSARGFSLE EKLRSQLYQG DFVHAMEGKD 60
FNYEYVQREA LRVPLVFREK DGLGIKMPDP DFTVRDVKLL VGSRRLVDVM DVNTQKGTEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGCAG AGAAAGACTC TGGAAGAAGA TTGGTGTGTA GCTTTTTTTT TTTTTTCCAA 60
ATCTGTATCT GGTTTATGAT AGATCTATTT TTTTTGGTCG TTGTTTCTTG CTGCCTTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF02373--JmjC
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0031519--C:PcG protein complex
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0048596--P:embryonic camera-type eye morphogenesis
GO:0021592--P:fourth ventricle development
GO:0035518--P:histone H2A monoubiquitination
GO:0070544--P:histone H3-K36 demethylation
GO:0021993--P:initiation of neural tube closure
GO:0021670--P:lateral ventricle development
GO:0030901--P:midbrain development
GO:0021555--P:midbrain-hindbrain boundary morphogenesis
GO:2000178--P:negative regulation of neural precursor cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030307--P:positive regulation of cell growth
GO:1902459--P:positive regulation of stem cell population maintenance
GO:0007283--P:spermatogenesis
GO:0021678--P:third ventricle development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	92.29	0.00e+00	2242.00
IUUC-Apl-003787	Anas platyrhynchos	79.97	0.00e+00	1872.00
IUUC-Aca-004247	Anolis carolinensis	73.87	0.00e+00	1760.00
IUUC-Ame-011463	Astyanax mexicanus	75.21	3.00e-172	599.00
IUUC-Bta-013531	Bos taurus	94.54	0.00e+00	2323.00
IUUC-Cel-018303	Caenorhabditis elegans	44.86	6.00e-83	302.00
IUUC-Cja-018876	Callithrix jacchus	87.18	0.00e+00	2075.00
IUUC-Cfa-020857	Canis familiaris	92.80	0.00e+00	2284.00
IUUC-Cpo-021967	Cavia porcellus	88.78	0.00e+00	2092.00
IUUC-Csa-023210	Chlorocebus sabaeus	91.49	0.00e+00	2191.00
IUUC-Dre-028272	Danio rerio	62.28	0.00e+00	1508.00
IUUC-Dno-030034	Dasypus novemcinctus	89.41	0.00e+00	2165.00
IUUC-Dor-030736	Dipodomys ordii	77.58	0.00e+00	936.00
IUUC-Eca-034255	Equus caballus	92.45	0.00e+00	2175.00
IUUC-Eeu-035038	Erinaceus europaeus	95.03	0.00e+00	1165.00
IUUC-Fca-035786	Felis catus	92.95	0.00e+00	2245.00
IUUC-Fal-037589	Ficedula albicollis	79.38	0.00e+00	1969.00
IUUC-Gmo-038781	Gadus morhua	63.55	0.00e+00	684.00
IUUC-Gga-041103	Gallus gallus	79.67	0.00e+00	1099.00
IUUC-Gac-041304	Gasterosteus aculeatus	59.34	0.00e+00	1491.00
IUUC-Ggo-044522	Gorilla gorilla	88.92	0.00e+00	1644.00
IUUC-Hsa-045877	Homo sapiens	90.90	0.00e+00	2197.00
IUUC-Itr-049003	Ictidomys tridecemlineatus	88.75	0.00e+00	1258.00
IUUC-Lch-049950	Latimeria chalumnae	73.90	0.00e+00	1845.00
IUUC-Loc-051972	Lepisosteus oculatus	72.20	0.00e+00	1059.00
IUUC-Laf-053623	Loxodonta africana	90.44	0.00e+00	2142.00
IUUC-Mcc-054943	Macaca mulatta	91.58	0.00e+00	2191.00
IUUC-Meu-056259	Macropus eugenii	81.18	0.00e+00	1997.00
IUUC-Mga-059671	Meleagris gallopavo	80.27	0.00e+00	1917.00
IUUC-Mmr-061003	Microcebus murinus	91.50	0.00e+00	2248.00
IUUC-Mmu-063584	Mus musculus	90.14	0.00e+00	2190.00
IUUC-Mpu-066056	Mustela putorius furo	92.42	0.00e+00	2249.00
IUUC-Mlu-067850	Myotis lucifugus	91.90	0.00e+00	2229.00
IUUC-Nle-069837	Nomascus leucogenys	87.73	0.00e+00	1954.00
IUUC-Opr-070943	Ochotona princeps	87.64	0.00e+00	2070.00
IUUC-Ont-071663	Oreochromis niloticus	63.78	0.00e+00	1545.00
IUUC-Oan-072934	Ornithorhynchus anatinus	72.16	0.00e+00	1228.00
IUUC-Ocu-074706	Oryctolagus cuniculus	91.58	0.00e+00	2245.00
IUUC-Ola-086543	Oryzias latipes	61.25	0.00e+00	1521.00
IUUC-Oga-088671	Otolemur garnettii	91.74	0.00e+00	784.00
IUUC-Ptr-090875	Pan troglodytes	90.90	0.00e+00	2221.00
IUUC-Pan-091788	Papio anubis	88.85	0.00e+00	2134.00
IUUC-Psi-093382	Pelodiscus sinensis	79.70	0.00e+00	1970.00
IUUC-Pma-094687	Petromyzon marinus	55.96	3.00e-90	326.00
IUUC-Pfo-096272	Poecilia formosa	61.18	0.00e+00	1467.00
IUUC-Pab-097907	Pongo abelii	86.99	0.00e+00	2047.00
IUUC-Pca-100628	Procavia capensis	93.11	0.00e+00	1071.00
IUUC-Pva-102956	Pteropus vampyrus	88.40	0.00e+00	1150.00
IUUC-Rno-105722	Rattus norvegicus	88.82	0.00e+00	1753.00
IUUC-Sha-106626	Sarcophilus harrisii	79.89	0.00e+00	1797.00
IUUC-Smo-109024	Selaginella moellendorffii	39.47	6.00e-56	211.00
IUUC-Ssc-115918	Sus scrofa	91.43	0.00e+00	1708.00
IUUC-Tru-118638	Takifugu rubripes	65.93	0.00e+00	977.00
IUUC-Tsy-118820	Tarsius syrichta	87.37	0.00e+00	740.00
IUUC-Tbe-127654	Tupaia belangeri	75.83	0.00e+00	1634.00
IUUC-Ttr-128821	Tursiops truncatus	85.96	0.00e+00	2026.00
IUUC-Xtr-131823	Xenopus tropicalis	70.78	0.00e+00	1676.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence