iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-091788

Ensembl Protein ID

ENSPANP00000004785.1

UniProt Accession

A0A096MXZ4; A0A096MXZ4_PAPAN

Genbank Protein ID

ENSPANP00000004785

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01057349

Gene Name

KDM2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000010984.1	ENSPANT00000014643.1	ENSPANP00000004785.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.70e-09	37.8	633	695

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggede.....k.....slveCekCrewfHpaClkls.....veeelpnsekwiCpkC 51
           +vClvCge+g+++     +     +l+eC++C+e++Hp+Clk s      +++ p+s+    p C
   Q: 633  AVCLVCGEAGKEDtveeeEgkfnlMLMECSICNEIIHPGCLKVSgpvgtGNKQTPTSQ--DSPLC 695
           79*********9977765156789*******************988887777777765..34444 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MAGPQMGGSA EDHPSRKRHA AEKQKKETII YTKCYEFESA TQRPIDRQRY DENEDLSDVE 60
EIVSVRGFSL EEKLRSQLYQ GDFVHAMEGK DFNYEYVQRE ALRVPLIFRE KDGLGIKMPD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGGTC CGCAAATGGG GGGATCTGCA GAGGATCACC CCTCACGAAA AAGACATGCA 60
GCAGAAAAGC AAAAAAAGGA AACAATTATA TATACAAAAT GCTATGAATT TGAGTCGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC

Pfam

PF00646--F-box
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC

Gene Ontology

GO:0031519--C:PcG protein complex
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0048596--P:embryonic camera-type eye morphogenesis
GO:0021592--P:fourth ventricle development
GO:0035518--P:histone H2A monoubiquitination
GO:0070544--P:histone H3-K36 demethylation
GO:0021993--P:initiation of neural tube closure
GO:0021670--P:lateral ventricle development
GO:0030901--P:midbrain development
GO:0021555--P:midbrain-hindbrain boundary morphogenesis
GO:2000178--P:negative regulation of neural precursor cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030307--P:positive regulation of cell growth
GO:1902459--P:positive regulation of stem cell population maintenance
GO:0007283--P:spermatogenesis
GO:0021678--P:third ventricle development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	93.78	0.00e+00	2248.00
IUUC-Apl-003787	Anas platyrhynchos	82.25	0.00e+00	1885.00
IUUC-Aca-004247	Anolis carolinensis	77.35	0.00e+00	1757.00
IUUC-Bta-013531	Bos taurus	93.62	0.00e+00	2261.00
IUUC-Cel-018303	Caenorhabditis elegans	44.55	3.00e-82	300.00
IUUC-Cja-018876	Callithrix jacchus	91.62	0.00e+00	2189.00
IUUC-Cfa-020857	Canis familiaris	93.78	0.00e+00	2263.00
IUUC-Cpo-021967	Cavia porcellus	89.68	0.00e+00	2069.00
IUUC-Csa-023210	Chlorocebus sabaeus	96.10	0.00e+00	2224.00
IUUC-Dre-028272	Danio rerio	63.82	0.00e+00	1485.00
IUUC-Dno-030034	Dasypus novemcinctus	92.06	0.00e+00	2174.00
IUUC-Dor-030736	Dipodomys ordii	83.74	0.00e+00	953.00
IUUC-Eca-034255	Equus caballus	94.24	0.00e+00	2180.00
IUUC-Eeu-035038	Erinaceus europaeus	94.75	0.00e+00	1143.00
IUUC-Fca-035786	Felis catus	93.32	0.00e+00	2230.00
IUUC-Fal-037589	Ficedula albicollis	81.80	0.00e+00	1969.00
IUUC-Gga-041103	Gallus gallus	86.15	0.00e+00	1123.00
IUUC-Gac-041304	Gasterosteus aculeatus	61.64	0.00e+00	1469.00
IUUC-Ggo-044522	Gorilla gorilla	84.63	0.00e+00	1930.00
IUUC-Hsa-045877	Homo sapiens	95.44	0.00e+00	2318.00
IUUC-Itr-049003	Ictidomys tridecemlineatus	94.21	0.00e+00	1278.00
IUUC-Lch-049950	Latimeria chalumnae	76.49	0.00e+00	1853.00
IUUC-Loc-051972	Lepisosteus oculatus	71.19	0.00e+00	1050.00
IUUC-Laf-053623	Loxodonta africana	93.83	0.00e+00	2145.00
IUUC-Mcc-054943	Macaca mulatta	96.34	0.00e+00	2332.00
IUUC-Meu-056259	Macropus eugenii	83.50	0.00e+00	2006.00
IUUC-Mga-059671	Meleagris gallopavo	83.12	0.00e+00	1937.00
IUUC-Mmr-061003	Microcebus murinus	93.76	0.00e+00	2245.00
IUUC-Mmu-063584	Mus musculus	91.08	0.00e+00	2182.00
IUUC-Mpu-066056	Mustela putorius furo	93.70	0.00e+00	2234.00
IUUC-Mlu-067850	Myotis lucifugus	93.45	0.00e+00	2239.00
IUUC-Nle-069837	Nomascus leucogenys	92.17	0.00e+00	1992.00
IUUC-Opr-070943	Ochotona princeps	88.72	0.00e+00	2112.00
IUUC-Ont-071663	Oreochromis niloticus	64.93	0.00e+00	1543.00
IUUC-Oan-072934	Ornithorhynchus anatinus	73.66	0.00e+00	1226.00
IUUC-Ocu-074706	Oryctolagus cuniculus	93.39	0.00e+00	2254.00
IUUC-Ola-086543	Oryzias latipes	63.02	0.00e+00	1512.00
IUUC-Oga-088671	Otolemur garnettii	79.66	0.00e+00	958.00
IUUC-Oar-089560	Ovis aries	88.70	0.00e+00	2163.00
IUUC-Ptr-090875	Pan troglodytes	95.44	0.00e+00	2347.00
IUUC-Psi-093382	Pelodiscus sinensis	82.16	0.00e+00	1989.00
IUUC-Pma-094687	Petromyzon marinus	56.77	5.00e-92	332.00
IUUC-Pfo-096272	Poecilia formosa	63.77	0.00e+00	1472.00
IUUC-Pab-097907	Pongo abelii	90.96	0.00e+00	2164.00
IUUC-Pca-100628	Procavia capensis	81.92	0.00e+00	1820.00
IUUC-Pva-102956	Pteropus vampyrus	89.01	0.00e+00	1127.00
IUUC-Rno-105722	Rattus norvegicus	91.21	0.00e+00	1766.00
IUUC-Sha-106626	Sarcophilus harrisii	78.94	0.00e+00	1790.00
IUUC-Ssc-115918	Sus scrofa	92.80	0.00e+00	1718.00
IUUC-Tru-118638	Takifugu rubripes	68.82	0.00e+00	948.00
IUUC-Tbe-127654	Tupaia belangeri	81.00	0.00e+00	1666.00
IUUC-Ttr-128821	Tursiops truncatus	85.47	0.00e+00	2045.00
IUUC-Xtr-131823	Xenopus tropicalis	72.90	0.00e+00	1701.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence