iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Post-translational Modifications (PTMs)
CPLM	dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.50e-08	35.1	267	317

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClkls...veeelpnsekwiCpkCr 52
           +C +C++++++ + +++C++C+ewfH +C+++s        +n e++iCp+C+
   Q: 267  YC-ICRQPHNN-RFMICCDRCEEWFHGDCVGISearGRLLERNGEDYICPNCT 317
           89.*******5.58999999*************7654444567777******6 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDDKGDLSNE EAPKAIKPTS KEFRKTWGFR RTTIAKREGA GDTEVDPSEQ QPQQHNLSLR 60
RSGRQPKRTE RVEEFLTTVR RRGRKNVPVS LEDSSEPTSS TVTDVETASE GSVESSSEIR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTGGTCAA GAGGCAGTCC CCACTGTCCC TTTGGTTGTT TGAAGCTCCG GAATCTTCTC 60
ATTGATGAAC TGTGACTGAC AACAGTGTGG TGAGGCTTGT CCATCTGCTG GACTTGGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR033082--DIDO1
IPR012921--SPOC_C
IPR003618--TFIIS_cen_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51321--TFIIS_CENTRAL
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD
PF07744--SPOC
PF07500--TFIIS_M

SMART

SM00249--PHD
SM00510--TFS2M

Gene Ontology

GO:0005634--C:nucleus
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding
GO:0097190--P:apoptotic signaling pathway
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001202	Ailuropoda melanoleuca	70.08	0.00e+00	1683.00
IUUC-Apl-003835	Anas platyrhynchos	63.18	2.00e-162	566.00
IUUC-Aca-004562	Anolis carolinensis	51.93	0.00e+00	1654.00
IUUC-Ani-009326	Aspergillus nidulans	53.57	5.00e-14	73.20
IUUC-Bta-013233	Bos taurus	65.78	0.00e+00	2078.00
IUUC-Cja-019811	Callithrix jacchus	73.37	0.00e+00	639.00
IUUC-Cfa-021034	Canis familiaris	73.77	0.00e+00	1529.00
IUUC-Cpo-021803	Cavia porcellus	72.65	0.00e+00	2541.00
IUUC-Csa-023686	Chlorocebus sabaeus	71.44	0.00e+00	2320.00
IUUC-Csv-026099	Ciona savignyi	65.45	2.00e-23	102.00
IUUC-Cgl-026411	Colletotrichum gloeosporioides	55.56	5.00e-15	75.50
IUUC-Dre-028475	Danio rerio	59.14	6.00e-61	228.00
IUUC-Dno-029513	Dasypus novemcinctus	72.60	0.00e+00	1424.00
IUUC-Dor-030833	Dipodomys ordii	68.91	0.00e+00	2026.00
IUUC-Dse-031262	Dothistroma septosporum	55.77	9.00e-15	75.90
IUUC-Ete-032750	Echinops telfairi	58.90	0.00e+00	767.00
IUUC-Fal-036812	Ficedula albicollis	54.68	0.00e+00	1745.00
IUUC-Fox-037812	Fusarium oxysporum	47.06	1.00e-12	67.80
IUUC-Fso-038446	Fusarium solani	50.00	1.00e-13	70.90
IUUC-Ggr-039960	Gaeumannomyces graminis	50.00	2.00e-13	70.90
IUUC-Gga-040620	Gallus gallus	62.68	4.00e-159	555.00
IUUC-Gac-041527	Gasterosteus aculeatus	41.27	0.00e+00	727.00
IUUC-Ggo-044747	Gorilla gorilla	71.43	0.00e+00	2411.00
IUUC-Hsa-046225	Homo sapiens	71.34	0.00e+00	2390.00
IUUC-Hvu-047160	Hordeum vulgare	55.56	2.00e-10	62.40
IUUC-Itr-048422	Ictidomys tridecemlineatus	77.41	0.00e+00	1520.00
IUUC-Kpa-049206	Komagataella pastoris	27.97	2.00e-08	54.70
IUUC-Lch-050039	Latimeria chalumnae	52.32	0.00e+00	769.00
IUUC-Laf-053940	Loxodonta africana	67.24	0.00e+00	2194.00
IUUC-Mcc-055809	Macaca mulatta	71.48	0.00e+00	2344.00
IUUC-Mor-057044	Magnaporthe oryzae	50.00	6.00e-13	68.90
IUUC-Mpo-057588	Magnaporthe poae	50.00	2.00e-13	70.50
IUUC-Mga-060017	Meleagris gallopavo	57.21	0.00e+00	1778.00
IUUC-Mmr-061055	Microcebus murinus	71.61	0.00e+00	2297.00
IUUC-Mdo-062683	Monodelphis domestica	67.73	0.00e+00	1469.00
IUUC-Mmu-064010	Mus musculus	91.64	0.00e+00	3290.00
IUUC-Mac-064704	Musa acuminata	57.58	6.00e-10	58.50
IUUC-Mpu-066844	Mustela putorius furo	66.77	0.00e+00	2095.00
IUUC-Mlu-067160	Myotis lucifugus	67.37	0.00e+00	2277.00
IUUC-Nle-070068	Nomascus leucogenys	70.79	0.00e+00	2407.00
IUUC-Ont-072366	Oreochromis niloticus	42.59	6.00e-149	523.00
IUUC-Oan-072746	Ornithorhynchus anatinus	66.45	0.00e+00	1225.00
IUUC-Ocu-074336	Oryctolagus cuniculus	67.14	0.00e+00	1503.00
IUUC-Ogl-076925	Oryza glaberrima	32.67	8.00e-12	64.30
IUUC-Ola-086406	Oryzias latipes	39.30	4.00e-136	480.00
IUUC-Olu-087633	Ostreococcus lucimarinus	40.35	5.00e-09	56.20
IUUC-Oga-088506	Otolemur garnettii	69.72	0.00e+00	2487.00
IUUC-Ptr-091448	Pan troglodytes	70.61	0.00e+00	2329.00
IUUC-Pan-092481	Papio anubis	70.49	0.00e+00	2326.00
IUUC-Psi-092995	Pelodiscus sinensis	56.23	0.00e+00	1524.00
IUUC-Pab-098673	Pongo abelii	71.29	0.00e+00	2381.00
IUUC-Sha-107260	Sarcophilus harrisii	68.82	0.00e+00	1525.00
IUUC-Sja-107904	Schizosaccharomyces japonicus	32.52	5.00e-15	76.60
IUUC-Stu-112199	Solanum tuberosum	40.28	2.00e-12	67.40
IUUC-Tgu-117059	Taeniopygia guttata	55.65	0.00e+00	1764.00
IUUC-Tru-117650	Takifugu rubripes	47.92	8.00e-128	452.00
IUUC-Tre-122185	Trichoderma reesei	49.25	1.00e-15	77.40
IUUC-Tvi-122269	Trichoderma virens	58.82	6.00e-15	75.10
IUUC-Ttr-129315	Tursiops truncatus	66.79	0.00e+00	1479.00
IUUC-Vpa-130265	Vicugna pacos	74.90	2.00e-100	360.00
IUUC-Xma-133754	Xiphophorus maculatus	43.09	6.00e-139	489.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence