iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035635

Ensembl Protein ID

ENSFCAP00000017702.1

UniProt Accession

M3WTL6; M3WTL6_FELCA

Genbank Protein ID

ENSFCAP00000017702

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AANG02181833

Gene Name

ING5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000028740.1	ENSFCAT00000021901.1	ENSFCAP00000017702.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.30e-09	36.8	217	264

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C +
   Q: 217  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCVQ 264
           69*.*******99..*********99***********...999997.******87 PP

Organism

Felis catus

Protein Sequence
(Fasta)

VSGIENLPCE LQRNFQLMRE LDQRTEDKKA EIDILAAEYI STVKTLSPDQ RVEHLQKIQS 60
AYSKCKEYSD DKVQLAMQTY EMVDKHIRRL DADLARFEAD LKDKMEGSDF ESSGGRGLKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTCAGGTA TCGAGAACCT TCCTTGTGAG CTGCAGAGGA ACTTCCAGCT CATGAGAGAG 60
CTGGACCAGA GGACGGAAGG TGGGTCCAGG CCTTACAGTA CAGCCGGCGG TGTGCTCTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	83.21	7.00e-103	366.00
IUUC-Apl-003516	Anas platyrhynchos	75.00	3.00e-87	313.00
IUUC-Bta-012590	Bos taurus	82.40	5.00e-106	376.00
IUUC-Cja-019518	Callithrix jacchus	81.11	2.00e-105	374.00
IUUC-Cfa-020620	Canis familiaris	82.96	5.00e-111	393.00
IUUC-Cpo-022085	Cavia porcellus	81.85	1.00e-103	368.00
IUUC-Csa-023421	Chlorocebus sabaeus	82.22	8.00e-103	365.00
IUUC-Dor-030910	Dipodomys ordii	94.94	3.00e-46	178.00
IUUC-Eca-033493	Equus caballus	81.65	1.00e-106	378.00
IUUC-Fal-036998	Ficedula albicollis	76.30	3.00e-102	364.00
IUUC-Gmo-039035	Gadus morhua	63.47	4.00e-83	300.00
IUUC-Gga-040578	Gallus gallus	75.56	2.00e-102	364.00
IUUC-Hsa-045965	Homo sapiens	82.22	8.00e-103	365.00
IUUC-Mcc-055455	Macaca mulatta	83.21	5.00e-103	366.00
IUUC-Mga-059312	Meleagris gallopavo	74.38	6.00e-87	312.00
IUUC-Mmr-061351	Microcebus murinus	82.77	7.00e-102	363.00
IUUC-Mdo-062282	Monodelphis domestica	80.00	2.00e-100	358.00
IUUC-Mmu-063201	Mus musculus	78.89	2.00e-102	364.00
IUUC-Mpu-066302	Mustela putorius furo	82.96	2.00e-104	371.00
IUUC-Mlu-068192	Myotis lucifugus	81.85	4.00e-104	370.00
IUUC-Nle-069708	Nomascus leucogenys	77.13	8.00e-56	208.00
IUUC-Oan-073652	Ornithorhynchus anatinus	80.74	1.00e-105	375.00
IUUC-Ocu-073871	Oryctolagus cuniculus	80.44	2.00e-104	371.00
IUUC-Oga-088066	Otolemur garnettii	76.05	2.00e-87	314.00
IUUC-Ptr-091665	Pan troglodytes	82.22	8.00e-103	365.00
IUUC-Pan-091875	Papio anubis	82.22	8.00e-103	365.00
IUUC-Psi-093904	Pelodiscus sinensis	77.87	1.00e-92	332.00
IUUC-Pca-100600	Procavia capensis	92.41	8.00e-46	176.00
IUUC-Pva-102282	Pteropus vampyrus	77.78	3.00e-105	374.00
IUUC-Rno-105646	Rattus norvegicus	78.52	6.00e-102	362.00
IUUC-Sha-107031	Sarcophilus harrisii	81.11	5.00e-102	363.00
IUUC-Tgu-116837	Taeniopygia guttata	75.93	1.00e-101	362.00
IUUC-Tca-121597	Theobroma cacao	73.44	3.00e-28	118.00
IUUC-Vvi-131487	Vitis vinifera	67.19	1.00e-26	113.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence