iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/ZnF/NZF	NZF	23596533

Classification

Family	E-value	Score	Start	End
UBD/ZnF/NZF	4.70e-14	51.6	19	48

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 1    aeaqWaCsaCTflNePeavkCemCsrpRgc 30
           +e++W+Cs+CT++N++ea+kC+mC+ ++g+
   Q: 19   EENFWDCSVCTYRNSAEAFKCRMCDVRKGT 48
           589*************************95 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MDKKSSPVRR QKRQAKVIEE NFWDCSVCTY RNSAEAFKCR MCDVRKGTST RKPRLNSALV 60
AQQAATLPGA SVNMPNGKSA SGSRHGSGHD RQRHKRYPAR LKNVDRSTAQ TREVTVNSVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCGTAAGC TTCACAATAA AATGCAAACA CAAAACAATG ACAAGCCACA TTTCAAAATA 60
AACGTAGTTT GGCGCCCAAT CGAAAAGTGA GTTGCCAGAT CAGCACCATA CGCTAGCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR033774--YAF2_RYBP
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF17219--YAF2_RYBP
PF00641--zf-RanBP

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0016604--C:nuclear body
GO:0003677--F:DNA binding
GO:0008270--F:zinc ion binding
GO:0043066--P:negative regulation of apoptotic process
GO:0050777--P:negative regulation of immune response
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

dme:Dmel_CG12190

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001905	Ailuropoda melanoleuca	52.17	9.00e-23	98.60
IUUC-Atr-002761	Amborella trichopoda	50.00	4.00e-03	34.70
IUUC-Apl-003475	Anas platyrhynchos	76.79	7.00e-21	93.20
IUUC-Aca-004478	Anolis carolinensis	48.12	1.00e-26	111.00
IUUC-Afl-008541	Aspergillus flavus	45.16	1.40e-01	28.10
IUUC-Ame-011908	Astyanax mexicanus	50.75	1.00e-28	118.00
IUUC-Bta-012681	Bos taurus	42.86	9.00e-16	75.50
IUUC-Cja-018878	Callithrix jacchus	41.40	2.00e-20	90.90
IUUC-Cfa-020696	Canis familiaris	43.62	4.00e-19	86.70
IUUC-Cpo-022486	Cavia porcellus	52.00	5.00e-23	99.80
IUUC-Csa-023628	Chlorocebus sabaeus	73.77	1.00e-20	92.40
IUUC-Cho-024392	Choloepus hoffmanni	52.63	2.00e-22	97.80
IUUC-Cin-025723	Ciona intestinalis	53.72	5.00e-24	102.00
IUUC-Dre-028175	Danio rerio	52.00	2.00e-24	104.00
IUUC-Dno-030093	Dasypus novemcinctus	66.67	4.00e-06	42.70
IUUC-Dor-030691	Dipodomys ordii	63.89	4.00e-06	43.50
IUUC-Ete-032320	Echinops telfairi	75.00	6.00e-19	86.30
IUUC-Eca-034330	Equus caballus	79.25	1.00e-20	92.00
IUUC-Eeu-034971	Erinaceus europaeus	52.68	6.00e-22	95.50
IUUC-Fca-036586	Felis catus	66.67	4.00e-06	42.70
IUUC-Fal-036647	Ficedula albicollis	83.33	2.00e-18	84.70
IUUC-Gmo-038950	Gadus morhua	49.59	1.00e-24	104.00
IUUC-Gga-040428	Gallus gallus	48.87	3.00e-22	97.40
IUUC-Gac-042503	Gasterosteus aculeatus	52.14	4.00e-27	113.00
IUUC-Ggo-044644	Gorilla gorilla	52.00	4.00e-23	99.80
IUUC-Hsa-046310	Homo sapiens	41.40	2.00e-20	90.90
IUUC-Itr-048494	Ictidomys tridecemlineatus	64.71	8.00e-16	73.60
IUUC-Lch-050130	Latimeria chalumnae	49.62	2.00e-28	117.00
IUUC-Loc-052825	Lepisosteus oculatus	40.48	3.00e-24	103.00
IUUC-Laf-054318	Loxodonta africana	48.12	2.00e-22	97.40
IUUC-Mcc-055623	Macaca mulatta	79.25	2.00e-20	91.70
IUUC-Meu-056465	Macropus eugenii	47.29	3.00e-26	110.00
IUUC-Mor-057038	Magnaporthe oryzae	44.44	1.30e+00	27.30
IUUC-Mga-059338	Meleagris gallopavo	66.67	4.00e-06	42.70
IUUC-Mmr-060766	Microcebus murinus	55.22	5.00e-18	82.00
IUUC-Mdo-062390	Monodelphis domestica	48.87	4.00e-23	100.00
IUUC-Mmu-063437	Mus musculus	49.23	2.00e-25	107.00
IUUC-Mpu-065711	Mustela putorius furo	78.85	5.00e-20	90.10
IUUC-Mlu-067600	Myotis lucifugus	44.44	7.00e-06	42.00
IUUC-Nle-070014	Nomascus leucogenys	41.40	2.00e-20	90.90
IUUC-Opr-070623	Ochotona princeps	70.00	4.00e-06	43.50
IUUC-Ont-071471	Oreochromis niloticus	50.74	9.00e-29	118.00
IUUC-Oan-072949	Ornithorhynchus anatinus	73.77	1.00e-20	92.40
IUUC-Ocu-073946	Oryctolagus cuniculus	51.22	4.00e-25	106.00
IUUC-Ola-086923	Oryzias latipes	47.37	5.00e-27	112.00
IUUC-Oga-089162	Otolemur garnettii	66.67	4.00e-06	43.50
IUUC-Oar-090289	Ovis aries	62.71	1.00e-16	77.40
IUUC-Ptr-091285	Pan troglodytes	41.40	2.00e-20	90.90
IUUC-Pan-091877	Papio anubis	73.77	1.00e-20	92.40
IUUC-Psi-093195	Pelodiscus sinensis	80.00	1.00e-19	89.00
IUUC-Pma-094646	Petromyzon marinus	51.82	4.00e-29	120.00
IUUC-Pfo-097428	Poecilia formosa	47.76	1.00e-25	108.00
IUUC-Pab-098578	Pongo abelii	80.00	2.00e-19	88.20
IUUC-Pca-100706	Procavia capensis	61.11	6.00e-06	43.10
IUUC-Pva-102993	Pteropus vampyrus	48.87	2.00e-24	103.00
IUUC-Rno-105835	Rattus norvegicus	51.88	8.00e-26	108.00
IUUC-Sha-107285	Sarcophilus harrisii	48.87	2.00e-23	100.00
IUUC-Sar-113234	Sorex araneus	79.17	6.00e-20	89.70
IUUC-Ssc-116262	Sus scrofa	63.89	4.00e-06	43.10
IUUC-Tgu-116993	Taeniopygia guttata	48.87	3.00e-22	97.10
IUUC-Tru-118599	Takifugu rubripes	50.38	7.00e-27	112.00
IUUC-Tsy-119409	Tarsius syrichta	66.67	4.00e-06	42.70
IUUC-Tni-119964	Tetraodon nigroviridis	53.38	8.00e-31	125.00
IUUC-Tre-121881	Trichoderma reesei	38.71	2.00e-02	32.70
IUUC-Tvi-122470	Trichoderma virens	44.83	4.00e-03	35.00
IUUC-Tbe-127332	Tupaia belangeri	78.85	5.00e-20	90.10
IUUC-Ttr-128187	Tursiops truncatus	50.40	8.00e-24	102.00
IUUC-Vpa-130247	Vicugna pacos	52.03	5.00e-23	99.40
IUUC-Xtr-132148	Xenopus tropicalis	48.12	1.00e-27	114.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence