iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052774

Ensembl Protein ID

ENSLOCP00000004301.1

UniProt Accession

W5M7E3; W5M7E3_LEPOC

Genbank Protein ID

ENSLOCP00000004301

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01029690

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000003624.1	ENSLOCT00000004309.1	ENSLOCP00000004301.1
ENSLOCG00000003624.1	ENSLOCT00000004328.1	ENSLOCP00000004320.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-06	27.9	398	426
E3 activity/RING/RING	4.30e-06	27.3	10	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H  ++t++a+ +d  l+++Gs  +t++++D
   Q: 398  HDYPITSVAWaPDgELFAVGSF-NTLRLCD 426
           8899*******99888888886.6****99 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw......pglknssskefrCPlCr 46
           C++C++ f+d p+vlpC H+f++ Cl+++      +   +  ++  +CP Cr
   Q: 10   CSVCYSLFSD-PRVLPCSHTFCKGCLENVlqvsvnFSIWRPLRTPLKCPHCR 60
           **********.**************9888665665333355777778**998 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MESLEEDLTC SVCYSLFSDP RVLPCSHTFC KGCLENVLQV SVNFSIWRPL RTPLKCPHCR 60
NMVELPPTGV EALPTNVSLR AIIEKFQRDD QSKPPSCQEH PKQPLNVYCL QDRQLICGVC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAAGTC TGGAGGAGGA TCTCACGTGT TCAGTGTGCT ACTCGTTGTT CAGTGACCCT 60
CGTGTTCTGC CGTGCTCCCA TACCTTTTGT AAAGGCTGTT TGGAAAATGT TCTCCAGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0060271--P:cilium assembly
GO:0060026--P:convergent extension
GO:0008104--P:protein localization
GO:0060042--P:retina morphogenesis in camera-type eye

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001564	Ailuropoda melanoleuca	86.05	8.00e-158	550.00
IUUC-Apl-003721	Anas platyrhynchos	80.23	0.00e+00	1048.00
IUUC-Aca-004488	Anolis carolinensis	79.83	0.00e+00	1048.00
IUUC-Ame-011402	Astyanax mexicanus	81.37	3.00e-166	578.00
IUUC-Bta-013037	Bos taurus	70.08	0.00e+00	904.00
IUUC-Cel-018360	Caenorhabditis elegans	40.78	1.00e-152	533.00
IUUC-Cja-019076	Callithrix jacchus	68.92	0.00e+00	1393.00
IUUC-Cfa-020999	Canis familiaris	78.90	0.00e+00	1045.00
IUUC-Cpo-021333	Cavia porcellus	71.04	0.00e+00	876.00
IUUC-Cre-022899	Chlamydomonas reinhardtii	46.92	2.00e-153	536.00
IUUC-Csa-023699	Chlorocebus sabaeus	78.37	0.00e+00	1056.00
IUUC-Cho-024904	Choloepus hoffmanni	73.80	6.00e-141	494.00
IUUC-Cin-025399	Ciona intestinalis	59.80	0.00e+00	794.00
IUUC-Csv-026186	Ciona savignyi	57.35	0.00e+00	770.00
IUUC-Dre-028276	Danio rerio	78.50	0.00e+00	1050.00
IUUC-Dno-029824	Dasypus novemcinctus	78.41	0.00e+00	1063.00
IUUC-Dor-031141	Dipodomys ordii	74.92	0.00e+00	981.00
IUUC-Dme-031620	Drosophila melanogaster	35.08	3.00e-110	392.00
IUUC-Ete-033028	Echinops telfairi	55.24	0.00e+00	1072.00
IUUC-Eca-033339	Equus caballus	78.59	0.00e+00	1030.00
IUUC-Eeu-034909	Erinaceus europaeus	76.19	0.00e+00	836.00
IUUC-Fca-035780	Felis catus	78.37	0.00e+00	1034.00
IUUC-Fal-037447	Ficedula albicollis	74.51	0.00e+00	945.00
IUUC-Gmo-038657	Gadus morhua	62.35	0.00e+00	1145.00
IUUC-Gga-040689	Gallus gallus	80.07	0.00e+00	1047.00
IUUC-Gac-041586	Gasterosteus aculeatus	72.35	0.00e+00	1481.00
IUUC-Ggo-045307	Gorilla gorilla	51.66	2.00e-98	352.00
IUUC-Hsa-046264	Homo sapiens	69.59	0.00e+00	1401.00
IUUC-Itr-048757	Ictidomys tridecemlineatus	78.99	0.00e+00	933.00
IUUC-Lch-050459	Latimeria chalumnae	80.23	0.00e+00	1073.00
IUUC-Laf-053765	Loxodonta africana	78.07	0.00e+00	1021.00
IUUC-Mcc-055052	Macaca mulatta	78.37	0.00e+00	1056.00
IUUC-Meu-056368	Macropus eugenii	72.97	0.00e+00	701.00
IUUC-Mga-059488	Meleagris gallopavo	80.23	0.00e+00	1050.00
IUUC-Mmr-061527	Microcebus murinus	78.49	0.00e+00	1053.00
IUUC-Mdo-062850	Monodelphis domestica	68.84	0.00e+00	1377.00
IUUC-Mmu-063117	Mus musculus	77.44	0.00e+00	1029.00
IUUC-Mpu-066550	Mustela putorius furo	79.06	0.00e+00	1070.00
IUUC-Mlu-067772	Myotis lucifugus	75.21	0.00e+00	961.00
IUUC-Nle-069215	Nomascus leucogenys	77.40	0.00e+00	1043.00
IUUC-Opr-070725	Ochotona princeps	58.77	0.00e+00	754.00
IUUC-Ont-072147	Oreochromis niloticus	79.58	0.00e+00	1062.00
IUUC-Oan-073382	Ornithorhynchus anatinus	55.48	1.00e-102	366.00
IUUC-Ocu-073896	Oryctolagus cuniculus	69.30	0.00e+00	1372.00
IUUC-Ola-086767	Oryzias latipes	68.70	0.00e+00	1348.00
IUUC-Oga-088113	Otolemur garnettii	78.18	0.00e+00	1060.00
IUUC-Oar-089683	Ovis aries	75.36	0.00e+00	996.00
IUUC-Ptr-091563	Pan troglodytes	78.37	0.00e+00	1056.00
IUUC-Pan-092042	Papio anubis	78.37	0.00e+00	1056.00
IUUC-Psi-093306	Pelodiscus sinensis	80.68	0.00e+00	1087.00
IUUC-Pma-094162	Petromyzon marinus	39.21	4.00e-58	218.00
IUUC-Ppa-095694	Physcomitrella patens	45.31	2.00e-168	586.00
IUUC-Pfo-096800	Poecilia formosa	77.36	0.00e+00	1024.00
IUUC-Pab-098356	Pongo abelii	78.37	0.00e+00	1056.00
IUUC-Pva-102246	Pteropus vampyrus	73.29	0.00e+00	953.00
IUUC-Rno-105195	Rattus norvegicus	77.85	0.00e+00	1029.00
IUUC-Sha-107056	Sarcophilus harrisii	79.02	0.00e+00	1043.00
IUUC-Smo-109240	Selaginella moellendorffii	43.34	4.00e-142	498.00
IUUC-Sly-111770	Solanum lycopersicum	31.52	2.00e-07	49.70
IUUC-Sar-113301	Sorex araneus	69.05	2.00e-122	433.00
IUUC-Ssc-115809	Sus scrofa	51.42	3.00e-94	338.00
IUUC-Tgu-117127	Taeniopygia guttata	77.80	0.00e+00	1009.00
IUUC-Tru-118663	Takifugu rubripes	73.21	0.00e+00	981.00
IUUC-Tsy-119207	Tarsius syrichta	76.94	0.00e+00	734.00
IUUC-Tni-120705	Tetraodon nigroviridis	72.73	0.00e+00	980.00
IUUC-Tbe-127434	Tupaia belangeri	65.68	0.00e+00	1127.00
IUUC-Ttr-128937	Tursiops truncatus	78.08	0.00e+00	1036.00
IUUC-Vpa-130518	Vicugna pacos	73.38	0.00e+00	932.00
IUUC-Xtr-131879	Xenopus tropicalis	65.50	0.00e+00	995.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence