iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003484

Ensembl Protein ID

ENSAPLP00000000986.1

UniProt Accession

U3I166; U3I166_ANAPL

Genbank Protein ID

ENSAPLP00000000986

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01024161

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000001565.1	ENSAPLT00000001557.1	ENSAPLP00000000986.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	6.30e-13	48.1	110	153

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 5    wllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           ++l ++ +SLqh CR++I++c+ +     i++LPLP +Lk+YL+++ yq
   Q: 110  KPLYTSAPSLQHRCRITINKCTNQ-----IWELPLPTRLKEYLKEYRYQ 153
           5688999***************99.....8***************9886 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

SALVTGWYWG SMSVAEAKER LQDAPEGTFL VRDSSHSEYL LTISVKTSAG PTNLRIEYQD 60
GKFRLDSITC VRSRLKQFNS VVHLIEYYVL MCKDRTETPS NGTVHLYLNK PLYTSAPSLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTGCTCTCG TGACAGGATG GTACTGGGGC AGCATGAGCG TTGCTGAAGC CAAGGAGAGG 60
TTACAGGATG CCCCCGAAGG GACTTTTTTG GTTCGGGACA GCTCGCATTC AGAGTACCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	79.08	3.00e-71	260.00
IUUC-Aca-004253	Anolis carolinensis	84.31	6.00e-76	276.00
IUUC-Ame-011267	Astyanax mexicanus	61.54	2.00e-53	201.00
IUUC-Bta-013183	Bos taurus	79.08	7.00e-72	262.00
IUUC-Cja-018862	Callithrix jacchus	80.39	1.00e-72	265.00
IUUC-Cfa-020226	Canis familiaris	78.95	8.00e-71	259.00
IUUC-Cpo-022414	Cavia porcellus	80.39	2.00e-72	264.00
IUUC-Csa-023758	Chlorocebus sabaeus	79.74	5.00e-72	263.00
IUUC-Cho-024471	Choloepus hoffmanni	73.03	4.00e-59	220.00
IUUC-Dre-028288	Danio rerio	64.74	1.00e-56	211.00
IUUC-Dno-029036	Dasypus novemcinctus	79.74	2.00e-72	264.00
IUUC-Dor-030447	Dipodomys ordii	79.47	8.00e-71	258.00
IUUC-Ete-033023	Echinops telfairi	80.39	1.00e-72	265.00
IUUC-Eca-033422	Equus caballus	44.38	4.00e-38	150.00
IUUC-Eeu-034806	Erinaceus europaeus	42.70	2.00e-35	142.00
IUUC-Fca-036469	Felis catus	79.74	4.00e-72	263.00
IUUC-Fal-036642	Ficedula albicollis	96.64	9.00e-85	305.00
IUUC-Gmo-039331	Gadus morhua	66.67	1.00e-30	124.00
IUUC-Gga-040809	Gallus gallus	99.33	4.00e-87	312.00
IUUC-Gac-041398	Gasterosteus aculeatus	60.39	4.00e-53	200.00
IUUC-Ggo-045341	Gorilla gorilla	80.39	1.00e-72	265.00
IUUC-Hsa-046557	Homo sapiens	80.39	6.00e-73	266.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	79.61	1.00e-71	261.00
IUUC-Lch-050160	Latimeria chalumnae	62.50	2.00e-46	177.00
IUUC-Loc-051825	Lepisosteus oculatus	63.64	4.00e-57	213.00
IUUC-Laf-053560	Loxodonta africana	79.74	6.00e-72	262.00
IUUC-Mcc-055890	Macaca mulatta	79.08	2.00e-71	261.00
IUUC-Meu-056218	Macropus eugenii	80.92	2.00e-73	267.00
IUUC-Mla-059173	Melampsora laricipopulina	23.97	2.70e+00	25.40
IUUC-Mga-059755	Meleagris gallopavo	96.75	7.00e-87	312.00
IUUC-Mmr-061387	Microcebus murinus	79.74	4.00e-72	263.00
IUUC-Mdo-062383	Monodelphis domestica	82.24	5.00e-74	269.00
IUUC-Mmu-063443	Mus musculus	78.43	6.00e-71	259.00
IUUC-Mpu-066459	Mustela putorius furo	77.78	6.00e-70	256.00
IUUC-Mlu-068040	Myotis lucifugus	79.74	4.00e-72	263.00
IUUC-Nle-069016	Nomascus leucogenys	80.26	5.00e-72	263.00
IUUC-Opr-071087	Ochotona princeps	75.48	2.00e-70	257.00
IUUC-Ont-072340	Oreochromis niloticus	59.38	2.00e-53	201.00
IUUC-Oan-073443	Ornithorhynchus anatinus	82.35	8.00e-75	272.00
IUUC-Ocu-074539	Oryctolagus cuniculus	78.29	6.00e-70	256.00
IUUC-Ola-087004	Oryzias latipes	56.33	1.00e-50	191.00
IUUC-Oga-088438	Otolemur garnettii	79.08	1.00e-71	261.00
IUUC-Oar-089932	Ovis aries	79.08	1.00e-71	261.00
IUUC-Ptr-091037	Pan troglodytes	80.39	1.00e-72	265.00
IUUC-Pan-092767	Papio anubis	79.74	5.00e-72	263.00
IUUC-Psi-093099	Pelodiscus sinensis	88.82	1.00e-77	281.00
IUUC-Pma-094671	Petromyzon marinus	44.00	7.00e-35	139.00
IUUC-Pfo-097073	Poecilia formosa	53.55	3.00e-48	184.00
IUUC-Pab-098319	Pongo abelii	80.39	1.00e-72	265.00
IUUC-Pca-101117	Procavia capensis	79.74	3.00e-71	260.00
IUUC-Pva-102117	Pteropus vampyrus	79.08	3.00e-71	260.00
IUUC-Rno-105913	Rattus norvegicus	77.78	5.00e-70	256.00
IUUC-Sha-106500	Sarcophilus harrisii	81.46	6.00e-73	266.00
IUUC-Sar-113001	Sorex araneus	43.26	5.00e-37	147.00
IUUC-Ssc-115252	Sus scrofa	79.74	5.00e-72	263.00
IUUC-Tgu-117524	Taeniopygia guttata	95.30	4.00e-83	299.00
IUUC-Tru-118511	Takifugu rubripes	40.69	2.00e-23	101.00
IUUC-Tsy-119335	Tarsius syrichta	78.15	1.00e-69	254.00
IUUC-Tni-120263	Tetraodon nigroviridis	57.50	2.00e-51	194.00
IUUC-Tbe-127915	Tupaia belangeri	79.08	2.00e-71	261.00
IUUC-Ttr-128372	Tursiops truncatus	79.74	7.00e-72	262.00
IUUC-Vpa-130422	Vicugna pacos	79.47	1.00e-70	258.00
IUUC-Xtr-132941	Xenopus tropicalis	77.12	4.00e-68	249.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence