iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073870

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02050853

Gene Name

SOCS6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000001076.2	ENSOCUT00000001077.2	ENSOCUP00000022707.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.50e-17	62.1	488	535

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 488  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 535
           5788999********************888...***************997 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MKKISLKTFR KSFNLNKSKE ESEFMVVQQP SLAGDFGKDD SLFGSCYGKE MASCDINSED 60
EKGGKSRSKS ESLMGTLKRR LSAKQKPKGK GSAPTGGSAD EDTFSSSSAP IVFKDVRAQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAAAA TTAGTCTCAA AACCTTTCGG AAGTCTTTCA ACTTGAATAA AAGTAAAGAA 60
GAATCTGAGT TCATGGTAGT ACAACAGCCG TCCCTAGCCG GTGACTTTGG AAAAGATGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0001772--C:immunological synapse
GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0050868--P:negative regulation of T cell activation
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

KEGG

ocu:100344911

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	94.21	0.00e+00	939.00
IUUC-Atr-002940	Amborella trichopoda	27.27	5.70e-01	28.50
IUUC-Apl-004035	Anas platyrhynchos	89.16	0.00e+00	881.00
IUUC-Aca-004782	Anolis carolinensis	86.75	0.00e+00	845.00
IUUC-Ame-011790	Astyanax mexicanus	69.05	0.00e+00	642.00
IUUC-Bta-012579	Bos taurus	95.69	2.00e-109	389.00
IUUC-Bol-015843	Brassica oleracea	28.77	2.80e-02	33.10
IUUC-Cel-018643	Caenorhabditis elegans	33.59	1.00e-11	62.80
IUUC-Cja-019528	Callithrix jacchus	94.21	0.00e+00	984.00
IUUC-Cfa-020678	Canis familiaris	93.46	0.00e+00	954.00
IUUC-Cpo-021947	Cavia porcellus	94.58	0.00e+00	996.00
IUUC-Csa-023935	Chlorocebus sabaeus	94.58	0.00e+00	967.00
IUUC-Cho-024477	Choloepus hoffmanni	91.21	0.00e+00	956.00
IUUC-Cin-025413	Ciona intestinalis	68.24	3.00e-66	245.00
IUUC-Csv-026247	Ciona savignyi	67.47	5.00e-65	241.00
IUUC-Dre-027636	Danio rerio	69.07	0.00e+00	637.00
IUUC-Dno-029048	Dasypus novemcinctus	93.27	0.00e+00	952.00
IUUC-Dor-030401	Dipodomys ordii	91.42	0.00e+00	915.00
IUUC-Ete-033116	Echinops telfairi	50.53	3.00e-60	224.00
IUUC-Eca-033825	Equus caballus	94.21	0.00e+00	915.00
IUUC-Fca-036253	Felis catus	92.71	0.00e+00	858.00
IUUC-Fal-037614	Ficedula albicollis	89.53	0.00e+00	885.00
IUUC-Fox-037898	Fusarium oxysporum	29.76	1.10e-02	33.50
IUUC-Gmo-038928	Gadus morhua	69.19	0.00e+00	667.00
IUUC-Gga-040177	Gallus gallus	88.60	0.00e+00	875.00
IUUC-Gac-042263	Gasterosteus aculeatus	71.22	0.00e+00	704.00
IUUC-Ggo-045288	Gorilla gorilla	93.83	0.00e+00	960.00
IUUC-Hsa-046409	Homo sapiens	94.21	0.00e+00	961.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	94.02	0.00e+00	924.00
IUUC-Lch-050354	Latimeria chalumnae	84.33	0.00e+00	873.00
IUUC-Loc-052319	Lepisosteus oculatus	81.34	0.00e+00	817.00
IUUC-Laf-054070	Loxodonta africana	91.96	0.00e+00	905.00
IUUC-Mcc-055045	Macaca mulatta	94.58	0.00e+00	969.00
IUUC-Meu-055917	Macropus eugenii	89.35	0.00e+00	943.00
IUUC-Mga-059273	Meleagris gallopavo	88.97	0.00e+00	876.00
IUUC-Mmr-061597	Microcebus murinus	94.58	0.00e+00	967.00
IUUC-Mdo-062492	Monodelphis domestica	63.85	1.00e-108	385.00
IUUC-Mmu-063374	Mus musculus	83.46	0.00e+00	839.00
IUUC-Mpu-065967	Mustela putorius furo	90.28	0.00e+00	899.00
IUUC-Mlu-067532	Myotis lucifugus	92.52	0.00e+00	926.00
IUUC-Nle-069373	Nomascus leucogenys	94.39	0.00e+00	962.00
IUUC-Opr-070873	Ochotona princeps	92.52	0.00e+00	969.00
IUUC-Ont-072498	Oreochromis niloticus	71.77	0.00e+00	731.00
IUUC-Oan-072943	Ornithorhynchus anatinus	73.06	4.00e-98	350.00
IUUC-Ola-086866	Oryzias latipes	90.32	2.00e-106	377.00
IUUC-Oga-089057	Otolemur garnettii	92.90	0.00e+00	931.00
IUUC-Oar-089841	Ovis aries	60.82	3.00e-165	574.00
IUUC-Ptr-091054	Pan troglodytes	94.21	0.00e+00	960.00
IUUC-Pma-094253	Petromyzon marinus	82.11	2.00e-92	332.00
IUUC-Pfo-097179	Poecilia formosa	65.06	3.00e-175	608.00
IUUC-Pab-097702	Pongo abelii	94.39	0.00e+00	962.00
IUUC-Pca-100671	Procavia capensis	87.33	1.00e-129	456.00
IUUC-Rno-106044	Rattus norvegicus	82.10	0.00e+00	830.00
IUUC-Sha-107139	Sarcophilus harrisii	88.96	0.00e+00	865.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	3.30e-02	32.00
IUUC-Ssc-115343	Sus scrofa	92.52	0.00e+00	951.00
IUUC-Tgu-117061	Taeniopygia guttata	89.16	0.00e+00	883.00
IUUC-Tni-119829	Tetraodon nigroviridis	68.21	0.00e+00	649.00
IUUC-Tae-123723	Triticum aestivum	27.50	4.20e-02	33.50
IUUC-Ttr-129148	Tursiops truncatus	91.59	0.00e+00	887.00
IUUC-Vpa-130780	Vicugna pacos	90.28	0.00e+00	863.00
IUUC-Vvi-130966	Vitis vinifera	32.69	5.80e-02	31.20
IUUC-Xtr-132513	Xenopus tropicalis	82.06	0.00e+00	846.00
IUUC-Xma-133904	Xiphophorus maculatus	68.95	0.00e+00	664.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence