iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006959

Ensembl Protein ID

AT5G17290.1

UniProt Accession

Q9FFI2; ATG5_ARATH

Genbank Protein ID

BAB10516.1; AED92409.1; BAC42232.1; AAO50633.1

Protein Name

Autophagy protein 5; Protein autophagy 5

Genbank Nucleotide ID

AB005238; CP002688; AK117572; BT005100

Gene Name

ATG5; APG5; At5g17290; MKP11_14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G17290	AT5G17290.1	AT5G17290.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/Other	23.85	4.00e-06	47.00	IUUC-Sce-106216

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Arabidopsis thaliana

Functional Description
(View)

Required for autophagy. Conjugation to ATG12 is essential for plant nutrient recycling (PubMed:16040659). Involved in a negative feedback loop that modulates NPR1-dependent salicylic acid (SA) signaling and limits senescence and immunity-related programmed cell death (PCD) in plants (PubMed:19773385). Involved in complete proteolysis of chloroplast stroma proteins in senescent leaves (PubMed:23327451). Involved in the degradation of damaged peroxisomes (PubMed:24463818).

Protein Sequence
(Fasta)

MAKEAVKYVW EGAIPLQIHL HKSDVASHPA PPPALVLAPR IGYLPLLIPL IKPYFKDSLP 60
PGEDSIWFDY KGFPLKWYIP TGVLFDLLCA EPERPWNLTI HFRGYPCNIL IPCEGEDSVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTACGCCTT ATTAATACCA CATAAAGACG CAAGAGAAGA TGACGTCATA CAGAAACAGC 60
GTCGTTTTGA AAGCTGAGTT TTTTTTGTGA AGCGAGCGAG CGTGAGAAGG TGTGACGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-0611--Plant defense
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0346--Stress response
KW-0813--Transport
KW-0832--Ubl conjugation

Interpro

IPR007239--Atg5

Pfam

PF04106--APG5

Gene Ontology

GO:0034274--C:Atg12-Atg5-Atg16 complex
GO:0034045--C:pre-autophagosomal structure membrane
GO:0000045--P:autophagosome assembly
GO:0006914--P:autophagy
GO:0006501--P:C-terminal protein lipidation
GO:0006995--P:cellular response to nitrogen starvation
GO:0050832--P:defense response to fungus
GO:0010150--P:leaf senescence
GO:0000422--P:mitophagy
GO:0044804--P:nucleophagy
GO:0015031--P:protein transport
GO:0042594--P:response to starvation

KEGG

ath:AT5G17290

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000583	Aegilops tauschii	52.09	6.00e-99	354.00
IUUC-Aml-002403	Ailuropoda melanoleuca	28.18	2.00e-31	128.00
IUUC-Atr-002645	Amborella trichopoda	53.57	3.00e-95	340.00
IUUC-Apl-003611	Anas platyrhynchos	26.97	7.00e-31	126.00
IUUC-Aca-004411	Anolis carolinensis	27.27	6.00e-29	120.00
IUUC-Aly-005636	Arabidopsis lyrata	96.14	0.00e+00	627.00
IUUC-Ago-007978	Ashbya gossypii	22.67	2.00e-06	45.80
IUUC-Acl-008328	Aspergillus clavatus	34.15	4.00e-18	84.70
IUUC-Afl-008638	Aspergillus flavus	35.83	2.00e-28	119.00
IUUC-Afu-009042	Aspergillus fumigatus	35.11	3.00e-28	118.00
IUUC-Ani-009364	Aspergillus nidulans	37.22	1.00e-28	119.00
IUUC-Aor-009889	Aspergillus oryzae	35.83	2.00e-28	119.00
IUUC-Ate-010511	Aspergillus terreus	34.41	2.00e-09	53.50
IUUC-Ame-011644	Astyanax mexicanus	35.53	8.00e-08	47.40
IUUC-Bgr-012153	Blumeria graminis	30.95	1.00e-14	72.80
IUUC-Bta-012360	Bos taurus	34.39	1.00e-24	104.00
IUUC-Bci-013723	Botrytis cinerea	35.19	3.00e-18	84.70
IUUC-Bdi-014520	Brachypodium distachyon	52.62	1.00e-94	338.00
IUUC-Bol-016053	Brassica oleracea	86.31	2.00e-167	581.00
IUUC-Bra-017072	Brassica rapa	85.42	1.00e-166	578.00
IUUC-Cel-018529	Caenorhabditis elegans	27.96	9.00e-15	73.20
IUUC-Cja-019569	Callithrix jacchus	28.18	2.00e-31	128.00
IUUC-Cfa-020473	Canis familiaris	28.18	3.00e-31	128.00
IUUC-Cpo-021421	Cavia porcellus	27.58	7.00e-30	123.00
IUUC-Cre-022862	Chlamydomonas reinhardtii	36.47	1.00e-23	102.00
IUUC-Csa-024197	Chlorocebus sabaeus	27.88	6.00e-31	127.00
IUUC-Cho-024521	Choloepus hoffmanni	26.94	1.00e-24	105.00
IUUC-Cin-025119	Ciona intestinalis	30.81	1.00e-23	102.00
IUUC-Csv-026192	Ciona savignyi	25.61	6.00e-26	110.00
IUUC-Cgl-026686	Colletotrichum gloeosporioides	23.98	7.00e-09	53.50
IUUC-Dre-028466	Danio rerio	27.58	2.00e-30	125.00
IUUC-Dse-031228	Dothistroma septosporum	31.94	1.00e-24	106.00
IUUC-Dme-031703	Drosophila melanogaster	23.49	7.00e-22	96.70
IUUC-Ete-032482	Echinops telfairi	26.60	2.00e-24	105.00
IUUC-Eca-034036	Equus caballus	28.18	3.00e-31	127.00
IUUC-Eeu-035235	Erinaceus europaeus	34.39	4.00e-24	103.00
IUUC-Fca-036263	Felis catus	28.18	3.00e-31	127.00
IUUC-Fal-037064	Ficedula albicollis	27.27	5.00e-31	127.00
IUUC-Fox-037813	Fusarium oxysporum	29.38	7.00e-16	76.60
IUUC-Fso-038139	Fusarium solani	28.65	9.00e-15	73.20
IUUC-Gmo-039509	Gadus morhua	32.35	6.00e-26	110.00
IUUC-Ggr-040111	Gaeumannomyces graminis	30.49	1.00e-10	59.70
IUUC-Gga-040517	Gallus gallus	26.97	3.00e-30	124.00
IUUC-Gac-042270	Gasterosteus aculeatus	30.19	2.00e-25	108.00
IUUC-Gma-044400	Glycine max	67.14	3.00e-78	283.00
IUUC-Ggo-045048	Gorilla gorilla	28.18	9.00e-31	126.00
IUUC-Hsa-046744	Homo sapiens	28.18	2.00e-31	128.00
IUUC-Kpa-049174	Komagataella pastoris	25.41	6.00e-18	84.00
IUUC-Lch-049475	Latimeria chalumnae	26.28	3.00e-28	118.00
IUUC-Lpe-051283	Leersia perrieri	53.06	3.00e-96	345.00
IUUC-Loc-052446	Lepisosteus oculatus	27.58	6.00e-30	123.00
IUUC-Lma-053278	Leptosphaeria maculans	36.13	7.00e-26	110.00
IUUC-Laf-054020	Loxodonta africana	28.48	1.00e-31	129.00
IUUC-Mcc-055176	Macaca mulatta	28.18	2.00e-31	128.00
IUUC-Mor-057164	Magnaporthe oryzae	32.14	3.00e-17	81.60
IUUC-Mpo-057428	Magnaporthe poae	34.04	8.00e-10	57.00
IUUC-Mtr-058424	Medicago truncatula	65.73	3.00e-77	280.00
IUUC-Mla-058872	Melampsora laricipopulina	28.02	8.00e-13	67.40
IUUC-Mga-059859	Meleagris gallopavo	26.97	3.00e-30	124.00
IUUC-Mmr-061482	Microcebus murinus	28.18	4.00e-31	127.00
IUUC-Mdo-062371	Monodelphis domestica	27.88	7.00e-33	133.00
IUUC-Mmu-063139	Mus musculus	28.79	1.00e-31	129.00
IUUC-Mac-065332	Musa acuminata	53.61	6.00e-110	389.00
IUUC-Mpu-066783	Mustela putorius furo	27.88	1.00e-30	126.00
IUUC-Mlu-068165	Myotis lucifugus	28.48	5.00e-32	130.00
IUUC-Nfi-068578	Neosartorya fischeri	35.11	1.00e-28	119.00
IUUC-Ncr-068636	Neurospora crassa	31.14	5.00e-13	67.80
IUUC-Nle-069740	Nomascus leucogenys	28.18	2.00e-31	128.00
IUUC-Opr-070802	Ochotona princeps	34.39	8.00e-24	103.00
IUUC-Ont-072222	Oreochromis niloticus	28.18	6.00e-30	123.00
IUUC-Oan-072760	Ornithorhynchus anatinus	31.00	3.00e-28	117.00
IUUC-Ocu-074844	Oryctolagus cuniculus	22.17	2.00e-09	54.70
IUUC-Oba-075834	Oryza barthii	52.33	3.00e-102	364.00
IUUC-Obr-076230	Oryza brachyantha	49.11	2.00e-72	265.00
IUUC-Ogl-077554	Oryza glaberrima	52.33	3.00e-102	364.00
IUUC-Ogu-078687	Oryza glumaepatula	50.54	7.00e-100	356.00
IUUC-Oin-079677	Oryza indica	50.41	2.00e-98	351.00
IUUC-Olo-081078	Oryza longistaminata	51.66	2.00e-94	338.00
IUUC-Ome-081548	Oryza meridionalis	52.33	9.00e-104	370.00
IUUC-Oni-082050	Oryza nivara	52.05	1.00e-101	362.00
IUUC-Opu-083609	Oryza punctata	52.60	3.00e-103	367.00
IUUC-Oru-085057	Oryza rufipogon	52.05	6.00e-102	363.00
IUUC-Osa-085917	Oryza sativa	51.78	9.00e-101	359.00
IUUC-Ola-087032	Oryzias latipes	28.79	2.00e-30	125.00
IUUC-Olu-087877	Ostreococcus lucimarinus	28.57	2.90e-01	26.90
IUUC-Oga-088468	Otolemur garnettii	27.88	2.00e-32	131.00
IUUC-Oar-089751	Ovis aries	28.18	7.00e-31	126.00
IUUC-Ptr-091064	Pan troglodytes	28.18	2.00e-31	128.00
IUUC-Pan-092505	Papio anubis	28.79	3.00e-32	131.00
IUUC-Psi-093086	Pelodiscus sinensis	27.88	2.00e-31	128.00
IUUC-Pno-094825	Phaeosphaeria nodorum	35.85	6.00e-21	93.60
IUUC-Ppa-095419	Physcomitrella patens	38.64	2.00e-76	278.00
IUUC-Pfo-096224	Poecilia formosa	28.79	4.00e-30	124.00
IUUC-Pab-098501	Pongo abelii	28.18	6.00e-31	126.00
IUUC-Pop-099243	Populus trichocarpa	61.90	4.00e-115	407.00
IUUC-Ppe-101255	Prunus persica	62.53	5.00e-123	433.00
IUUC-Pva-102828	Pteropus vampyrus	28.48	8.00e-32	129.00
IUUC-Pgr-103672	Puccinia graminis	21.85	5.00e-12	64.70
IUUC-Ptt-104013	Puccinia triticina	26.74	4.00e-12	65.10
IUUC-Pyt-104615	Pyrenophora triticirepentis	33.50	5.00e-23	100.00
IUUC-Rno-106089	Rattus norvegicus	27.67	4.00e-25	107.00
IUUC-Sce-106216	Saccharomyces cerevisiae	24.67	8.00e-09	53.50
IUUC-Sha-106484	Sarcophilus harrisii	28.48	7.00e-34	136.00
IUUC-Sja-107699	Schizosaccharomyces japonicus	28.30	1.00e-22	99.40
IUUC-Spo-108177	Schizosaccharomyces pombe	25.36	5.00e-18	84.00
IUUC-Ssl-108475	Sclerotinia sclerotiorum	33.13	2.00e-17	82.40
IUUC-Smo-109473	Selaginella moellendorffii	41.64	4.00e-71	260.00
IUUC-Sit-110736	Setaria italica	52.60	2.00e-99	354.00
IUUC-Sly-111657	Solanum lycopersicum	53.09	4.00e-121	427.00
IUUC-Sar-113050	Sorex araneus	34.31	1.00e-21	96.30
IUUC-Sbi-114258	Sorghum bicolor	52.30	7.00e-102	363.00
IUUC-Sre-114902	Sporisorium reilianum	25.20	5.00e-18	85.10
IUUC-Ssc-116166	Sus scrofa	27.27	7.00e-29	120.00
IUUC-Tgu-116814	Taeniopygia guttata	27.27	8.00e-31	126.00
IUUC-Tru-118172	Takifugu rubripes	26.75	3.00e-29	120.00
IUUC-Tsy-119010	Tarsius syrichta	32.94	8.00e-27	113.00
IUUC-Tni-120397	Tetraodon nigroviridis	32.20	4.00e-26	110.00
IUUC-Tca-121283	Theobroma cacao	63.23	3.00e-127	447.00
IUUC-Tvi-122545	Trichoderma virens	28.40	1.00e-12	66.20
IUUC-Tae-122685	Triticum aestivum	56.38	5.00e-88	316.00
IUUC-Tur-126407	Triticum urartu	52.76	3.00e-95	340.00
IUUC-Tme-126913	Tuber melanosporum	31.35	3.00e-25	108.00
IUUC-Tbe-127738	Tupaia belangeri	25.20	6.00e-19	86.30
IUUC-Ttr-128528	Tursiops truncatus	27.88	7.00e-31	126.00
IUUC-Uma-129625	Ustilago maydis	24.42	8.00e-16	77.80
IUUC-Vda-129906	Verticillium dahliae	27.22	2.00e-09	55.10
IUUC-Vpa-130223	Vicugna pacos	27.58	6.00e-29	120.00
IUUC-Vvi-131617	Vitis vinifera	61.26	1.00e-124	439.00
IUUC-Xtr-132288	Xenopus tropicalis	27.58	2.00e-30	125.00
IUUC-Xma-134214	Xiphophorus maculatus	33.33	6.00e-26	109.00
IUUC-Yli-134377	Yarrowia lipolytica	25.81	8.00e-05	40.00
IUUC-Zma-135108	Zea mays	46.00	5.00e-90	323.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence