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Tag Content
UUCD2 ID IUUC-Ocu-074397
UUCD1 version UUC-OrC-00035
Ensembl Protein ID ENSOCUP00000000785.3
UniProt Accession G1SEB4; G1SEB4_RABIT
Genbank Protein ID ENSOCUP00000000785
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAGW02029600
Gene Name HACE1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOCUG00000000909.3 ENSOCUT00000000909.3 ENSOCUP00000000785.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 1.60e-117 392.7 573 902
Active Site
Position(s) Description Evidence
873 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           ++lk+ + v+f gEeg+++ Gv re+++ ls+e+ npd+ lf++s+ d +t+qpn++s++ np+hl++F+f+G++lg+al +++l+++ 
   Q: 573  AKLKQGIAVRFHGEEGMGQ-GVVREWFDILSNEIVNPDYALFTQSA-DGTTFQPNSNSYV-NPDHLNYFRFAGQILGLALNHRQLVNIY 658
           679999*************.**********************6666.67788*******9.89************************** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           +++sfyk++lg +++++d++++dpe++k+l++i++n   di++lgl+ltfsv+++++g ++e+ LkpgG +i Vt++Nk eYv+lv+e+
   Q: 659  FTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDN---DISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTEL 744
           **********************************99...************************************************** PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvT 269
           r+++ i+ q++af +Gf+  ip++l++lF+e elell++G++eidv+d+ k+t+y++gy++++ +iqwFwev+e++++eer  +LqFvT
   Q: 745  RMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDLVIQWFWEVVEDITQEERVLLLQFVT 833
           ***************************************************************************************** PP
   S: 270  gssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kg 332
           gssr+P+gGfa+++     + f+i     +++ lP+s+TC+n+LkLPeY+skeilk++Ll+A + +  g
   Q: 834  GSSRVPHGGFANIMggsgLQNFTIAAvPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGsYG 902
           ******************8888888868888********************************986555 PP
   
Organism Oryctolagus cuniculus
Protein Sequence
(Fasta)
MERAMEQLNR LTRSLRRART VELPEDNETA VYTLMPMVMA DQHRSVSELL SNSKFDVNYA 60
FGRVKRSLLH IAANCGSVEC LVLLLKKGAN PNYQDISGCT PLHLAARNGQ KKCMSKLLEY 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ocu-074397|E3,HECT|Oryctolagus cuniculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGAGAGAG CGATGGAGCA GCTCAACCGC CTGACTCGCT CGCTGCGCCG CGCGCGCACC 60
GTGGAGTTGC CCGAGGGTGA GCGGGGCCGC GGGGCTGGGG GCGACGCGGG GCGGCTCGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ocu-074397|E3,HECT|Oryctolagus cuniculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000569--HECT_dom
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50237--HECT
Pfam

PF12796--Ank_2
PF00632--HECT
PRINTS

PR01415--ANKYRIN
SMART

SM00248--ANK
SM00119--HECTc
Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0000139--C:Golgi membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0007030--P:Golgi organization
GO:0061025--P:membrane fusion
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030334--P:regulation of cell migration
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001490 Ailuropoda melanoleuca 85.93 0.00e+00 1580.00
IUUC-Apl-003400 Anas platyrhynchos 73.28 0.00e+00 920.00
IUUC-Aca-005375 Anolis carolinensis 81.99 0.00e+00 1518.00
IUUC-Ame-011847 Astyanax mexicanus 76.74 0.00e+00 1454.00
IUUC-Bta-012831 Bos taurus 85.35 0.00e+00 1536.00
IUUC-Cja-019160 Callithrix jacchus 86.67 0.00e+00 1599.00
IUUC-Cfa-020346 Canis familiaris 85.89 0.00e+00 1583.00
IUUC-Cpo-021766 Cavia porcellus 85.56 0.00e+00 1579.00
IUUC-Csa-023768 Chlorocebus sabaeus 86.43 0.00e+00 1599.00
IUUC-Cho-024688 Choloepus hoffmanni 78.91 0.00e+00 949.00
IUUC-Cin-025417 Ciona intestinalis 51.19 2.00e-121 430.00
IUUC-Csv-025993 Ciona savignyi 50.59 2.00e-118 420.00
IUUC-Dre-027819 Danio rerio 78.07 0.00e+00 1452.00
IUUC-Dno-029027 Dasypus novemcinctus 85.65 0.00e+00 1584.00
IUUC-Dor-030327 Dipodomys ordii 78.27 0.00e+00 1363.00
IUUC-Ete-032966 Echinops telfairi 79.34 0.00e+00 1450.00
IUUC-Eca-034339 Equus caballus 86.11 0.00e+00 1588.00
IUUC-Eeu-034544 Erinaceus europaeus 81.70 4.00e-148 518.00
IUUC-Fca-035617 Felis catus 80.86 0.00e+00 1049.00
IUUC-Fal-036687 Ficedula albicollis 81.31 0.00e+00 1541.00
IUUC-Gmo-039508 Gadus morhua 79.01 0.00e+00 735.00
IUUC-Gga-040845 Gallus gallus 81.31 0.00e+00 1548.00
IUUC-Gac-041894 Gasterosteus aculeatus 77.24 0.00e+00 1405.00
IUUC-Ggo-044465 Gorilla gorilla 82.77 0.00e+00 1517.00
IUUC-Hsa-045731 Homo sapiens 86.65 0.00e+00 1602.00
IUUC-Itr-048716 Ictidomys tridecemlineatus 86.43 0.00e+00 1593.00
IUUC-Lch-050436 Latimeria chalumnae 81.24 0.00e+00 1508.00
IUUC-Loc-052287 Lepisosteus oculatus 77.15 0.00e+00 1473.00
IUUC-Laf-053846 Loxodonta africana 86.56 0.00e+00 1601.00
IUUC-Mcc-055845 Macaca mulatta 86.54 0.00e+00 1600.00
IUUC-Meu-056060 Macropus eugenii 93.33 0.00e+00 658.00
IUUC-Mga-059935 Meleagris gallopavo 83.08 0.00e+00 1529.00
IUUC-Mmr-060960 Microcebus murinus 86.65 0.00e+00 1600.00
IUUC-Mdo-061851 Monodelphis domestica 82.26 0.00e+00 1562.00
IUUC-Mmu-063657 Mus musculus 85.56 0.00e+00 1584.00
IUUC-Mpu-066161 Mustela putorius furo 97.72 0.00e+00 813.00
IUUC-Mlu-067354 Myotis lucifugus 83.88 0.00e+00 1506.00
IUUC-Nle-069112 Nomascus leucogenys 86.54 0.00e+00 1598.00
IUUC-Opr-070686 Ochotona princeps 80.59 0.00e+00 723.00
IUUC-Ont-072398 Oreochromis niloticus 77.81 0.00e+00 1408.00
IUUC-Oan-073194 Ornithorhynchus anatinus 84.45 0.00e+00 1501.00
IUUC-Ola-086777 Oryzias latipes 74.60 0.00e+00 1413.00
IUUC-Oga-088684 Otolemur garnettii 86.34 0.00e+00 1592.00
IUUC-Oar-089428 Ovis aries 85.24 0.00e+00 1547.00
IUUC-Ptr-090529 Pan troglodytes 86.54 0.00e+00 1600.00
IUUC-Pan-091702 Papio anubis 86.54 0.00e+00 1600.00
IUUC-Psi-093969 Pelodiscus sinensis 80.83 0.00e+00 1480.00
IUUC-Pfo-097364 Poecilia formosa 78.63 0.00e+00 1433.00
IUUC-Pab-098574 Pongo abelii 86.65 0.00e+00 1602.00
IUUC-Pca-100525 Procavia capensis 87.15 7.00e-180 624.00
IUUC-Pva-102365 Pteropus vampyrus 78.24 0.00e+00 1402.00
IUUC-Rno-105153 Rattus norvegicus 84.64 0.00e+00 1576.00
IUUC-Sha-107319 Sarcophilus harrisii 82.37 0.00e+00 1558.00
IUUC-Sar-113449 Sorex araneus 96.10 1.00e-113 404.00
IUUC-Ssc-115865 Sus scrofa 86.00 0.00e+00 1583.00
IUUC-Tgu-117225 Taeniopygia guttata 81.41 0.00e+00 1551.00
IUUC-Tru-118026 Takifugu rubripes 75.59 0.00e+00 1387.00
IUUC-Tsy-119407 Tarsius syrichta 77.58 0.00e+00 1389.00
IUUC-Tni-120234 Tetraodon nigroviridis 75.64 0.00e+00 1084.00
IUUC-Tbe-127708 Tupaia belangeri 65.71 2.00e-172 599.00
IUUC-Ttr-128667 Tursiops truncatus 85.67 0.00e+00 1579.00
IUUC-Vpa-130200 Vicugna pacos 85.59 0.00e+00 1526.00
IUUC-Xtr-132176 Xenopus tropicalis 78.43 0.00e+00 1490.00
Created Date 25-Jun-2017

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