iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000010092.3	ENSMMUT00000014089.3	ENSMMUP00000013195.3
ENSMMUG00000010092.3	ENSMMUT00000014088.3	ENSMMUP00000013194.3
ENSMMUG00000010092.3	ENSMMUT00000055298.1	ENSMMUP00000044246.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.60e-07	30.5	21	61
E3 activity/RING/U-box	7.50e-09	36.6	16	85

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+C+++f+d  ++l+CgH f++ C+  +w     + + + +CP+C+
   Q: 21   CAVCYDPFRD-AVTLRCGHNFCRGCVsRCW-----EVQVSPTCPVCK 61
           ********99.999************9999.....799999*****6 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrliqawcee 71
            ee+lC++ ++++rd v+l +G+ + r ++ ++ + + + tcPv++ + ++ dl  n+tl +l+++ + e
   Q: 16   KEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSpTCPVCKDRASPADLRTNHTLNNLVEKLLRE 85
           689******************************97766669**********************9987765 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MERSPDVSPG PSRSFKEELL CAVCYDPFRD AVTLRCGHNF CRGCVSRCWE VQVSPTCPVC 60
KDRASPADLR TNHTLNNLVE KLLREEAEGA RWTSYRFSRV CRLHRGQLSL FCLEDKELLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAGACCTA CCGCGCCGCC TGGGAGACCC TTCCGTGCTA CCCAGGCCAG GGACCCGCCC 60
GGACCCGAGC AGGCGGGTAC TGCGGGCACA AGGCCGATCC CGCTCTCCCA GGATTTCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001788	Ailuropoda melanoleuca	88.98	0.00e+00	920.00
IUUC-Apl-003958	Anas platyrhynchos	52.35	4.00e-130	458.00
IUUC-Aca-005199	Anolis carolinensis	45.81	1.00e-120	426.00
IUUC-Ame-011964	Astyanax mexicanus	35.46	3.00e-69	256.00
IUUC-Bta-013359	Bos taurus	86.86	0.00e+00	880.00
IUUC-Cja-018900	Callithrix jacchus	80.83	0.00e+00	823.00
IUUC-Cfa-020685	Canis familiaris	88.78	0.00e+00	919.00
IUUC-Cpo-022253	Cavia porcellus	79.16	0.00e+00	785.00
IUUC-Csa-023777	Chlorocebus sabaeus	97.39	0.00e+00	1000.00
IUUC-Dre-027686	Danio rerio	33.62	2.00e-58	219.00
IUUC-Dno-029065	Dasypus novemcinctus	83.37	0.00e+00	872.00
IUUC-Dor-030248	Dipodomys ordii	61.71	3.00e-96	344.00
IUUC-Ete-033183	Echinops telfairi	72.55	0.00e+00	713.00
IUUC-Eca-033263	Equus caballus	87.58	0.00e+00	797.00
IUUC-Eeu-034699	Erinaceus europaeus	80.95	5.00e-112	398.00
IUUC-Fca-036366	Felis catus	87.37	0.00e+00	904.00
IUUC-Fal-037257	Ficedula albicollis	55.05	6.00e-152	530.00
IUUC-Gmo-038512	Gadus morhua	34.56	4.00e-67	248.00
IUUC-Gga-041125	Gallus gallus	52.72	3.00e-101	361.00
IUUC-Ggo-045233	Gorilla gorilla	95.96	0.00e+00	631.00
IUUC-Hsa-046042	Homo sapiens	97.39	0.00e+00	1000.00
IUUC-Itr-048751	Ictidomys tridecemlineatus	89.51	0.00e+00	900.00
IUUC-Laf-054322	Loxodonta africana	88.22	0.00e+00	890.00
IUUC-Meu-055900	Macropus eugenii	78.01	0.00e+00	783.00
IUUC-Mga-059380	Meleagris gallopavo	53.73	6.00e-100	357.00
IUUC-Mmr-061296	Microcebus murinus	91.98	0.00e+00	942.00
IUUC-Mdo-062811	Monodelphis domestica	78.05	0.00e+00	784.00
IUUC-Mmu-063718	Mus musculus	77.44	0.00e+00	787.00
IUUC-Mpu-066219	Mustela putorius furo	88.30	0.00e+00	889.00
IUUC-Mlu-067033	Myotis lucifugus	83.33	0.00e+00	865.00
IUUC-Nle-069806	Nomascus leucogenys	96.57	0.00e+00	926.00
IUUC-Opr-070248	Ochotona princeps	80.16	0.00e+00	777.00
IUUC-Ont-072083	Oreochromis niloticus	32.73	3.00e-70	259.00
IUUC-Oan-073364	Ornithorhynchus anatinus	67.59	2.00e-93	334.00
IUUC-Ocu-074572	Oryctolagus cuniculus	91.77	0.00e+00	946.00
IUUC-Oga-088378	Otolemur garnettii	87.58	0.00e+00	885.00
IUUC-Oar-089516	Ovis aries	86.19	0.00e+00	867.00
IUUC-Ptr-091313	Pan troglodytes	97.39	0.00e+00	1000.00
IUUC-Pan-092877	Papio anubis	97.60	0.00e+00	1001.00
IUUC-Psi-093928	Pelodiscus sinensis	57.82	6.00e-158	550.00
IUUC-Pfo-096690	Poecilia formosa	34.17	4.00e-68	251.00
IUUC-Pab-098624	Pongo abelii	96.99	0.00e+00	993.00
IUUC-Pca-100469	Procavia capensis	81.03	0.00e+00	818.00
IUUC-Pva-103227	Pteropus vampyrus	88.18	0.00e+00	912.00
IUUC-Rno-105778	Rattus norvegicus	77.24	0.00e+00	787.00
IUUC-Sha-107392	Sarcophilus harrisii	67.59	0.00e+00	669.00
IUUC-Sar-113297	Sorex araneus	72.09	3.00e-53	201.00
IUUC-Ssc-115739	Sus scrofa	87.27	0.00e+00	881.00
IUUC-Tru-117718	Takifugu rubripes	32.42	4.00e-64	238.00
IUUC-Tbe-127926	Tupaia belangeri	84.97	5.00e-136	477.00
IUUC-Ttr-129293	Tursiops truncatus	88.38	0.00e+00	906.00
IUUC-Vpa-130379	Vicugna pacos	87.50	9.00e-153	532.00
IUUC-Xma-134222	Xiphophorus maculatus	32.38	8.00e-61	228.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence