iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020025

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03007441

Gene Name

LONRF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000002239.3	ENSCAFT00000003510.2	ENSCAFP00000003254.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.10e-07	32.1	456	502
E3 activity/RING/RING	2.40e-06	28.3	459	497

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplte 52
           +f C++ + l  +Pv++p+G+t+  +++e++l++  + cP+++++l+e
   Q: 456  DFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPH-CPLCKEKLSE 502
           79***********************************.********76 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C+  +++ p+++pCgH+f+++Cl++          + +CPlC+
   Q: 459  CALCMRLLFE-PVTTPCGHTFCLKCLERC------LDHAPHCPLCK 497
           **********.9**************999......9*********6 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MSPEPVPPPP RPGGDCGEPL AQRLERADEA FRAGEYGAAA ELLRSALAGL AGLAGLAQPE 60
RGLCLRLGDA LARADRLPEA LGAFRGAARL GALRPEELGE LAGGLARALD RREGRLRAGR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTGGAATAT TGCATTTTAT TGCATTCACA GAATAAAATA AATGGTGAGA CACTAGGCCT 60
TATGTAGTGA AGAATTCTAA AAACTGGTTA ATGAGCACAG AAGGGAACAT TTAGTCCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg

SMART

SM00464--LON
SM00184--RING
SM00028--TPR

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001867	Ailuropoda melanoleuca	95.32	0.00e+00	1109.00
IUUC-Apl-003355	Anas platyrhynchos	63.41	0.00e+00	691.00
IUUC-Aca-004822	Anolis carolinensis	56.11	0.00e+00	753.00
IUUC-Acl-008224	Aspergillus clavatus	33.23	3.00e-39	156.00
IUUC-Afu-008802	Aspergillus fumigatus	31.51	2.00e-37	150.00
IUUC-Ame-010750	Astyanax mexicanus	47.96	0.00e+00	629.00
IUUC-Cja-019041	Callithrix jacchus	76.21	0.00e+00	1030.00
IUUC-Cre-022730	Chlamydomonas reinhardtii	29.03	1.00e-08	53.50
IUUC-Csa-023324	Chlorocebus sabaeus	86.07	0.00e+00	866.00
IUUC-Dre-028400	Danio rerio	51.20	5.00e-146	511.00
IUUC-Eeu-034779	Erinaceus europaeus	69.33	0.00e+00	671.00
IUUC-Fca-036276	Felis catus	94.82	0.00e+00	1115.00
IUUC-Fal-036669	Ficedula albicollis	61.96	0.00e+00	705.00
IUUC-Fox-037926	Fusarium oxysporum	24.22	4.00e-08	51.60
IUUC-Fso-038334	Fusarium solani	29.48	4.00e-40	159.00
IUUC-Gmo-039511	Gadus morhua	65.41	6.00e-117	414.00
IUUC-Gga-041253	Gallus gallus	59.62	0.00e+00	752.00
IUUC-Ggo-045501	Gorilla gorilla	83.06	0.00e+00	1115.00
IUUC-Hsa-046630	Homo sapiens	82.69	0.00e+00	1110.00
IUUC-Itr-048224	Ictidomys tridecemlineatus	82.32	0.00e+00	841.00
IUUC-Lch-049788	Latimeria chalumnae	49.34	0.00e+00	644.00
IUUC-Loc-051922	Lepisosteus oculatus	49.54	4.00e-180	624.00
IUUC-Laf-054421	Loxodonta africana	58.92	0.00e+00	773.00
IUUC-Mcc-054828	Macaca mulatta	85.86	0.00e+00	866.00
IUUC-Meu-055901	Macropus eugenii	54.93	1.00e-178	619.00
IUUC-Mtr-058075	Medicago truncatula	33.85	8.00e-42	164.00
IUUC-Mga-059760	Meleagris gallopavo	63.41	0.00e+00	693.00
IUUC-Mmr-061350	Microcebus murinus	79.73	0.00e+00	890.00
IUUC-Mdo-062203	Monodelphis domestica	59.40	0.00e+00	802.00
IUUC-Mmu-064118	Mus musculus	77.53	0.00e+00	778.00
IUUC-Mpu-065764	Mustela putorius furo	89.65	0.00e+00	1176.00
IUUC-Nle-069616	Nomascus leucogenys	83.38	0.00e+00	1120.00
IUUC-Ont-072142	Oreochromis niloticus	46.63	0.00e+00	630.00
IUUC-Oga-088972	Otolemur garnettii	83.68	0.00e+00	1086.00
IUUC-Ptr-090992	Pan troglodytes	87.57	0.00e+00	963.00
IUUC-Pan-092180	Papio anubis	81.72	0.00e+00	1096.00
IUUC-Psi-093423	Pelodiscus sinensis	63.06	0.00e+00	682.00
IUUC-Pfo-096363	Poecilia formosa	49.08	1.00e-179	623.00
IUUC-Pab-097974	Pongo abelii	82.41	0.00e+00	1106.00
IUUC-Pva-102269	Pteropus vampyrus	80.03	0.00e+00	1078.00
IUUC-Pgr-103289	Puccinia graminis	26.16	3.00e-26	113.00
IUUC-Rno-105905	Rattus norvegicus	79.84	0.00e+00	808.00
IUUC-Ssc-116224	Sus scrofa	74.04	0.00e+00	649.00
IUUC-Tgu-117000	Taeniopygia guttata	62.33	0.00e+00	732.00
IUUC-Tru-118016	Takifugu rubripes	48.60	1.00e-174	606.00
IUUC-Tni-119913	Tetraodon nigroviridis	47.02	4.00e-162	565.00
IUUC-Ttr-128666	Tursiops truncatus	80.89	0.00e+00	1081.00
IUUC-Uma-129541	Ustilago maydis	33.20	2.00e-34	141.00
IUUC-Vpa-130334	Vicugna pacos	69.64	0.00e+00	650.00
IUUC-Xtr-132065	Xenopus tropicalis	50.00	0.00e+00	678.00
IUUC-Xma-134324	Xiphophorus maculatus	49.01	1.00e-180	626.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence