iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054291

UUCD1 version

UUC-LoA-00403

Ensembl Protein ID

ENSLAFP00000009875.3

UniProt Accession

G3T884; G3T884_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TRIM50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000011816.3	ENSLAFT00000011817.3	ENSLAFP00000009875.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	7.50e-10	39.1	12	78
E3 activity/RING/RING	2.50e-08	34.7	16	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrss...IekwlasggktcPvtrqplteedlvPnltlrrliqaw 68
           + + CpI le++++P +l++G++y + +   + ++l+ + + cPv+rq +++++  Pn +l r+i+a 
   Q: 12   DRLQCPICLEVFKEPLMLQCGHSYCKGClvsLSRHLDADLR-CPVCRQAVDSSSSSPNVSLARVIEAL 78
           5689*********************9862225799999999.***********************985 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCle fk+ pl l+CgH +++ Cl   + l++      rCP+Cr
   Q: 16   CPICLEVFKE-PLMLQCGHSYCKGCL---VSLSRHLDADLRCPVCR 57
           ********99.999************...677899**********8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAWQVSVPEL EDRLQCPICL EVFKEPLMLQ CGHSYCKGCL VSLSRHLDAD LRCPVCRQAV 60
DSSSSSPNVS LARVIEALRL PRDPEPQVCV HHRNPLSIFC EEDQELICGL CGLLGSHQHH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGGC AGGTGAGTGT GCCAGAGCTG GAGGACCGGC TTCAGTGCCC CATCTGCCTA 60
GAGGTCTTTA AGGAGCCCCT GATGCTGCAG TGTGGCCACT CCTACTGTAA GGGCTGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0016235--C:aggresome
GO:0008270--F:zinc ion binding
GO:0070201--P:regulation of establishment of protein localization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001406	Ailuropoda melanoleuca	90.08	0.00e+00	890.00
IUUC-Apl-004051	Anas platyrhynchos	62.07	2.00e-173	602.00
IUUC-Ame-010964	Astyanax mexicanus	53.35	3.00e-153	535.00
IUUC-Bta-012642	Bos taurus	89.34	0.00e+00	862.00
IUUC-Cja-019011	Callithrix jacchus	86.48	0.00e+00	800.00
IUUC-Cfa-020270	Canis familiaris	89.26	0.00e+00	890.00
IUUC-Cpo-022458	Cavia porcellus	86.97	0.00e+00	835.00
IUUC-Csa-023478	Chlorocebus sabaeus	89.57	0.00e+00	858.00
IUUC-Dno-028894	Dasypus novemcinctus	87.31	0.00e+00	835.00
IUUC-Dor-030228	Dipodomys ordii	81.94	0.00e+00	707.00
IUUC-Eca-033497	Equus caballus	91.12	0.00e+00	905.00
IUUC-Eeu-034910	Erinaceus europaeus	74.00	8.00e-130	456.00
IUUC-Fca-036164	Felis catus	89.46	0.00e+00	887.00
IUUC-Gga-040573	Gallus gallus	55.44	2.00e-94	339.00
IUUC-Ggo-044471	Gorilla gorilla	90.62	0.00e+00	867.00
IUUC-Hsa-046039	Homo sapiens	90.62	0.00e+00	872.00
IUUC-Itr-048897	Ictidomys tridecemlineatus	88.50	0.00e+00	835.00
IUUC-Kpa-049137	Komagataella pastoris	40.00	4.00e-08	52.40
IUUC-Lch-050638	Latimeria chalumnae	54.96	4.00e-158	550.00
IUUC-Loc-051971	Lepisosteus oculatus	54.07	5.00e-153	533.00
IUUC-Mcc-055708	Macaca mulatta	89.57	0.00e+00	858.00
IUUC-Meu-056670	Macropus eugenii	70.03	7.00e-137	480.00
IUUC-Mga-059415	Meleagris gallopavo	60.78	3.00e-174	604.00
IUUC-Mmr-061410	Microcebus murinus	89.68	0.00e+00	835.00
IUUC-Mmu-064094	Mus musculus	85.71	0.00e+00	854.00
IUUC-Mpu-065781	Mustela putorius furo	89.05	0.00e+00	878.00
IUUC-Mlu-067974	Myotis lucifugus	88.72	0.00e+00	852.00
IUUC-Nle-069000	Nomascus leucogenys	90.41	0.00e+00	866.00
IUUC-Opr-071216	Ochotona princeps	87.91	4.00e-112	398.00
IUUC-Ocu-074859	Oryctolagus cuniculus	86.67	0.00e+00	834.00
IUUC-Oga-088285	Otolemur garnettii	87.34	0.00e+00	854.00
IUUC-Oar-090161	Ovis aries	81.49	0.00e+00	763.00
IUUC-Ptr-091672	Pan troglodytes	90.62	0.00e+00	869.00
IUUC-Pan-092870	Papio anubis	89.79	0.00e+00	859.00
IUUC-Psi-093742	Pelodiscus sinensis	63.52	0.00e+00	645.00
IUUC-Pab-098034	Pongo abelii	90.62	0.00e+00	870.00
IUUC-Pca-100115	Procavia capensis	86.67	2.00e-73	269.00
IUUC-Pva-103234	Pteropus vampyrus	89.55	0.00e+00	861.00
IUUC-Rno-105163	Rattus norvegicus	86.13	0.00e+00	840.00
IUUC-Sha-106575	Sarcophilus harrisii	63.84	1.00e-156	546.00
IUUC-Ssc-115600	Sus scrofa	89.26	0.00e+00	879.00
IUUC-Tbe-128151	Tupaia belangeri	89.13	6.00e-93	332.00
IUUC-Ttr-128947	Tursiops truncatus	90.04	0.00e+00	851.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence