iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027511

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

F-box and WD repeat domain-containing 5; F-box and WD-40 domain protein 5

Genbank Nucleotide ID

BX294186

Gene Name

fbxw5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000099139.1	ENSDART00000165719.1	ENSDARP00000141973.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-15	56.6	530	561

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +H d v+++af   d  ll+s+sdD tikvW+
   Q: 530  QHDDVVNSVAFspADqELLLSASDDSTIKVWR 561
           59**********9667***************8 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MASGPGLPDS LVLEIFLHLP HKAVLSAGLT CHQWFAVSRD EFLWKELFYS YYRIPRTVPR 60
HPAAVSWYRE FKRLYDCIPC VEVQTLKEHH DQVLHLAFSH RGHRFSSCSK DCTVKLWDTE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGATTGAG CTAGTCGCAT AACCGGAGCT GAAACAATTT GAAGATAAAT TAAAACTAGC 60
TCTTTATACC ACTAGCTGTG GCCTTTGGCA GGTAATGTAC AATTTGTTTA AGCATTTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0000151--C:ubiquitin ligase complex
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0010824--P:regulation of centrosome duplication
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

dre:406611

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001942	Ailuropoda melanoleuca	66.49	0.00e+00	748.00
IUUC-Apl-003274	Anas platyrhynchos	71.60	0.00e+00	711.00
IUUC-Aca-004626	Anolis carolinensis	54.43	6.00e-91	327.00
IUUC-Ame-011823	Astyanax mexicanus	78.30	0.00e+00	806.00
IUUC-Bta-012523	Bos taurus	67.72	0.00e+00	773.00
IUUC-Cja-018729	Callithrix jacchus	67.06	0.00e+00	781.00
IUUC-Cfa-020303	Canis familiaris	66.04	0.00e+00	780.00
IUUC-Cpo-022134	Cavia porcellus	67.66	0.00e+00	775.00
IUUC-Csa-023253	Chlorocebus sabaeus	68.51	0.00e+00	798.00
IUUC-Cin-025742	Ciona intestinalis	33.95	4.00e-81	295.00
IUUC-Dno-029044	Dasypus novemcinctus	67.07	0.00e+00	771.00
IUUC-Dor-030565	Dipodomys ordii	67.68	0.00e+00	778.00
IUUC-Dme-031713	Drosophila melanogaster	40.95	1.00e-125	443.00
IUUC-Eca-033709	Equus caballus	68.25	0.00e+00	780.00
IUUC-Eeu-035093	Erinaceus europaeus	82.39	4.00e-79	288.00
IUUC-Fca-035674	Felis catus	67.07	0.00e+00	776.00
IUUC-Fal-037104	Ficedula albicollis	70.57	0.00e+00	762.00
IUUC-Gmo-039041	Gadus morhua	74.08	0.00e+00	801.00
IUUC-Gga-041230	Gallus gallus	70.63	0.00e+00	808.00
IUUC-Gac-042594	Gasterosteus aculeatus	74.92	0.00e+00	809.00
IUUC-Ggo-044486	Gorilla gorilla	67.57	0.00e+00	764.00
IUUC-Hsa-045701	Homo sapiens	67.40	0.00e+00	764.00
IUUC-Itr-048811	Ictidomys tridecemlineatus	67.80	0.00e+00	795.00
IUUC-Lch-050058	Latimeria chalumnae	68.39	0.00e+00	794.00
IUUC-Loc-052525	Lepisosteus oculatus	76.96	0.00e+00	819.00
IUUC-Laf-054120	Loxodonta africana	67.89	0.00e+00	776.00
IUUC-Mcc-054915	Macaca mulatta	68.62	0.00e+00	780.00
IUUC-Meu-056715	Macropus eugenii	64.47	0.00e+00	742.00
IUUC-Mga-059831	Meleagris gallopavo	70.39	0.00e+00	722.00
IUUC-Mmr-060655	Microcebus murinus	67.60	0.00e+00	780.00
IUUC-Mdo-062641	Monodelphis domestica	69.83	0.00e+00	786.00
IUUC-Mmu-063471	Mus musculus	68.23	0.00e+00	786.00
IUUC-Mpu-066586	Mustela putorius furo	68.25	0.00e+00	779.00
IUUC-Nle-069429	Nomascus leucogenys	67.99	0.00e+00	791.00
IUUC-Ont-071780	Oreochromis niloticus	82.70	0.00e+00	890.00
IUUC-Ola-086458	Oryzias latipes	78.77	0.00e+00	904.00
IUUC-Oga-088739	Otolemur garnettii	67.94	0.00e+00	786.00
IUUC-Oar-089275	Ovis aries	72.09	9.00e-37	144.00
IUUC-Ptr-090716	Pan troglodytes	67.41	0.00e+00	632.00
IUUC-Pan-092182	Papio anubis	62.48	0.00e+00	683.00
IUUC-Psi-093449	Pelodiscus sinensis	69.35	0.00e+00	798.00
IUUC-Pma-094289	Petromyzon marinus	63.20	1.00e-100	360.00
IUUC-Pfo-096062	Poecilia formosa	84.39	0.00e+00	927.00
IUUC-Pab-098726	Pongo abelii	67.59	0.00e+00	773.00
IUUC-Pca-100163	Procavia capensis	66.84	2.00e-71	263.00
IUUC-Pva-103051	Pteropus vampyrus	74.06	4.00e-105	375.00
IUUC-Rno-105707	Rattus norvegicus	66.84	0.00e+00	771.00
IUUC-Sha-107074	Sarcophilus harrisii	69.77	0.00e+00	761.00
IUUC-Ssc-116020	Sus scrofa	66.80	0.00e+00	639.00
IUUC-Tgu-116683	Taeniopygia guttata	66.08	2.00e-90	325.00
IUUC-Tru-118143	Takifugu rubripes	79.77	0.00e+00	893.00
IUUC-Tni-120777	Tetraodon nigroviridis	78.95	0.00e+00	893.00
IUUC-Ttr-128439	Tursiops truncatus	67.37	0.00e+00	770.00
IUUC-Xtr-132774	Xenopus tropicalis	54.03	2.00e-137	482.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence