iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000000937.2	ENSPPYT00000032906.1	ENSPPYP00000023638.1
ENSPPYG00000000937.2	ENSPPYT00000001127.1	ENSPPYP00000001090.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.20e-09	37.8	228	269

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+ed+  +++++ lpC+H+fh +C+  w         +++CP+Cr
   Q: 228  CPVCKEDYtvEEEVRQLPCNHFFHSSCIVPW------LELHDTCPVCR 269
           ********99777******************......**********8 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAEASAAGAD SGAAVAAHRF FCHFCKGEVS PKLPEYICPR CESGFIEEVT DDSSFLGGGG 60
SRIDNSTTTH FAELWGHLDH TMFFQDFRPF LSSNPLDQDN RANERGHQTH TDFWGARPPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTAGCTCTA CACTCCCTTT ACACAGGTTC CCCTTTCTGA CTTGGTCTCT TGGTCCAGTC 60
AGTGCCGCCA CGTTCAGACA GCATTTTCCA CTAACCTCAG GGTCAGCGCA ATCCGGAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

KEGG

pon:100431951

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000079	Aegilops tauschii	30.69	6.00e-25	107.00
IUUC-Aml-002035	Ailuropoda melanoleuca	94.44	3.00e-149	520.00
IUUC-Atr-002522	Amborella trichopoda	40.19	7.00e-24	103.00
IUUC-Apl-003694	Anas platyrhynchos	89.16	1.00e-79	289.00
IUUC-Aca-004365	Anolis carolinensis	77.98	7.00e-44	168.00
IUUC-Aly-006495	Arabidopsis lyrata	29.28	1.00e-19	90.10
IUUC-Ath-007616	Arabidopsis thaliana	31.18	2.00e-25	109.00
IUUC-Acl-008247	Aspergillus clavatus	37.33	2.00e-19	89.70
IUUC-Afl-008423	Aspergillus flavus	41.58	9.00e-18	84.70
IUUC-Afu-008920	Aspergillus fumigatus	40.59	4.00e-17	82.40
IUUC-Ani-009396	Aspergillus nidulans	33.10	2.00e-16	80.10
IUUC-Ang-009638	Aspergillus niger	36.15	1.00e-14	74.30
IUUC-Aor-009896	Aspergillus oryzae	41.58	9.00e-18	84.70
IUUC-Ate-010398	Aspergillus terreus	38.66	1.00e-18	87.80
IUUC-Ame-011898	Astyanax mexicanus	52.41	9.00e-72	263.00
IUUC-Bgr-012144	Blumeria graminis	38.10	3.00e-18	86.70
IUUC-Bta-013190	Bos taurus	81.94	7.00e-122	429.00
IUUC-Bci-013958	Botrytis cinerea	37.14	2.00e-17	84.30
IUUC-Bdi-014137	Brachypodium distachyon	43.36	2.00e-23	102.00
IUUC-Bol-016085	Brassica oleracea	41.18	5.00e-28	119.00
IUUC-Bra-016939	Brassica rapa	31.79	2.00e-28	119.00
IUUC-Cel-018216	Caenorhabditis elegans	44.62	3.00e-14	72.40
IUUC-Cja-020001	Callithrix jacchus	95.47	2.00e-151	528.00
IUUC-Cfa-020882	Canis familiaris	94.43	1.00e-148	519.00
IUUC-Cpo-021690	Cavia porcellus	80.94	3.00e-115	407.00
IUUC-Csa-024004	Chlorocebus sabaeus	99.30	8.00e-155	539.00
IUUC-Cho-024643	Choloepus hoffmanni	92.55	3.00e-80	291.00
IUUC-Cin-025452	Ciona intestinalis	39.50	6.00e-19	86.30
IUUC-Csv-025892	Ciona savignyi	36.51	6.00e-21	92.80
IUUC-Cgl-026759	Colletotrichum gloeosporioides	33.00	6.00e-15	75.50
IUUC-Cne-026837	Cryptococcus neoformans	36.84	4.00e-16	79.70
IUUC-Dre-027515	Danio rerio	58.68	2.00e-81	295.00
IUUC-Dno-029010	Dasypus novemcinctus	93.75	2.00e-148	517.00
IUUC-Dor-030147	Dipodomys ordii	84.87	1.00e-128	451.00
IUUC-Dse-031376	Dothistroma septosporum	33.57	1.00e-17	84.30
IUUC-Dme-031601	Drosophila melanogaster	54.55	8.00e-35	140.00
IUUC-Ete-032392	Echinops telfairi	90.06	1.00e-78	285.00
IUUC-Eca-033803	Equus caballus	93.36	2.00e-136	478.00
IUUC-Eeu-034831	Erinaceus europaeus	74.74	8.00e-96	343.00
IUUC-Fca-036192	Felis catus	93.40	4.00e-156	543.00
IUUC-Fso-038447	Fusarium solani	34.00	5.00e-14	72.80
IUUC-Gmo-039513	Gadus morhua	59.12	2.00e-88	318.00
IUUC-Gga-040282	Gallus gallus	79.41	3.00e-76	276.00
IUUC-Gma-044015	Glycine max	31.25	2.00e-27	115.00
IUUC-Ggo-044873	Gorilla gorilla	99.30	2.00e-154	537.00
IUUC-Hsa-045780	Homo sapiens	99.30	8.00e-155	539.00
IUUC-Hvu-047602	Hordeum vulgare	43.27	1.00e-22	100.00
IUUC-Itr-048142	Ictidomys tridecemlineatus	92.62	3.00e-139	487.00
IUUC-Lch-050673	Latimeria chalumnae	75.78	4.00e-122	430.00
IUUC-Lpe-051427	Leersia perrieri	45.22	9.00e-25	107.00
IUUC-Lma-053066	Leptosphaeria maculans	36.13	9.00e-21	95.10
IUUC-Laf-054384	Loxodonta africana	88.19	7.00e-138	483.00
IUUC-Mcc-055137	Macaca mulatta	99.30	8.00e-155	539.00
IUUC-Meu-056635	Macropus eugenii	85.98	7.00e-113	399.00
IUUC-Mor-057098	Magnaporthe oryzae	38.71	4.00e-12	66.60
IUUC-Mtr-058295	Medicago truncatula	30.03	4.00e-24	105.00
IUUC-Mla-058832	Melampsora laricipopulina	46.84	9.00e-15	72.80
IUUC-Mvi-060434	Microbotryum violaceum	41.12	3.00e-18	86.30
IUUC-Mmr-060631	Microcebus murinus	95.49	1.00e-159	555.00
IUUC-Mdo-062489	Monodelphis domestica	87.50	3.00e-127	447.00
IUUC-Mmu-064196	Mus musculus	93.75	8.00e-157	545.00
IUUC-Mac-065133	Musa acuminata	44.25	2.00e-26	112.00
IUUC-Mpu-066575	Mustela putorius furo	94.44	2.00e-157	547.00
IUUC-Mlu-067024	Myotis lucifugus	87.08	2.00e-136	478.00
IUUC-Nfi-068352	Neosartorya fischeri	38.61	1.00e-16	80.90
IUUC-Ncr-068908	Neurospora crassa	31.51	7.00e-18	85.50
IUUC-Nle-069348	Nomascus leucogenys	98.26	5.00e-151	526.00
IUUC-Opr-070812	Ochotona princeps	86.81	3.00e-142	497.00
IUUC-Ont-072238	Oreochromis niloticus	46.84	2.00e-61	228.00
IUUC-Ocu-074691	Oryctolagus cuniculus	95.49	2.00e-146	511.00
IUUC-Oba-075047	Oryza barthii	46.02	4.00e-25	108.00
IUUC-Obr-076829	Oryza brachyantha	47.12	2.00e-24	106.00
IUUC-Ogl-077378	Oryza glaberrima	46.02	5.00e-25	107.00
IUUC-Ogu-078709	Oryza glumaepatula	46.02	4.00e-25	108.00
IUUC-Oin-079595	Oryza indica	50.00	3.00e-21	97.40
IUUC-Olo-080762	Oryza longistaminata	46.02	4.00e-25	108.00
IUUC-Ome-081151	Oryza meridionalis	48.48	8.00e-23	100.00
IUUC-Oni-083090	Oryza nivara	46.02	4.00e-25	108.00
IUUC-Opu-083898	Oryza punctata	46.02	2.00e-24	106.00
IUUC-Oru-084267	Oryza rufipogon	46.09	3.00e-25	108.00
IUUC-Osa-086229	Oryza sativa	46.02	4.00e-25	108.00
IUUC-Ola-087047	Oryzias latipes	61.38	3.00e-90	324.00
IUUC-Oga-089111	Otolemur garnettii	93.43	8.00e-141	492.00
IUUC-Oar-089999	Ovis aries	81.94	2.00e-122	432.00
IUUC-Ptr-091473	Pan troglodytes	98.95	6.00e-154	536.00
IUUC-Pan-092618	Papio anubis	85.71	4.00e-125	440.00
IUUC-Psi-093930	Pelodiscus sinensis	81.38	1.00e-113	402.00
IUUC-Pma-094530	Petromyzon marinus	47.19	3.00e-59	221.00
IUUC-Pno-094903	Phaeosphaeria nodorum	41.88	6.00e-18	85.50
IUUC-Ppa-095942	Physcomitrella patens	33.13	2.00e-21	96.70
IUUC-Pfo-096461	Poecilia formosa	69.09	1.00e-64	239.00
IUUC-Pop-099462	Populus trichocarpa	45.45	2.00e-23	102.00
IUUC-Pca-100550	Procavia capensis	73.61	1.00e-106	379.00
IUUC-Ppe-101439	Prunus persica	41.22	2.00e-22	99.40
IUUC-Pva-102881	Pteropus vampyrus	90.28	3.00e-143	500.00
IUUC-Pgr-103273	Puccinia graminis	37.29	1.00e-14	73.90
IUUC-Ptt-103768	Puccinia triticina	35.04	9.00e-13	68.60
IUUC-Pte-104223	Pyrenophora teres	39.50	1.00e-19	91.70
IUUC-Pyt-104653	Pyrenophora triticirepentis	38.64	4.00e-20	92.40
IUUC-Rno-104914	Rattus norvegicus	94.10	3.00e-157	547.00
IUUC-Sha-107616	Sarcophilus harrisii	87.45	5.00e-115	406.00
IUUC-Sja-107922	Schizosaccharomyces japonicus	41.04	6.00e-24	105.00
IUUC-Spo-108354	Schizosaccharomyces pombe	36.08	3.00e-26	113.00
IUUC-Ssl-108600	Sclerotinia sclerotiorum	32.43	7.00e-12	65.90
IUUC-Smo-109522	Selaginella moellendorffii	51.43	5.00e-20	88.60
IUUC-Sit-110648	Setaria italica	47.27	1.00e-25	109.00
IUUC-Sly-111407	Solanum lycopersicum	29.01	3.00e-24	105.00
IUUC-Stu-112467	Solanum tuberosum	27.99	1.00e-23	103.00
IUUC-Sar-113319	Sorex araneus	70.37	3.00e-61	228.00
IUUC-Sbi-114297	Sorghum bicolor	47.27	2.00e-25	109.00
IUUC-Sre-115230	Sporisorium reilianum	38.79	9.00e-18	85.10
IUUC-Ssc-115917	Sus scrofa	83.33	2.00e-127	448.00
IUUC-Tgu-117105	Taeniopygia guttata	90.55	4.00e-67	246.00
IUUC-Tru-118087	Takifugu rubripes	48.71	2.00e-60	225.00
IUUC-Tsy-119630	Tarsius syrichta	84.56	5.00e-133	466.00
IUUC-Tni-120265	Tetraodon nigroviridis	63.79	8.00e-95	339.00
IUUC-Tca-121480	Theobroma cacao	43.27	5.00e-24	104.00
IUUC-Tre-122013	Trichoderma reesei	36.54	5.00e-16	79.30
IUUC-Tvi-122598	Trichoderma virens	36.45	4.00e-16	79.30
IUUC-Tae-124758	Triticum aestivum	49.50	8.00e-22	97.40
IUUC-Tur-125986	Triticum urartu	30.35	1.00e-23	104.00
IUUC-Tme-127143	Tuber melanosporum	47.75	4.00e-28	118.00
IUUC-Tbe-127794	Tupaia belangeri	72.11	4.00e-95	340.00
IUUC-Ttr-129117	Tursiops truncatus	81.25	3.00e-116	410.00
IUUC-Uma-129414	Ustilago maydis	36.67	9.00e-18	85.10
IUUC-Vda-129671	Verticillium dahliae	35.00	2.00e-14	74.30
IUUC-Vpa-130755	Vicugna pacos	80.44	7.00e-110	389.00
IUUC-Vvi-131335	Vitis vinifera	29.53	5.00e-24	104.00
IUUC-Xtr-132520	Xenopus tropicalis	72.99	1.00e-96	345.00
IUUC-Xma-133074	Xiphophorus maculatus	68.48	4.00e-64	238.00
IUUC-Zma-135464	Zea mays	44.74	2.00e-24	106.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence