iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-134133

Ensembl Protein ID

ENSXMAP00000014582.1

UniProt Accession

M4AJD8; M4AJD8_XIPMA

Genbank Protein ID

ENSXMAP00000014582

Protein Name

Katanin p80 WD40 repeat-containing subunit B1; p80 katanin

Genbank Nucleotide ID

AGAJ01038819

Gene Name

katnb1; KATNB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000014543.1	ENSXMAT00000014602.1	ENSXMAP00000014582.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.10e-41	136.7	145	180
UBD/Beta-Prp	1.40e-79	267.4	62	281

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gHtd v++laf +d + l+s+sdD+t+k+WDl +g+
   Q: 145  GHTDAVRSLAFsPDgKWLASASDDCTVKLWDLFQGK 180
           8***********999****************98876 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           hk+++ cv+fs +++++a+gs++g+i+vwd++  k lr+l gh+a +t + f+p g++l+++s D +ik+wd++   +v  +kgh+d v
   Q: 62   HKNPVECVQFSVSEEQVAAGSQSGSIRVWDLEAAKILRTLMGHKANITGLGFHPFGNFLASSSVDTNIKLWDVRRKGYVFRYKGHTDAV 150
           899************************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysl 186
           +sl+fsp+g++l+s+s+d t+++wdl +g+ +   ++ h+++v  v++hp++ ll+sGs Dr ++lWdl+  + +  l+g +t++v++l
   Q: 151  RSLAFSPDGKWLASASDDCTVKLWDLFQGKTIT-EFKSHSAAVGAVQFHPNEYLLASGSVDRSIKLWDLEKFTRVGSLEG-DTSAVRCL 237
           ********************************9.*********************************************9.******** PP
   S: 187  sfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs 231
            f+++g +l sg+ d+ ++++  +  +c +t+      v++++++
   Q: 238  LFSPDGSCLYSGASDS-LRVFGWEPDRCFDTVPVGWGKVSDLAVC 281
           *************995.7777777777777776666666666666 PP

Organism

Xiphophorus maculatus

Functional Description
(View)

Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.

Protein Sequence
(Fasta)

MAAASSTKIS WRLQEFEAHS RTVSCLSLGK NSGRLLATGG EDCRVNIWAV SKANCVMSLT 60
GHKNPVECVQ FSVSEEQVAA GSQSGSIRVW DLEAAKILRT LMGHKANITG LGFHPFGNFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTAATTAA CTCGTATTGA TTAAATAATT AGATTTTCTC CGTTTGTTCG CTGAATTCAT 60
TGTTAATAAA GTTGGACAGA AAAATGCTAG TTTTTTACGT TAGCGGAAGT GACGTATTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0051013--P:microtubule severing
GO:0030901--P:midbrain development
GO:0007067--P:mitotic nuclear division

KEGG

xma:102231123

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000954	Aegilops tauschii	45.79	2.00e-76	281.00
IUUC-Aml-002187	Ailuropoda melanoleuca	55.79	0.00e+00	690.00
IUUC-Atr-002899	Amborella trichopoda	51.03	1.00e-93	337.00
IUUC-Apl-003305	Anas platyrhynchos	56.88	0.00e+00	766.00
IUUC-Aca-004635	Anolis carolinensis	59.30	0.00e+00	741.00
IUUC-Aly-005711	Arabidopsis lyrata	51.50	2.00e-97	350.00
IUUC-Ath-007606	Arabidopsis thaliana	51.50	2.00e-97	350.00
IUUC-Ame-010870	Astyanax mexicanus	61.37	5.00e-106	377.00
IUUC-Bta-012527	Bos taurus	57.77	0.00e+00	751.00
IUUC-Bdi-014652	Brachypodium distachyon	47.62	2.00e-96	347.00
IUUC-Bol-016374	Brassica oleracea	50.99	9.00e-97	348.00
IUUC-Bra-017390	Brassica rapa	49.37	2.00e-96	347.00
IUUC-Cja-019706	Callithrix jacchus	58.50	0.00e+00	698.00
IUUC-Cfa-020139	Canis familiaris	50.86	1.00e-137	483.00
IUUC-Cpo-021710	Cavia porcellus	58.14	0.00e+00	737.00
IUUC-Cre-022746	Chlamydomonas reinhardtii	39.67	5.00e-65	242.00
IUUC-Csa-023546	Chlorocebus sabaeus	58.02	0.00e+00	676.00
IUUC-Cin-025156	Ciona intestinalis	35.29	3.00e-127	449.00
IUUC-Csv-025962	Ciona savignyi	44.17	6.00e-76	277.00
IUUC-Dre-028215	Danio rerio	64.17	0.00e+00	863.00
IUUC-Dno-029314	Dasypus novemcinctus	56.25	0.00e+00	708.00
IUUC-Dor-030482	Dipodomys ordii	57.85	0.00e+00	754.00
IUUC-Dme-032188	Drosophila melanogaster	39.74	1.00e-61	231.00
IUUC-Eca-034143	Equus caballus	57.70	0.00e+00	735.00
IUUC-Fca-035924	Felis catus	58.94	0.00e+00	742.00
IUUC-Fal-037387	Ficedula albicollis	57.80	0.00e+00	770.00
IUUC-Gmo-038692	Gadus morhua	66.27	1.00e-161	563.00
IUUC-Gga-040597	Gallus gallus	58.76	0.00e+00	803.00
IUUC-Gac-042004	Gasterosteus aculeatus	72.73	0.00e+00	1025.00
IUUC-Gma-044134	Glycine max	51.83	2.00e-95	343.00
IUUC-Ggo-044761	Gorilla gorilla	58.45	0.00e+00	696.00
IUUC-Hsa-045698	Homo sapiens	58.45	0.00e+00	716.00
IUUC-Hvu-047649	Hordeum vulgare	50.00	1.00e-95	344.00
IUUC-Itr-048697	Ictidomys tridecemlineatus	57.93	0.00e+00	718.00
IUUC-Lch-049674	Latimeria chalumnae	58.25	0.00e+00	790.00
IUUC-Lpe-051554	Leersia perrieri	51.32	1.00e-97	351.00
IUUC-Loc-052623	Lepisosteus oculatus	65.02	0.00e+00	880.00
IUUC-Laf-054587	Loxodonta africana	57.43	0.00e+00	759.00
IUUC-Mcc-055851	Macaca mulatta	58.45	0.00e+00	696.00
IUUC-Meu-056704	Macropus eugenii	58.61	0.00e+00	805.00
IUUC-Mtr-058053	Medicago truncatula	51.83	1.00e-98	353.00
IUUC-Mga-059608	Meleagris gallopavo	58.27	0.00e+00	799.00
IUUC-Mmr-061154	Microcebus murinus	57.97	0.00e+00	718.00
IUUC-Mdo-062365	Monodelphis domestica	57.35	0.00e+00	758.00
IUUC-Mmu-063754	Mus musculus	55.43	0.00e+00	726.00
IUUC-Mac-064667	Musa acuminata	45.50	3.00e-96	345.00
IUUC-Mpu-066245	Mustela putorius furo	59.27	0.00e+00	719.00
IUUC-Mlu-067692	Myotis lucifugus	58.81	0.00e+00	727.00
IUUC-Nle-070051	Nomascus leucogenys	56.54	0.00e+00	691.00
IUUC-Opr-070855	Ochotona princeps	57.56	0.00e+00	727.00
IUUC-Ont-071883	Oreochromis niloticus	75.60	0.00e+00	1073.00
IUUC-Oan-073293	Ornithorhynchus anatinus	58.80	0.00e+00	706.00
IUUC-Ocu-074644	Oryctolagus cuniculus	58.28	0.00e+00	736.00
IUUC-Oba-075448	Oryza barthii	50.66	3.00e-96	346.00
IUUC-Obr-076385	Oryza brachyantha	50.66	1.00e-96	348.00
IUUC-Ogl-077427	Oryza glaberrima	50.66	2.00e-96	347.00
IUUC-Ogu-078062	Oryza glumaepatula	45.48	6.00e-86	312.00
IUUC-Oin-079811	Oryza indica	50.85	7.00e-94	338.00
IUUC-Olo-080245	Oryza longistaminata	50.85	7.00e-94	338.00
IUUC-Ome-081239	Oryza meridionalis	51.02	1.00e-93	338.00
IUUC-Oni-082640	Oryza nivara	50.66	3.00e-96	346.00
IUUC-Opu-083748	Oryza punctata	50.99	8.00e-97	348.00
IUUC-Oru-084609	Oryza rufipogon	50.66	3.00e-96	346.00
IUUC-Osa-085801	Oryza sativa	46.31	4.00e-87	316.00
IUUC-Ola-087483	Oryzias latipes	71.69	0.00e+00	845.00
IUUC-Oga-087964	Otolemur garnettii	57.92	0.00e+00	740.00
IUUC-Oar-089483	Ovis aries	56.57	0.00e+00	716.00
IUUC-Ptr-091387	Pan troglodytes	58.45	0.00e+00	716.00
IUUC-Pan-092623	Papio anubis	58.45	0.00e+00	696.00
IUUC-Psi-093830	Pelodiscus sinensis	57.39	0.00e+00	780.00
IUUC-Pma-094135	Petromyzon marinus	41.32	6.00e-37	147.00
IUUC-Ppa-095379	Physcomitrella patens	51.69	7.00e-90	325.00
IUUC-Pfo-096755	Poecilia formosa	97.37	0.00e+00	1325.00
IUUC-Pab-097564	Pongo abelii	57.49	1.00e-177	616.00
IUUC-Pop-099149	Populus trichocarpa	51.50	2.00e-98	353.00
IUUC-Pca-100357	Procavia capensis	69.52	2.00e-87	316.00
IUUC-Ppe-101237	Prunus persica	51.83	6.00e-98	352.00
IUUC-Pva-102397	Pteropus vampyrus	56.41	0.00e+00	683.00
IUUC-Rno-105349	Rattus norvegicus	58.14	0.00e+00	749.00
IUUC-Smo-109409	Selaginella moellendorffii	50.86	3.00e-91	329.00
IUUC-Sit-110360	Setaria italica	50.99	1.00e-96	348.00
IUUC-Sly-111307	Solanum lycopersicum	50.99	1.00e-94	341.00
IUUC-Stu-112462	Solanum tuberosum	51.19	9.00e-92	330.00
IUUC-Sar-112953	Sorex araneus	58.77	1.00e-74	274.00
IUUC-Sbi-114389	Sorghum bicolor	44.97	2.00e-85	310.00
IUUC-Ssc-115949	Sus scrofa	54.95	2.00e-149	522.00
IUUC-Tgu-117461	Taeniopygia guttata	57.57	0.00e+00	776.00
IUUC-Tru-117865	Takifugu rubripes	71.20	0.00e+00	1016.00
IUUC-Tsy-119036	Tarsius syrichta	66.93	2.00e-46	180.00
IUUC-Tni-120903	Tetraodon nigroviridis	67.60	0.00e+00	927.00
IUUC-Tca-121185	Theobroma cacao	50.50	4.00e-96	346.00
IUUC-Tae-125307	Triticum aestivum	50.66	3.00e-96	346.00
IUUC-Tur-126181	Triticum urartu	44.74	8.00e-85	308.00
IUUC-Tbe-127518	Tupaia belangeri	62.00	3.00e-69	256.00
IUUC-Ttr-128172	Tursiops truncatus	57.56	0.00e+00	719.00
IUUC-Vvi-131489	Vitis vinifera	51.50	1.00e-98	354.00
IUUC-Xtr-132915	Xenopus tropicalis	57.61	0.00e+00	768.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence