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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046458
Ensembl Protein ID ENSP00000387462.1
UniProt Accession Q96DT7; A4FVD0; Q86W96; Q8IXI9; Q96MH9; ZBT10_HUMAN
Genbank Protein ID CAC40989.1; CAD45447.1; BAB71309.1; AAH50061.1; AAI27099.1
Protein Name Zinc finger and BTB domain-containing protein 10; Zinc finger protein RIN ZF
Genbank Nucleotide ID AJ319673; AJ507398; AK056913; AC009812; BC127098
Gene Name ZBTB10; RINZF; RINZFC
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000205189.11 ENST00000379091.8 ENSP00000368384.4
ENSG00000205189.11 ENST00000430430.5 ENSP00000387462.1
ENSG00000205189.11 ENST00000426744.5 ENSP00000416134.2
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircRNADbCircNet
miRTarBasemicroRNATRANSFACTargetScan
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtBioGRID
mUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 8.90e-10 40.5 364 431
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalf.lmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv +vv g+ f+ahk +L a S++F+ l   ++ e+ +++++++++    + f+++l+FlY+g l +
   Q: 364  CDVSIVVSGKIFKAHKNILVAGSRFFKTLYcFSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVL 431
           8****************************95333333333666666668999************9976 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MSFSEMNRRT LAFRGGGLVT ASGGGSTNNN AGGEASAWPP QPQPRQPPPP APPALQPPNG 60
RGADEEVELE GLEPQDLEAS AGPAAGAAEE AKELLLPQDA GGPTSLGGGA GGPLLAERNR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046458|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAATGACTA CTGTCCGGGG CCCGAGGTGC TGCCTCGCAC AATGCATCAA AGGAGGTTGT 60
GTCCGTGGTC GTAACCTCTT CGCGTGAAAG GCACCGCCTG GTCCAGTCTT TGTGAAGGAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046458|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0488--Methylation
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000210--BTB/POZ_dom
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00651--BTB
SMART

SM00225--BTB
SM00355--ZnF_C2H2
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
KEGG hsa:65986
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002417 Ailuropoda melanoleuca 94.29 0.00e+00 1174.00
IUUC-Aca-004469 Anolis carolinensis 74.56 1.00e-125 442.00
IUUC-Ame-011346 Astyanax mexicanus 44.56 4.00e-111 395.00
IUUC-Bta-012861 Bos taurus 92.52 0.00e+00 1291.00
IUUC-Bci-013642 Botrytis cinerea 26.72 4.00e-06 45.40
IUUC-Cja-018896 Callithrix jacchus 96.85 0.00e+00 1250.00
IUUC-Cfa-020922 Canis familiaris 97.12 0.00e+00 1220.00
IUUC-Cpo-021973 Cavia porcellus 84.62 0.00e+00 1077.00
IUUC-Csa-023345 Chlorocebus sabaeus 97.37 0.00e+00 1412.00
IUUC-Dre-027561 Danio rerio 51.23 7.00e-108 384.00
IUUC-Dno-029805 Dasypus novemcinctus 91.41 0.00e+00 1212.00
IUUC-Dor-030754 Dipodomys ordii 83.09 0.00e+00 1150.00
IUUC-Ete-032796 Echinops telfairi 78.21 0.00e+00 1050.00
IUUC-Eca-033295 Equus caballus 94.91 0.00e+00 1038.00
IUUC-Eeu-034476 Erinaceus europaeus 85.79 0.00e+00 893.00
IUUC-Fca-036066 Felis catus 96.03 0.00e+00 1324.00
IUUC-Fal-036670 Ficedula albicollis 74.96 0.00e+00 914.00
IUUC-Gmo-039562 Gadus morhua 49.70 1.00e-119 423.00
IUUC-Gga-041244 Gallus gallus 74.26 9.00e-176 610.00
IUUC-Gac-041659 Gasterosteus aculeatus 51.53 3.00e-128 452.00
IUUC-Ggo-044525 Gorilla gorilla 97.01 0.00e+00 1351.00
IUUC-Itr-048557 Ictidomys tridecemlineatus 96.04 0.00e+00 863.00
IUUC-Loc-051835 Lepisosteus oculatus 40.83 3.00e-106 379.00
IUUC-Laf-053719 Loxodonta africana 86.97 0.00e+00 1233.00
IUUC-Mcc-055157 Macaca mulatta 97.14 0.00e+00 1409.00
IUUC-Meu-056336 Macropus eugenii 81.89 3.00e-151 529.00
IUUC-Mga-059399 Meleagris gallopavo 80.69 0.00e+00 832.00
IUUC-Mmr-061276 Microcebus murinus 93.01 0.00e+00 1345.00
IUUC-Mdo-062695 Monodelphis domestica 83.29 0.00e+00 1121.00
IUUC-Mmu-064205 Mus musculus 86.21 0.00e+00 1238.00
IUUC-Mpu-066671 Mustela putorius furo 94.97 0.00e+00 1347.00
IUUC-Mlu-067854 Myotis lucifugus 90.37 0.00e+00 1121.00
IUUC-Nle-069963 Nomascus leucogenys 98.50 0.00e+00 1391.00
IUUC-Ont-071653 Oreochromis niloticus 51.10 1.00e-160 560.00
IUUC-Oan-073626 Ornithorhynchus anatinus 73.52 4.00e-142 498.00
IUUC-Ocu-073862 Oryctolagus cuniculus 92.34 0.00e+00 1316.00
IUUC-Oga-088074 Otolemur garnettii 94.62 0.00e+00 1364.00
IUUC-Oar-089340 Ovis aries 89.45 0.00e+00 1339.00
IUUC-Ptr-090468 Pan troglodytes 99.77 0.00e+00 1414.00
IUUC-Psi-093295 Pelodiscus sinensis 76.95 0.00e+00 919.00
IUUC-Pfo-096654 Poecilia formosa 46.92 5.00e-150 525.00
IUUC-Pab-098683 Pongo abelii 95.53 0.00e+00 1330.00
IUUC-Pca-100679 Procavia capensis 88.60 0.00e+00 1224.00
IUUC-Pva-103039 Pteropus vampyrus 81.90 0.00e+00 822.00
IUUC-Rno-105993 Rattus norvegicus 85.61 0.00e+00 1122.00
IUUC-Sha-107020 Sarcophilus harrisii 83.72 0.00e+00 1111.00
IUUC-Ssl-108403 Sclerotinia sclerotiorum 30.61 9.00e-06 44.30
IUUC-Sar-113658 Sorex araneus 74.91 0.00e+00 788.00
IUUC-Ssc-115948 Sus scrofa 91.32 0.00e+00 1326.00
IUUC-Tgu-116753 Taeniopygia guttata 76.40 0.00e+00 927.00
IUUC-Tru-118354 Takifugu rubripes 61.11 4.00e-91 327.00
IUUC-Tsy-119124 Tarsius syrichta 88.75 0.00e+00 964.00
IUUC-Tni-119956 Tetraodon nigroviridis 47.16 9.00e-96 344.00
IUUC-Tbe-127314 Tupaia belangeri 86.20 0.00e+00 931.00
IUUC-Ttr-128408 Tursiops truncatus 91.77 0.00e+00 963.00
IUUC-Xtr-132456 Xenopus tropicalis 62.71 0.00e+00 766.00
Created Date 25-Jun-2017

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