iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052327

Ensembl Protein ID

ENSLOCP00000009443.1

UniProt Accession

W5MM34; W5MM34_LEPOC

Genbank Protein ID

ENSLOCP00000009443

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01034733

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000007772.1	ENSLOCT00000009454.1	ENSLOCP00000009443.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.20e-41	136.4	225	259
UBD/Beta-Prp	1.20e-51	175.8	106	341

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH++++++++f ++ + +++GsdD t+k++Dlr +
   Q: 225  GHESDINAICFfPNgNAICTGSDDATCKLFDLRAD 259
           8*********99777*****************987 PP

UBD/Beta-Prp

   S: 18   fspdksllatgsrdgtikvwdvttgkl....lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           ++p+++++a g+ d++  +++++t        r+l  h++  ++++f +d   +vt+s D t  +wd++tg++  +++gh+ + +sl++
   Q: 106  YAPSGNFVACGGLDNMCSIYNLKTREGnvkvSRELAAHTGYLSCCRFLNDN-EIVTSSGDTTCALWDIETGTQKTIFTGHTGDCMSLAV 193
           789******************9997656687999****************7.7************************************ PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsvyslsfd 189
           sp+ + ++sG  d+ +++wd+++g+c + t++gh++ +n +++ p+gn + +Gs+D t++l+dl+ ++ l  +  +      ++s++++
   Q: 194  SPDFNLFISGACDSSAKLWDVREGTCRQ-TFTGHESDINAICFFPNGNAICTGSDDATCKLFDLRADQELIGFshE-SIICGITSIAMS 280
           ****************************.********************************************533.3567899999** PP
   S: 190  sngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWd 250
           ++g+ +++g +d   ++wd  + e v  l gh++ v+++ +++++    +gs D  ++iW+
   Q: 281  RSGRLILAGYDDFNCNIWDTLKAERVGVLSGHDNRVSCIGVTSDGMAACTGSWDSFLKIWN 341
           ************************************************************8 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

AMGEVEQLRK EAEALKQQIA DARKAVADTT LAEMVAGTEV VGRIQMRTRK TLRGHLAKIY 60
AMHWATDSRL LVSASQDGKL IVWDSYTTNK VNAIPLKSSW VMTCAYAPSG NFVACGGLDN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAAATCGCC GAGGGTCACA AGATCGGAGC TGAAAGACAA ACAGAGCAGC AGACTGACAG 60
CACAGGACGG CGACGCTGCA CAGAGAGAGC TCAGCGATCA ACCGCGTGCC TCCCAGTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002370	Ailuropoda melanoleuca	86.18	0.00e+00	633.00
IUUC-Apl-004079	Anas platyrhynchos	88.53	0.00e+00	645.00
IUUC-Aca-004539	Anolis carolinensis	84.71	2.00e-179	621.00
IUUC-Bta-012810	Bos taurus	86.76	0.00e+00	635.00
IUUC-Cja-019894	Callithrix jacchus	87.35	0.00e+00	640.00
IUUC-Cfa-020140	Canis familiaris	86.47	0.00e+00	632.00
IUUC-Cpo-021908	Cavia porcellus	86.76	0.00e+00	635.00
IUUC-Csa-023321	Chlorocebus sabaeus	88.24	0.00e+00	642.00
IUUC-Dno-029783	Dasypus novemcinctus	85.85	3.00e-168	583.00
IUUC-Ete-032435	Echinops telfairi	79.41	9.00e-164	568.00
IUUC-Eca-034169	Equus caballus	86.76	0.00e+00	634.00
IUUC-Eeu-034631	Erinaceus europaeus	81.17	3.00e-152	530.00
IUUC-Fca-035392	Felis catus	87.06	0.00e+00	637.00
IUUC-Fal-036902	Ficedula albicollis	85.88	0.00e+00	633.00
IUUC-Gga-040655	Gallus gallus	87.39	0.00e+00	633.00
IUUC-Ggo-045346	Gorilla gorilla	88.24	0.00e+00	642.00
IUUC-Hsa-046203	Homo sapiens	88.24	0.00e+00	642.00
IUUC-Itr-048501	Ictidomys tridecemlineatus	86.47	0.00e+00	634.00
IUUC-Laf-053616	Loxodonta africana	85.88	0.00e+00	632.00
IUUC-Mcc-055798	Macaca mulatta	88.24	0.00e+00	642.00
IUUC-Mga-059516	Meleagris gallopavo	88.24	0.00e+00	644.00
IUUC-Mmr-061701	Microcebus murinus	86.47	0.00e+00	635.00
IUUC-Mdo-061879	Monodelphis domestica	86.76	0.00e+00	634.00
IUUC-Mmu-063132	Mus musculus	86.76	0.00e+00	634.00
IUUC-Mpu-066365	Mustela putorius furo	86.22	0.00e+00	634.00
IUUC-Mlu-067628	Myotis lucifugus	86.18	0.00e+00	630.00
IUUC-Nle-069015	Nomascus leucogenys	86.76	0.00e+00	627.00
IUUC-Opr-070261	Ochotona princeps	86.76	0.00e+00	635.00
IUUC-Ocu-074255	Oryctolagus cuniculus	86.76	0.00e+00	635.00
IUUC-Oga-088685	Otolemur garnettii	86.76	0.00e+00	635.00
IUUC-Oar-089373	Ovis aries	84.75	2.00e-174	604.00
IUUC-Ptr-090627	Pan troglodytes	85.59	7.00e-180	622.00
IUUC-Pan-092347	Papio anubis	88.24	0.00e+00	642.00
IUUC-Psi-092965	Pelodiscus sinensis	88.53	0.00e+00	645.00
IUUC-Pab-098335	Pongo abelii	88.24	0.00e+00	642.00
IUUC-Pva-102666	Pteropus vampyrus	86.76	0.00e+00	636.00
IUUC-Rno-105834	Rattus norvegicus	86.76	8.00e-175	605.00
IUUC-Sha-107128	Sarcophilus harrisii	87.94	0.00e+00	639.00
IUUC-Ssc-115886	Sus scrofa	87.06	0.00e+00	635.00
IUUC-Tgu-116461	Taeniopygia guttata	86.18	0.00e+00	634.00
IUUC-Tni-120492	Tetraodon nigroviridis	82.99	3.00e-172	597.00
IUUC-Tbe-127694	Tupaia belangeri	73.82	1.00e-139	489.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence