iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049812

Ensembl Protein ID

ENSLACP00000003859.1

UniProt Accession

H3A2I8; H3A2I8_LATCH

Genbank Protein ID

ENSLACP00000003859

Protein Name

Phosphoinositide phospholipase C

Genbank Nucleotide ID

AFYH01210003

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000003436.1	ENSLACT00000003894.1	ENSLACP00000003859.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.30e-12	45.0	675	730

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekle 63
           +v++lydy+aq +deL++ k  +v+ +  ++qd+gW++g  +  gk+ l fP+n+ve++ 
   Q: 675  TVKALYDYKAQREDELSFCKQAIVHNV--DKQDGGWWRG--DYGGKKQLwFPANYVEEIT 730
           79************************9..9*********..676666655*******985 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

AFGEEDVNLW INGLNWLVTD TQKSPTPIQI ERWLRKQFDS MDRAKDGSIT VKDLKAMLPQ 60
VNYRVPNMRF LRDKLLEVEA RVDMSFGHFV QFYKNLMFDA QRSNEIFNLK ASLNRNVDRP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNACACA CACACACACA CACACACACA CTATTTTTAT 60
ATATATATAT ATATATACAC ATATATGCAG TCTACCTGCC GATGTACCAG CTCCCTGATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer

Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR002048--EF_hand_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50222--EF_HAND_2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3

Pfam

PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005509--F:calcium ion binding
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0035556--P:intracellular signal transduction
GO:0009395--P:phospholipid catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003541	Anas platyrhynchos	84.46	0.00e+00	1944.00
IUUC-Fal-037454	Ficedula albicollis	85.12	0.00e+00	1996.00
IUUC-Gga-040211	Gallus gallus	85.25	0.00e+00	1961.00
IUUC-Mga-059588	Meleagris gallopavo	85.28	0.00e+00	1969.00
IUUC-Tgu-116979	Taeniopygia guttata	77.86	0.00e+00	1497.00
IUUC-Tni-120833	Tetraodon nigroviridis	74.74	0.00e+00	1762.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence