iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000020895.3	ENSMMUT00000042102.2	ENSMMUP00000035100.2
ENSMMUG00000020895.3	ENSMMUT00000029382.3	ENSMMUP00000027491.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.70e-14	53.1	726	777

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek...wiCpkCrs 53
           +C +C++++++   l+ C+ C+  +H +Cl ++  + +p+++k   w C++C++
   Q: 726  SCGICKKNHDQH-LLLLCDTCKLHYHLGCLDPP-LTRMPRKTKnsyWQCSECDQ 777
           6*******9976.8*******************.555555544568******87 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MDRSSKRRQV KPLAASLLEA LDYDSSDDSD FKVGDASDSE GSGNGSEDAS KDSGEGSCSD 60
SEENILEEEL NEDIKVKEEQ LKNSAEEVLS AEKQLIKMEK KEEEENGERP RKKKEKEKEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTAAGTGTG TCCAAGGCCT CTGCGGCGAG GGATCCATTT CAGCCATTCT AGATGTCAGG 60
GCCGGTGGGA GCAGGGCAGG GGTGGGAGAA CCCTGCGGGA AAGCTGGATT GGTGGACCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD

SMART

SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0048286--P:lung alveolus development
GO:2000791--P:negative regulation of mesenchymal cell proliferation involved in lung development
GO:2000584--P:negative regulation of platelet-derived growth factor receptor-alpha signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001978	Ailuropoda melanoleuca	95.84	0.00e+00	1478.00
IUUC-Apl-003491	Anas platyrhynchos	93.16	0.00e+00	1323.00
IUUC-Aca-004470	Anolis carolinensis	89.69	0.00e+00	1295.00
IUUC-Ame-011188	Astyanax mexicanus	80.94	0.00e+00	1046.00
IUUC-Bta-012312	Bos taurus	95.92	0.00e+00	1392.00
IUUC-Cel-018258	Caenorhabditis elegans	28.32	9.00e-48	184.00
IUUC-Cja-019931	Callithrix jacchus	97.49	0.00e+00	1513.00
IUUC-Cfa-021102	Canis familiaris	97.44	0.00e+00	1463.00
IUUC-Csa-023396	Chlorocebus sabaeus	99.75	0.00e+00	1489.00
IUUC-Cin-025300	Ciona intestinalis	34.85	6.00e-75	275.00
IUUC-Csv-026365	Ciona savignyi	59.65	4.00e-16	75.90
IUUC-Dre-028450	Danio rerio	81.16	0.00e+00	1037.00
IUUC-Dno-029245	Dasypus novemcinctus	96.15	0.00e+00	1393.00
IUUC-Dme-031650	Drosophila melanogaster	38.88	2.00e-118	420.00
IUUC-Ete-032829	Echinops telfairi	82.53	0.00e+00	1190.00
IUUC-Eca-033527	Equus caballus	97.09	0.00e+00	1463.00
IUUC-Eeu-035092	Erinaceus europaeus	83.58	0.00e+00	1043.00
IUUC-Fal-037349	Ficedula albicollis	92.44	0.00e+00	1326.00
IUUC-Gmo-038924	Gadus morhua	79.69	0.00e+00	1019.00
IUUC-Gga-040604	Gallus gallus	92.46	0.00e+00	1352.00
IUUC-Gac-041895	Gasterosteus aculeatus	78.51	0.00e+00	1014.00
IUUC-Ggo-044724	Gorilla gorilla	92.09	0.00e+00	1330.00
IUUC-Hsa-046740	Homo sapiens	98.60	0.00e+00	1467.00
IUUC-Lch-050481	Latimeria chalumnae	90.85	0.00e+00	1238.00
IUUC-Loc-052530	Lepisosteus oculatus	83.60	0.00e+00	1251.00
IUUC-Laf-053683	Loxodonta africana	95.85	0.00e+00	1437.00
IUUC-Meu-056124	Macropus eugenii	71.57	0.00e+00	942.00
IUUC-Mmr-061716	Microcebus murinus	98.22	0.00e+00	1471.00
IUUC-Mmu-064063	Mus musculus	96.69	0.00e+00	1411.00
IUUC-Mpu-065850	Mustela putorius furo	97.54	0.00e+00	1425.00
IUUC-Mlu-067977	Myotis lucifugus	98.44	0.00e+00	1333.00
IUUC-Nle-070024	Nomascus leucogenys	97.64	0.00e+00	1468.00
IUUC-Opr-070669	Ochotona princeps	92.03	0.00e+00	1008.00
IUUC-Ont-072407	Oreochromis niloticus	72.52	0.00e+00	1141.00
IUUC-Oga-088503	Otolemur garnettii	94.60	0.00e+00	1355.00
IUUC-Oar-090254	Ovis aries	96.03	0.00e+00	1511.00
IUUC-Ptr-090811	Pan troglodytes	100.00	0.00e+00	1342.00
IUUC-Psi-093869	Pelodiscus sinensis	93.18	0.00e+00	1363.00
IUUC-Pma-094703	Petromyzon marinus	60.42	0.00e+00	751.00
IUUC-Pfo-097375	Poecilia formosa	83.77	0.00e+00	1021.00
IUUC-Pab-098645	Pongo abelii	98.60	0.00e+00	1466.00
IUUC-Pca-100931	Procavia capensis	86.51	0.00e+00	941.00
IUUC-Pva-102902	Pteropus vampyrus	92.87	0.00e+00	1424.00
IUUC-Rno-105725	Rattus norvegicus	98.42	0.00e+00	1389.00
IUUC-Sha-107008	Sarcophilus harrisii	91.26	0.00e+00	1358.00
IUUC-Sar-113710	Sorex araneus	89.09	0.00e+00	1025.00
IUUC-Ssc-116271	Sus scrofa	97.41	0.00e+00	1406.00
IUUC-Tru-117706	Takifugu rubripes	80.91	0.00e+00	1077.00
IUUC-Tsy-118886	Tarsius syrichta	93.28	0.00e+00	1469.00
IUUC-Tni-120623	Tetraodon nigroviridis	81.01	0.00e+00	998.00
IUUC-Tbe-127618	Tupaia belangeri	83.22	2.00e-132	466.00
IUUC-Ttr-129058	Tursiops truncatus	93.12	0.00e+00	1367.00
IUUC-Vpa-130327	Vicugna pacos	96.56	0.00e+00	1456.00
IUUC-Xtr-132030	Xenopus tropicalis	76.71	0.00e+00	1235.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence