iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049824

Ensembl Protein ID

ENSLACP00000009795.1

UniProt Accession

H3AJH4; H3AJH4_LATCH

Genbank Protein ID

ENSLACP00000009795

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01170571

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000008638.1	ENSLACT00000009871.1	ENSLACP00000009795.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.90e-81	272.7	391	682

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           k+dlkk+l+v+fvgE+gld+gG+t+e++ ll++e+++pd+g+f+y+++++++++ + +      ++ + ++++G l+g+a++++  ld+
   Q: 391  KADLKKKLKVTFVGEAGLDMGGLTKEWFLLLVREIFHPDYGMFTYHKDSHSHWFSSFKC-----DNYSEYHLIGALMGLAVYNSITLDI 474
           789**************************************************977766.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +l+l+dl +v+pel++ l e++++ e ++ee  l  tf+v +e++g +k ++LkpgG++ipV
   Q: 475  QFPPCCYKKLLSPpivpcdqttpigisNLTLDDLFQVMPELAHGLSELLSY-EGNVEED-LYTTFQVFQEEFGVIKFYNLKPGGDKIPV 561
           **********999777776677666666**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn N++eYv+l++++ l++ i +q++af+ Gf++v+  + l l+++ee+e+l+cG++++dv +l++ t+y+g y +++p+i++Fw+v+ 
   Q: 562  TNRNRKEYVQLYIDFLLNKAIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGRPDLDVCALQRATQYDG-YIKNDPTIRYFWDVVV 649
           **********************************************************************76.**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvir 290
           +f  + +k++L+F+Tgs+r+P+gG+a+l+   f i 
   Q: 650  GFPLDLQKKLLHFATGSDRVPVGGMADLN---FKIC 682
           *****************************...3333 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

GIDNGTKSQF STFSGVISTI NQKKEAAGRG SPTQQVIPNS KNVRELPPIC PDVRRKQRIS 60
IDTLPPEMKA PVPPEPVIPM RTKTVKEFQE DMEKAKTSGD WRVVSDFFLT TFDSFLELNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTATAGATA ATGGAACCAA AAGCCAATTT TCCACTTTCA GTGGTGTCAT CTCTACAATC 60
AACCAGAAGA AAGAAGCAGC TGGCAGAGGT TCACCAACAC AGCAGGTTAT ACCCAACAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	82.01	0.00e+00	1179.00
IUUC-Apl-003589	Anas platyrhynchos	81.50	0.00e+00	1173.00
IUUC-Aca-004350	Anolis carolinensis	76.99	0.00e+00	1076.00
IUUC-Acl-008288	Aspergillus clavatus	35.61	2.00e-86	313.00
IUUC-Afl-008402	Aspergillus flavus	33.93	9.00e-79	288.00
IUUC-Afu-008762	Aspergillus fumigatus	34.68	6.00e-83	302.00
IUUC-Ang-009791	Aspergillus niger	34.21	3.00e-79	290.00
IUUC-Aor-009921	Aspergillus oryzae	33.75	3.00e-78	286.00
IUUC-Ate-010295	Aspergillus terreus	35.06	6.00e-86	312.00
IUUC-Ame-010660	Astyanax mexicanus	80.77	6.00e-130	456.00
IUUC-Bta-012945	Bos taurus	81.77	0.00e+00	1148.00
IUUC-Bci-013697	Botrytis cinerea	37.29	6.00e-71	262.00
IUUC-Cja-019263	Callithrix jacchus	79.28	0.00e+00	1115.00
IUUC-Cfa-020486	Canis familiaris	84.32	0.00e+00	1070.00
IUUC-Cpo-021755	Cavia porcellus	81.04	0.00e+00	1147.00
IUUC-Csa-023814	Chlorocebus sabaeus	80.32	0.00e+00	1132.00
IUUC-Cho-024980	Choloepus hoffmanni	65.56	0.00e+00	872.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	43.00	5.00e-84	306.00
IUUC-Dre-028551	Danio rerio	76.67	0.00e+00	1066.00
IUUC-Dno-029497	Dasypus novemcinctus	80.03	0.00e+00	1035.00
IUUC-Dor-030867	Dipodomys ordii	69.81	0.00e+00	941.00
IUUC-Dse-031239	Dothistroma septosporum	32.29	2.00e-78	288.00
IUUC-Ete-032902	Echinops telfairi	66.86	0.00e+00	919.00
IUUC-Eca-033678	Equus caballus	81.33	0.00e+00	1150.00
IUUC-Eeu-035262	Erinaceus europaeus	67.54	0.00e+00	854.00
IUUC-Fca-035590	Felis catus	81.91	0.00e+00	1178.00
IUUC-Fal-037123	Ficedula albicollis	78.30	0.00e+00	1110.00
IUUC-Gmo-039553	Gadus morhua	67.61	0.00e+00	794.00
IUUC-Ggr-040110	Gaeumannomyces graminis	40.78	8.00e-88	318.00
IUUC-Gga-040406	Gallus gallus	83.07	0.00e+00	1196.00
IUUC-Gac-042141	Gasterosteus aculeatus	77.57	0.00e+00	1039.00
IUUC-Ggo-045504	Gorilla gorilla	79.83	0.00e+00	1124.00
IUUC-Hsa-045786	Homo sapiens	80.43	0.00e+00	1129.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	77.08	0.00e+00	1020.00
IUUC-Loc-052173	Lepisosteus oculatus	80.92	0.00e+00	1108.00
IUUC-Laf-054017	Loxodonta africana	82.87	0.00e+00	1105.00
IUUC-Mcc-055713	Macaca mulatta	80.00	0.00e+00	1108.00
IUUC-Meu-056212	Macropus eugenii	67.40	5.00e-101	361.00
IUUC-Mla-059187	Melampsora laricipopulina	41.88	4.00e-68	251.00
IUUC-Mga-059884	Meleagris gallopavo	75.32	0.00e+00	1037.00
IUUC-Mmr-061344	Microcebus murinus	80.14	0.00e+00	1136.00
IUUC-Mdo-062653	Monodelphis domestica	79.89	0.00e+00	1120.00
IUUC-Mmu-063775	Mus musculus	79.05	0.00e+00	1050.00
IUUC-Mpu-066069	Mustela putorius furo	83.63	0.00e+00	1087.00
IUUC-Mlu-067925	Myotis lucifugus	81.04	0.00e+00	1131.00
IUUC-Nfi-068439	Neosartorya fischeri	33.98	1.00e-82	301.00
IUUC-Ncr-068903	Neurospora crassa	38.72	5.00e-83	303.00
IUUC-Nle-070046	Nomascus leucogenys	80.12	0.00e+00	1133.00
IUUC-Opr-071085	Ochotona princeps	82.86	9.00e-106	377.00
IUUC-Ont-072126	Oreochromis niloticus	75.40	0.00e+00	1082.00
IUUC-Oan-072933	Ornithorhynchus anatinus	83.09	0.00e+00	1029.00
IUUC-Ocu-073800	Oryctolagus cuniculus	82.99	0.00e+00	1069.00
IUUC-Ola-086988	Oryzias latipes	77.62	0.00e+00	1041.00
IUUC-Oga-088117	Otolemur garnettii	83.18	0.00e+00	919.00
IUUC-Oar-089371	Ovis aries	81.48	0.00e+00	1127.00
IUUC-Ptr-090551	Pan troglodytes	79.56	0.00e+00	1099.00
IUUC-Pan-092067	Papio anubis	80.46	0.00e+00	1114.00
IUUC-Psi-092963	Pelodiscus sinensis	82.49	0.00e+00	1115.00
IUUC-Pfo-096562	Poecilia formosa	76.58	0.00e+00	1036.00
IUUC-Pab-098680	Pongo abelii	80.43	0.00e+00	1127.00
IUUC-Pca-100986	Procavia capensis	66.50	0.00e+00	803.00
IUUC-Pva-102219	Pteropus vampyrus	68.55	0.00e+00	907.00
IUUC-Pgr-103315	Puccinia graminis	35.69	9.00e-79	288.00
IUUC-Ptt-103736	Puccinia triticina	40.84	4.00e-78	286.00
IUUC-Rno-105270	Rattus norvegicus	78.87	0.00e+00	1055.00
IUUC-Sha-106819	Sarcophilus harrisii	81.04	0.00e+00	1170.00
IUUC-Sar-113134	Sorex araneus	72.79	0.00e+00	984.00
IUUC-Ssc-115441	Sus scrofa	81.77	0.00e+00	1135.00
IUUC-Tgu-117166	Taeniopygia guttata	80.61	0.00e+00	1127.00
IUUC-Tsy-118898	Tarsius syrichta	71.28	0.00e+00	927.00
IUUC-Tvi-122644	Trichoderma virens	37.69	4.00e-82	299.00
IUUC-Tme-127004	Tuber melanosporum	35.58	3.00e-87	317.00
IUUC-Tbe-127292	Tupaia belangeri	65.56	0.00e+00	833.00
IUUC-Ttr-128352	Tursiops truncatus	78.15	0.00e+00	1086.00
IUUC-Vpa-130218	Vicugna pacos	79.04	0.00e+00	854.00
IUUC-Xtr-132594	Xenopus tropicalis	80.72	0.00e+00	1054.00
IUUC-Xma-134157	Xiphophorus maculatus	77.01	0.00e+00	1038.00
IUUC-Yli-134470	Yarrowia lipolytica	35.71	1.00e-62	235.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence