iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000060544.1	ENSRNOT00000087025.1	ENSRNOP00000072712.1
ENSRNOG00000060544.1	ENSRNOT00000077928.1	ENSRNOP00000073808.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.60e-23	81.5	313	359

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 313  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLLPP-LHDVPKGD-WRCPKCL 359
           8********988.6*******************.*******7.******5 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MEPATALPPG PRPALPLGGP GPLGEFLPPP ECPVFEPSWE EFADPFAFIH KIRPIAEQTG 60
ICKVRPPPDW QPPFACDVDK LHFTPRIQRL NELEAQTRVK LNFLDQIAKY WELQGSTLKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAGCGGCAA GACGTCGTCG GAGGAAGGCT GAAAAAGCCC TAGGTGTTGC CGTTGCTAGT 60
AGAAGTCGGA CTTGTCGCCC GAGCTGTGCG TGTGCACAGG TTTCGGACGG AGCGGAGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0044344--P:cellular response to fibroblast growth factor stimulus
GO:0070306--P:lens fiber cell differentiation
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0060992--P:response to fungicide
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	32.04	6.00e-100	359.00
IUUC-Aml-001963	Ailuropoda melanoleuca	92.09	0.00e+00	2638.00
IUUC-Apl-003770	Anas platyrhynchos	84.60	0.00e+00	2085.00
IUUC-Aca-004867	Anolis carolinensis	80.24	0.00e+00	2440.00
IUUC-Ath-007218	Arabidopsis thaliana	35.56	3.00e-09	58.50
IUUC-Acl-008162	Aspergillus clavatus	31.36	5.00e-113	403.00
IUUC-Afu-008796	Aspergillus fumigatus	30.52	1.00e-113	405.00
IUUC-Ame-010620	Astyanax mexicanus	62.85	0.00e+00	1897.00
IUUC-Bta-012733	Bos taurus	88.43	0.00e+00	2566.00
IUUC-Bci-013992	Botrytis cinerea	29.85	4.00e-109	390.00
IUUC-Bdi-014050	Brachypodium distachyon	29.62	5.00e-122	433.00
IUUC-Bol-015336	Brassica oleracea	35.07	1.00e-14	77.00
IUUC-Cja-019050	Callithrix jacchus	92.73	0.00e+00	2757.00
IUUC-Cfa-021015	Canis familiaris	92.08	0.00e+00	2633.00
IUUC-Cpo-022340	Cavia porcellus	92.29	0.00e+00	2608.00
IUUC-Csa-023441	Chlorocebus sabaeus	93.08	0.00e+00	2727.00
IUUC-Cho-024823	Choloepus hoffmanni	97.01	0.00e+00	1687.00
IUUC-Cgl-026613	Colletotrichum gloeosporioides	28.77	1.00e-104	375.00
IUUC-Cne-026851	Cryptococcus neoformans	28.47	1.00e-109	392.00
IUUC-Dre-027707	Danio rerio	60.99	0.00e+00	1821.00
IUUC-Dno-028978	Dasypus novemcinctus	92.47	0.00e+00	2706.00
IUUC-Dor-030854	Dipodomys ordii	88.79	0.00e+00	1203.00
IUUC-Ete-032760	Echinops telfairi	86.84	0.00e+00	1736.00
IUUC-Eca-034370	Equus caballus	92.35	0.00e+00	2578.00
IUUC-Eeu-035012	Erinaceus europaeus	73.38	0.00e+00	1787.00
IUUC-Fca-035494	Felis catus	92.70	0.00e+00	2653.00
IUUC-Fal-037631	Ficedula albicollis	80.77	0.00e+00	2333.00
IUUC-Gmo-039522	Gadus morhua	59.22	0.00e+00	1721.00
IUUC-Gga-040802	Gallus gallus	81.43	0.00e+00	2375.00
IUUC-Gac-041563	Gasterosteus aculeatus	61.53	0.00e+00	1835.00
IUUC-Gma-042675	Glycine max	32.60	2.00e-100	361.00
IUUC-Ggo-044856	Gorilla gorilla	75.80	0.00e+00	2065.00
IUUC-Hsa-045888	Homo sapiens	91.11	0.00e+00	2744.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	1.00e-15	79.00
IUUC-Itr-048297	Ictidomys tridecemlineatus	93.34	0.00e+00	2724.00
IUUC-Lch-050483	Latimeria chalumnae	65.90	0.00e+00	1976.00
IUUC-Lpe-051537	Leersia perrieri	31.47	1.00e-90	328.00
IUUC-Loc-052550	Lepisosteus oculatus	70.33	0.00e+00	2080.00
IUUC-Laf-053761	Loxodonta africana	90.73	0.00e+00	2578.00
IUUC-Mcc-055505	Macaca mulatta	91.09	0.00e+00	2738.00
IUUC-Mga-059358	Meleagris gallopavo	80.55	0.00e+00	2351.00
IUUC-Mmr-060863	Microcebus murinus	92.89	0.00e+00	2716.00
IUUC-Mdo-061957	Monodelphis domestica	86.55	0.00e+00	2585.00
IUUC-Mmu-063944	Mus musculus	96.37	0.00e+00	2845.00
IUUC-Mac-065069	Musa acuminata	36.04	2.00e-08	55.80
IUUC-Mpu-066719	Mustela putorius furo	90.39	0.00e+00	2686.00
IUUC-Mlu-068086	Myotis lucifugus	85.88	0.00e+00	2472.00
IUUC-Nle-069256	Nomascus leucogenys	90.06	0.00e+00	2697.00
IUUC-Ont-071756	Oreochromis niloticus	61.74	0.00e+00	1859.00
IUUC-Oan-073568	Ornithorhynchus anatinus	86.76	0.00e+00	2594.00
IUUC-Ocu-073961	Oryctolagus cuniculus	89.95	0.00e+00	2645.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	1.00e-16	82.40
IUUC-Olo-080668	Oryza longistaminata	38.83	3.00e-16	82.00
IUUC-Opu-083164	Oryza punctata	30.92	4.00e-88	320.00
IUUC-Oru-084630	Oryza rufipogon	26.93	7.00e-83	303.00
IUUC-Osa-085487	Oryza sativa	38.83	1.00e-16	82.40
IUUC-Ola-086448	Oryzias latipes	61.42	0.00e+00	1851.00
IUUC-Oga-088501	Otolemur garnettii	88.10	0.00e+00	2257.00
IUUC-Oar-090162	Ovis aries	88.02	0.00e+00	2555.00
IUUC-Ptr-090816	Pan troglodytes	91.17	0.00e+00	2751.00
IUUC-Pan-092764	Papio anubis	93.14	0.00e+00	2729.00
IUUC-Psi-093918	Pelodiscus sinensis	80.04	0.00e+00	2137.00
IUUC-Ppa-095839	Physcomitrella patens	38.60	1.00e-15	80.10
IUUC-Pfo-096672	Poecilia formosa	61.53	0.00e+00	1809.00
IUUC-Pab-097854	Pongo abelii	88.45	0.00e+00	2097.00
IUUC-Pca-100241	Procavia capensis	87.00	0.00e+00	1691.00
IUUC-Pva-103035	Pteropus vampyrus	82.50	0.00e+00	2110.00
IUUC-Sce-106207	Saccharomyces cerevisiae	35.59	4.00e-74	272.00
IUUC-Sly-111298	Solanum lycopersicum	42.66	1.00e-102	368.00
IUUC-Sar-113477	Sorex araneus	87.25	0.00e+00	2310.00
IUUC-Ssc-116132	Sus scrofa	91.37	0.00e+00	2311.00
IUUC-Tgu-117452	Taeniopygia guttata	81.35	0.00e+00	2336.00
IUUC-Tru-117561	Takifugu rubripes	59.78	0.00e+00	1775.00
IUUC-Tsy-119271	Tarsius syrichta	91.14	0.00e+00	2066.00
IUUC-Tni-119650	Tetraodon nigroviridis	61.24	0.00e+00	1806.00
IUUC-Tur-126632	Triticum urartu	31.72	3.00e-99	357.00
IUUC-Tbe-127890	Tupaia belangeri	86.25	0.00e+00	1443.00
IUUC-Ttr-128546	Tursiops truncatus	87.73	0.00e+00	1941.00
IUUC-Vpa-130432	Vicugna pacos	86.32	0.00e+00	1484.00
IUUC-Vvi-131071	Vitis vinifera	45.88	9.00e-83	302.00
IUUC-Xtr-132008	Xenopus tropicalis	70.14	0.00e+00	2079.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence