iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118078

UUCD1 version

UUC-TaR-00843

Ensembl Protein ID

ENSTRUP00000039290.1

UniProt Accession

H2UQR7; H2UQR7_TAKRU

Protein Name

Uncharacterized protein

Gene Name

klhl3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000015376.1	ENSTRUT00000039431.1	ENSTRUP00000039290.1
ENSTRUG00000015376.1	ENSTRUT00000039432.1	ENSTRUP00000039291.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.60e-20	73.8	49	115
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.60e-12	45.3	148	179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv+lv g +e++ah++vLa++S++F a+f+++++es+  + vei++v+ + +r l++++Yt +++ +
   Q: 49   CDVQLVAGSVEVPAHRVVLASCSPYFCAMFTGNMSEST-APQVEIREVDGQTLRKLVDYIYTAEIEVT 115
           8************************************9.************************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclgi++fAdl++c++L ++a+ f+++hF+
   Q: 148  PTNCLGIRAFADLHTCTQLLSQAHAFAEQHFT 179
           78*****************************7 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

VATPAMPHPN CSTDAEEDTV NGRMPTFNHT HMRKAFQLMN DLRSKQILCD VQLVAGSVEV 60
PAHRVVLASC SPYFCAMFTG NMSESTAPQV EIREVDGQTL RKLVDYIYTA EIEVTEDNVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGCCACAC CGGCCATGCC ACATCCGAAC TGTTCCACGG ATGCCGAGGA GGACACCGTG 60
AATGGAAGGA TGCCCACGTT CAACCATACG CACATGAGGA AGGCTTTCCA GCTGATGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0050801--P:ion homeostasis
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0070294--P:renal sodium ion absorption

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001632	Ailuropoda melanoleuca	78.18	0.00e+00	944.00
IUUC-Apl-003965	Anas platyrhynchos	78.78	0.00e+00	928.00
IUUC-Aca-004912	Anolis carolinensis	77.68	0.00e+00	922.00
IUUC-Ame-010670	Astyanax mexicanus	85.86	0.00e+00	990.00
IUUC-Bta-013354	Bos taurus	79.55	0.00e+00	947.00
IUUC-Bol-016582	Brassica oleracea	31.35	1.00e-12	68.90
IUUC-Bra-017771	Brassica rapa	30.43	1.00e-13	72.00
IUUC-Cel-018136	Caenorhabditis elegans	40.33	3.00e-126	445.00
IUUC-Cja-019183	Callithrix jacchus	76.88	0.00e+00	852.00
IUUC-Cfa-020465	Canis familiaris	78.70	0.00e+00	934.00
IUUC-Cpo-022115	Cavia porcellus	78.62	0.00e+00	950.00
IUUC-Csa-024219	Chlorocebus sabaeus	79.37	0.00e+00	949.00
IUUC-Csv-026032	Ciona savignyi	59.46	0.00e+00	678.00
IUUC-Dre-028524	Danio rerio	78.51	0.00e+00	985.00
IUUC-Dno-029075	Dasypus novemcinctus	80.64	0.00e+00	950.00
IUUC-Dor-030156	Dipodomys ordii	65.00	0.00e+00	764.00
IUUC-Ete-033064	Echinops telfairi	66.35	0.00e+00	676.00
IUUC-Eca-033887	Equus caballus	78.73	0.00e+00	939.00
IUUC-Fca-035375	Felis catus	78.35	0.00e+00	947.00
IUUC-Fal-037119	Ficedula albicollis	80.00	0.00e+00	913.00
IUUC-Gga-041094	Gallus gallus	79.02	0.00e+00	924.00
IUUC-Gac-042585	Gasterosteus aculeatus	89.29	0.00e+00	1061.00
IUUC-Ggo-045485	Gorilla gorilla	79.13	0.00e+00	941.00
IUUC-Hsa-046717	Homo sapiens	79.55	0.00e+00	951.00
IUUC-Itr-048605	Ictidomys tridecemlineatus	78.62	0.00e+00	951.00
IUUC-Lch-050246	Latimeria chalumnae	78.33	0.00e+00	904.00
IUUC-Laf-053700	Loxodonta africana	78.40	0.00e+00	936.00
IUUC-Mcc-054732	Macaca mulatta	81.19	0.00e+00	856.00
IUUC-Mga-059994	Meleagris gallopavo	78.61	0.00e+00	827.00
IUUC-Mdo-062923	Monodelphis domestica	78.28	0.00e+00	952.00
IUUC-Mmu-063842	Mus musculus	78.45	0.00e+00	948.00
IUUC-Mpu-066380	Mustela putorius furo	79.79	0.00e+00	950.00
IUUC-Mlu-067922	Myotis lucifugus	79.33	0.00e+00	934.00
IUUC-Nle-069761	Nomascus leucogenys	79.65	0.00e+00	949.00
IUUC-Opr-070287	Ochotona princeps	72.70	0.00e+00	836.00
IUUC-Ont-071654	Oreochromis niloticus	92.15	0.00e+00	1116.00
IUUC-Ocu-074957	Oryctolagus cuniculus	78.18	0.00e+00	937.00
IUUC-Ola-086853	Oryzias latipes	88.74	0.00e+00	1034.00
IUUC-Oga-088559	Otolemur garnettii	78.99	0.00e+00	944.00
IUUC-Oar-089925	Ovis aries	79.55	0.00e+00	947.00
IUUC-Ptr-091487	Pan troglodytes	79.55	0.00e+00	951.00
IUUC-Pan-091705	Papio anubis	79.37	0.00e+00	949.00
IUUC-Psi-093478	Pelodiscus sinensis	76.33	0.00e+00	888.00
IUUC-Pfo-097450	Poecilia formosa	90.61	0.00e+00	1038.00
IUUC-Pab-097618	Pongo abelii	79.55	0.00e+00	950.00
IUUC-Pte-104106	Pyrenophora teres	33.64	7.00e-11	60.80
IUUC-Sha-106935	Sarcophilus harrisii	81.87	0.00e+00	639.00
IUUC-Ssc-115599	Sus scrofa	80.00	0.00e+00	952.00
IUUC-Tgu-117001	Taeniopygia guttata	78.76	0.00e+00	914.00
IUUC-Tni-120888	Tetraodon nigroviridis	91.31	0.00e+00	1067.00
IUUC-Tbe-127285	Tupaia belangeri	67.18	3.00e-154	538.00
IUUC-Ttr-128574	Tursiops truncatus	63.41	0.00e+00	729.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence