iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000056842.6	ENSDART00000079402.5	ENSDARP00000073858.5
ENSDARG00000056842.6	ENSDART00000158613.1	ENSDARP00000135649.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-69	236.1	65	492

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ L+++p++ + l + ++++ ++++++e++++l++sl +l+++l     +++ + +   ll+al+ +  ++s++
   Q: 65   GLLNLGNTCFMNSLLQGLAACPSFIRWLEDFTSQNSADRERTERETQLSRSLMQLLKALSshdPGEDDVLDAGGLLEALRLYRWHISSF 153
           9*****************************999999999********************966666677899999*************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknk..........slisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E++++l ++leee   e++ ++ ++++ ++ e+s e++ek+ +  +              + F+g+l+s + c++c+++s + 
   Q: 154  EEQDAHELFHVLTSSLEEEQ--ERQPRVAHLFDMQTLEKSVESKEKNISCRSggplhpipslWRTRHPFHGRLTSYMACKRCEQQSpVH 240
           ******************99..679999999999999999998888888888999999987788899*******************999 PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqe...............aekklklkklPevLilhLkRfsf 239
           +++f +lsl++p+ +   + +l++cL++f + e++++   ++ce+c+k+q                 +k+lkl klP++L++hL+R ++
   Q: 241  YDSFDSLSLSIPSIQWGRPVTLDQCLQHFISSETIKE---VECENCTKQQAgelvngevlesqrttFVKQLKLGKLPQCLCIHLQRLTW 326
           ***********************************97...9******7777888888888888888*********************** PP
   S: 240  seeqksrekinkkvefpleLdls..pfctspeekqke.................................................... 274
           s+e +s++k +++v+f + L+l+  ++c+  +++qk+                                                    
   Q: 327  SKE-GSPIKRQEHVQFTEYLSLDryKHCSAAQSQQKTsrtnkakasadpkdkaiangvdsehcnnnkpqsngtfpsvflhspglssqln 414
           998.999**********9988883357777555555588899999999999999999999999999999999***************** PP
   S: 275  ........kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
                   ++ ++L+av+vH+G ++sGH+++y +           + +Wl ++D++V++ + +evl+   s+aY+lfY+r+
   Q: 415  ltydystsEYLFRLTAVLVHHGDMHSGHFITYRRCpaaprgtspFSSQWLWVSDDSVRKASLQEVLS---SSAYLLFYERM 492
           ******999**************************8888887777888*******************...*********96 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MPWCKQGTTD KLVREFLRTG AAARNKMMKN WGVIGGIAAA MAAGVYVLWG PISDRRKKRK 60
GMVPGLLNLG NTCFMNSLLQ GLAACPSFIR WLEDFTSQNS ADRERTERET QLSRSLMQLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTGAAATA TGCCTTGGTG CAAGCAAGGA ACTACAGACA AGCTTGTACG AGAGTTTTTA 60
CGCACTGGGG CCGCTGCAAG GTTAGAGTTT ACATGAAAAC GCATGATTTG ACGGCTGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	27.08	1.00e-19	90.90
IUUC-Aml-001733	Ailuropoda melanoleuca	58.38	6.00e-153	534.00
IUUC-Atr-002510	Amborella trichopoda	25.33	5.00e-24	106.00
IUUC-Apl-003645	Anas platyrhynchos	56.57	1.00e-80	292.00
IUUC-Aca-004583	Anolis carolinensis	65.67	2.00e-22	96.70
IUUC-Aly-005754	Arabidopsis lyrata	27.77	5.00e-25	108.00
IUUC-Ath-007622	Arabidopsis thaliana	27.85	2.00e-27	117.00
IUUC-Acl-008136	Aspergillus clavatus	21.69	3.00e-16	80.50
IUUC-Afl-008530	Aspergillus flavus	23.50	8.00e-14	72.40
IUUC-Afu-009119	Aspergillus fumigatus	21.95	4.00e-14	73.60
IUUC-Ani-009286	Aspergillus nidulans	23.54	2.00e-15	77.80
IUUC-Aor-009934	Aspergillus oryzae	23.39	1.00e-13	71.60
IUUC-Ate-010439	Aspergillus terreus	23.83	3.00e-17	84.00
IUUC-Ame-010896	Astyanax mexicanus	82.46	0.00e+00	776.00
IUUC-Bta-012321	Bos taurus	59.47	1.00e-153	536.00
IUUC-Bci-013590	Botrytis cinerea	22.29	7.00e-18	86.30
IUUC-Bdi-014795	Brachypodium distachyon	25.73	2.00e-21	96.70
IUUC-Bol-015637	Brassica oleracea	27.00	1.00e-24	107.00
IUUC-Bra-016801	Brassica rapa	26.62	4.00e-25	109.00
IUUC-Cel-018308	Caenorhabditis elegans	27.97	8.00e-38	151.00
IUUC-Cja-018826	Callithrix jacchus	60.37	5.00e-158	551.00
IUUC-Cfa-021206	Canis familiaris	57.40	1.00e-150	526.00
IUUC-Cpo-021343	Cavia porcellus	59.35	1.00e-154	539.00
IUUC-Csa-023419	Chlorocebus sabaeus	60.57	4.00e-158	551.00
IUUC-Cho-024475	Choloepus hoffmanni	50.71	6.00e-77	281.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	21.61	6.00e-16	79.70
IUUC-Cne-027061	Cryptococcus neoformans	26.12	8.00e-15	75.90
IUUC-Dno-029929	Dasypus novemcinctus	58.87	2.00e-155	542.00
IUUC-Dor-030166	Dipodomys ordii	51.38	2.00e-127	449.00
IUUC-Dse-031252	Dothistroma septosporum	24.06	3.00e-14	73.60
IUUC-Dme-031627	Drosophila melanogaster	31.37	1.00e-34	141.00
IUUC-Ete-032634	Echinops telfairi	56.82	3.00e-144	505.00
IUUC-Eca-033968	Equus caballus	58.79	1.00e-151	530.00
IUUC-Fca-036525	Felis catus	58.86	1.00e-157	549.00
IUUC-Fal-036606	Ficedula albicollis	58.86	7.00e-125	440.00
IUUC-Fso-038309	Fusarium solani	22.42	6.00e-13	69.30
IUUC-Gmo-038726	Gadus morhua	65.94	1.00e-175	609.00
IUUC-Gga-040718	Gallus gallus	60.16	1.00e-123	436.00
IUUC-Gac-042645	Gasterosteus aculeatus	68.61	0.00e+00	644.00
IUUC-Gma-042890	Glycine max	24.49	7.00e-23	102.00
IUUC-Ggo-045021	Gorilla gorilla	60.37	4.00e-158	551.00
IUUC-Hsa-045832	Homo sapiens	60.37	4.00e-158	551.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	59.58	6.00e-151	527.00
IUUC-Kpa-049268	Komagataella pastoris	21.88	3.00e-20	93.20
IUUC-Lch-050662	Latimeria chalumnae	63.48	7.00e-166	577.00
IUUC-Lpe-051078	Leersia perrieri	26.58	5.00e-29	122.00
IUUC-Loc-052611	Lepisosteus oculatus	67.12	0.00e+00	651.00
IUUC-Lma-053048	Leptosphaeria maculans	21.00	2.00e-15	77.80
IUUC-Laf-053752	Loxodonta africana	59.54	1.00e-151	529.00
IUUC-Mcc-054892	Macaca mulatta	60.16	6.00e-158	550.00
IUUC-Meu-056673	Macropus eugenii	56.71	4.00e-109	387.00
IUUC-Mor-057143	Magnaporthe oryzae	23.33	2.00e-14	74.30
IUUC-Mtr-057976	Medicago truncatula	26.28	4.00e-33	136.00
IUUC-Mla-058970	Melampsora laricipopulina	25.36	7.00e-25	108.00
IUUC-Mga-059543	Meleagris gallopavo	59.54	3.00e-144	504.00
IUUC-Mmr-061534	Microcebus murinus	58.33	7.00e-158	550.00
IUUC-Mdo-062140	Monodelphis domestica	54.15	1.00e-127	449.00
IUUC-Mmu-063673	Mus musculus	58.44	5.00e-152	531.00
IUUC-Mpu-066328	Mustela putorius furo	60.25	2.00e-156	545.00
IUUC-Mlu-067938	Myotis lucifugus	59.07	3.00e-160	558.00
IUUC-Nfi-068306	Neosartorya fischeri	20.80	3.00e-14	73.60
IUUC-Nle-069426	Nomascus leucogenys	58.60	1.00e-138	486.00
IUUC-Opr-070796	Ochotona princeps	54.22	1.00e-67	251.00
IUUC-Ont-072248	Oreochromis niloticus	72.23	0.00e+00	681.00
IUUC-Oan-072916	Ornithorhynchus anatinus	62.87	8.00e-162	563.00
IUUC-Ocu-074459	Oryctolagus cuniculus	55.61	9.00e-120	423.00
IUUC-Oba-075765	Oryza barthii	26.22	4.00e-31	129.00
IUUC-Obr-076005	Oryza brachyantha	26.29	2.00e-32	134.00
IUUC-Ogl-077916	Oryza glaberrima	26.73	3.00e-36	146.00
IUUC-Ogu-078263	Oryza glumaepatula	26.42	2.00e-32	133.00
IUUC-Oin-080096	Oryza indica	27.02	8.00e-24	105.00
IUUC-Ome-081928	Oryza meridionalis	26.90	3.00e-32	133.00
IUUC-Oni-082424	Oryza nivara	26.22	3.00e-32	133.00
IUUC-Oru-085117	Oryza rufipogon	26.22	3.00e-32	133.00
IUUC-Ola-087429	Oryzias latipes	68.47	9.00e-173	600.00
IUUC-Oga-087981	Otolemur garnettii	59.26	4.00e-158	551.00
IUUC-Oar-089927	Ovis aries	59.67	2.00e-154	538.00
IUUC-Ptr-090878	Pan troglodytes	60.37	4.00e-158	551.00
IUUC-Pan-092698	Papio anubis	60.16	6.00e-158	550.00
IUUC-Psi-093451	Pelodiscus sinensis	62.11	2.00e-159	555.00
IUUC-Pfo-096096	Poecilia formosa	70.12	0.00e+00	644.00
IUUC-Pab-098676	Pongo abelii	59.96	6.00e-155	540.00
IUUC-Ppe-101898	Prunus persica	24.08	1.00e-23	105.00
IUUC-Pva-103018	Pteropus vampyrus	58.08	8.00e-150	523.00
IUUC-Pgr-103686	Puccinia graminis	22.69	2.00e-13	71.60
IUUC-Pte-104330	Pyrenophora teres	23.00	3.00e-17	84.00
IUUC-Pyt-104518	Pyrenophora triticirepentis	23.67	3.00e-20	94.00
IUUC-Rno-105708	Rattus norvegicus	58.02	3.00e-151	528.00
IUUC-Sha-106971	Sarcophilus harrisii	61.32	4.00e-161	561.00
IUUC-Ssl-108648	Sclerotinia sclerotiorum	22.71	8.00e-19	89.40
IUUC-Sit-110442	Setaria italica	26.25	1.00e-29	124.00
IUUC-Ssc-116397	Sus scrofa	57.11	4.00e-151	528.00
IUUC-Tgu-117446	Taeniopygia guttata	59.04	6.00e-158	550.00
IUUC-Tru-118268	Takifugu rubripes	66.13	2.00e-169	588.00
IUUC-Tsy-119484	Tarsius syrichta	72.83	2.00e-29	124.00
IUUC-Tni-119735	Tetraodon nigroviridis	62.80	3.00e-147	514.00
IUUC-Tca-121660	Theobroma cacao	27.03	4.00e-31	129.00
IUUC-Tae-125203	Triticum aestivum	25.78	6.00e-29	122.00
IUUC-Tur-126458	Triticum urartu	26.48	5.00e-28	119.00
IUUC-Tbe-127740	Tupaia belangeri	54.47	2.00e-135	475.00
IUUC-Ttr-129273	Tursiops truncatus	59.05	1.00e-151	529.00
IUUC-Vda-129789	Verticillium dahliae	22.10	2.00e-09	58.20
IUUC-Vvi-131177	Vitis vinifera	25.91	2.00e-28	120.00
IUUC-Xtr-132374	Xenopus tropicalis	60.80	4.00e-164	571.00
IUUC-Xma-133267	Xiphophorus maculatus	70.40	0.00e+00	684.00
IUUC-Yli-134571	Yarrowia lipolytica	21.81	3.00e-13	70.50
IUUC-Zma-135796	Zea mays	26.01	4.00e-31	129.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence