iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000001536.4	ENSCAFT00000050000.2	ENSCAFP00000038652.1
ENSCAFG00000001536.4	ENSCAFT00000002395.4	ENSCAFP00000002217.3
ENSCAFG00000001536.4	ENSCAFT00000045304.1	ENSCAFP00000036479.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	4.20e-13	48.9	328	356
ULD/UDP/UBQ/UBQ_Other	6.60e-14	51.9	211	272

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 2    eaqWaCsaCTflNePeavkCemCsrpRgc 30
           +++W+C++CTf+N+P++++CemCs++++c
   Q: 328  QPGWSCPSCTFINAPSRPGCEMCSTQKPC 356
           689*************************9 PP

ULD/UDP/UBQ/UBQ_Other

   S: 2    qvtvksldgs.eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglk 62
           qvtv+++ +s + +l+v+p++t+a+L+e++++++g+pp+ qr+++ G++L  + ++La+yg++
   Q: 211  QVTVEDAASSaHVSLQVHPHCTIATLQEQVFSEFGFPPAVQRWVI-GQCLcVPERSLASYGVR 272
           89*******************************************.**************995 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAPPSGPGPA AVLLAVQATV RPLGAGPDAE AQLRRLQLSA DPERPGRLRL QLLGAGPGAG 60
GSEWPLESVS YTVRGPSRHE LQPPPGGPGA LSLHFLDARD ARRWAALVRR AAMEGRDGSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAGCCTCGG GCCCTCAGTC TGTGCCTCCT GCCGGGTGGA AAGGGCCTGT GGTGTCTGTG 60
CCCTCCCCTC CCCTCACAGT GTCTCTGGCT TCTCCATCCA CCCCTGGGGG CGACGGGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR031912--Sharpin_PH
IPR029071--Ubiquitin-rel_dom
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF16764--Sharpin_PH
PF00641--zf-RanBP

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0005829--C:cytosol
GO:0071797--C:LUBAC complex
GO:0043130--F:ubiquitin binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0030262--P:apoptotic nuclear changes
GO:0031424--P:keratinization
GO:0007005--P:mitochondrion organization
GO:0050728--P:negative regulation of inflammatory response
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:2000348--P:regulation of CD40 signaling pathway
GO:0010803--P:regulation of tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001223	Ailuropoda melanoleuca	85.60	1.00e-141	496.00
IUUC-Apl-004151	Anas platyrhynchos	52.78	2.00e-19	86.30
IUUC-Bta-012948	Bos taurus	75.31	2.00e-135	475.00
IUUC-Cja-019031	Callithrix jacchus	77.72	1.00e-118	419.00
IUUC-Cpo-022499	Cavia porcellus	69.92	2.00e-112	398.00
IUUC-Csa-023641	Chlorocebus sabaeus	69.53	2.00e-108	385.00
IUUC-Dre-027612	Danio rerio	37.75	4.00e-40	158.00
IUUC-Dno-029459	Dasypus novemcinctus	61.45	6.00e-59	221.00
IUUC-Dor-030914	Dipodomys ordii	57.32	6.00e-76	277.00
IUUC-Ete-032940	Echinops telfairi	70.57	7.00e-97	347.00
IUUC-Eca-033537	Equus caballus	80.92	4.00e-128	451.00
IUUC-Eeu-035176	Erinaceus europaeus	64.80	9.00e-56	210.00
IUUC-Fca-035971	Felis catus	77.26	6.00e-135	473.00
IUUC-Gmo-039219	Gadus morhua	37.30	4.00e-48	185.00
IUUC-Gga-040198	Gallus gallus	44.79	3.00e-30	125.00
IUUC-Ggo-044678	Gorilla gorilla	72.25	2.00e-110	392.00
IUUC-Hsa-046578	Homo sapiens	74.93	1.00e-114	405.00
IUUC-Itr-047913	Ictidomys tridecemlineatus	70.41	3.00e-123	434.00
IUUC-Mcc-055686	Macaca mulatta	69.04	1.00e-110	393.00
IUUC-Meu-055912	Macropus eugenii	55.00	2.00e-62	232.00
IUUC-Mmr-060584	Microcebus murinus	74.25	3.00e-123	434.00
IUUC-Mdo-062191	Monodelphis domestica	56.23	3.00e-85	308.00
IUUC-Mmu-063740	Mus musculus	68.42	8.00e-101	360.00
IUUC-Mpu-066878	Mustela putorius furo	77.08	5.00e-125	440.00
IUUC-Mlu-067878	Myotis lucifugus	80.33	6.00e-128	450.00
IUUC-Nle-069748	Nomascus leucogenys	74.44	4.00e-104	370.00
IUUC-Ont-072270	Oreochromis niloticus	39.78	5.00e-50	191.00
IUUC-Oga-088300	Otolemur garnettii	72.73	7.00e-126	443.00
IUUC-Oar-089549	Ovis aries	76.28	4.00e-139	487.00
IUUC-Ptr-090961	Pan troglodytes	75.92	4.00e-102	364.00
IUUC-Pan-092687	Papio anubis	72.60	1.00e-110	393.00
IUUC-Pfo-096865	Poecilia formosa	35.05	4.00e-41	162.00
IUUC-Pab-097872	Pongo abelii	72.46	3.00e-103	368.00
IUUC-Pca-100363	Procavia capensis	68.09	8.00e-61	227.00
IUUC-Pva-102595	Pteropus vampyrus	77.40	4.00e-106	377.00
IUUC-Rno-105856	Rattus norvegicus	66.95	4.00e-95	341.00
IUUC-Sha-106838	Sarcophilus harrisii	54.11	4.00e-77	281.00
IUUC-Ssl-108588	Sclerotinia sclerotiorum	38.71	3.60e-02	32.70
IUUC-Sly-111366	Solanum lycopersicum	39.29	2.00e-05	43.10
IUUC-Sar-113611	Sorex araneus	68.13	3.00e-25	108.00
IUUC-Ssc-116263	Sus scrofa	77.86	2.00e-139	488.00
IUUC-Tni-120004	Tetraodon nigroviridis	41.19	3.00e-48	185.00
IUUC-Tbe-127471	Tupaia belangeri	66.46	2.00e-91	329.00
IUUC-Ttr-128534	Tursiops truncatus	64.52	1.00e-94	339.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence