iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001188

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 ubiquitin-protein ligase RFWD3

Genbank Nucleotide ID

ACTA01108434

Gene Name

RFWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000001323.1	ENSAMET00000001443.1	ENSAMEP00000001391.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-07	29.5	512	550

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllk 37
           H   +++laf   + +ll+s+s D t+k+ +l t+++++
   Q: 512  HGKQIRGLAFssRSkGLLLSASLDSTVKLTSLETNTVVQ 550
           8889******99446*************98888877766 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

SEIEVLEDLD MIISEMAQEA MEYNVDEQLE HRVAEQPVPA EVVSTQGGPP PLQPLPTEVV 60
SSQGAPPLLQ PAPAEGTSSQ VGPHLLQPAA QLSVDLTEEV ELLGEDRVEN INPGASEEHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTGAAATAG AAGTTCTAGA AGACTTAGAT ATGATTATAT CAGCTATATG GCATGTTTTA 60
TCTGTTTTAC TGATACTTTT TACGAATCTT CTCCAGAGAT GGCTCAGGAA GCAATGGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0035861--C:site of double-strand break
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:2000001--P:regulation of DNA damage checkpoint
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000929	Aegilops tauschii	25.85	4.00e-16	79.70
IUUC-Atr-003034	Amborella trichopoda	29.33	3.00e-19	89.40
IUUC-Apl-003182	Anas platyrhynchos	70.87	0.00e+00	734.00
IUUC-Aca-004619	Anolis carolinensis	62.24	0.00e+00	759.00
IUUC-Aly-006391	Arabidopsis lyrata	27.71	5.00e-34	139.00
IUUC-Ath-007300	Arabidopsis thaliana	25.60	1.00e-31	131.00
IUUC-Ame-010890	Astyanax mexicanus	60.04	5.00e-180	624.00
IUUC-Bta-013051	Bos taurus	73.47	0.00e+00	1087.00
IUUC-Bdi-014519	Brachypodium distachyon	26.98	1.00e-20	94.40
IUUC-Bol-015271	Brassica oleracea	31.21	2.00e-33	136.00
IUUC-Bra-017931	Brassica rapa	31.41	2.00e-32	133.00
IUUC-Cja-019240	Callithrix jacchus	77.69	0.00e+00	1090.00
IUUC-Cfa-021010	Canis familiaris	86.47	0.00e+00	1253.00
IUUC-Cpo-022308	Cavia porcellus	73.19	0.00e+00	989.00
IUUC-Csa-023501	Chlorocebus sabaeus	78.08	0.00e+00	1161.00
IUUC-Cho-024900	Choloepus hoffmanni	72.49	0.00e+00	1017.00
IUUC-Cin-025403	Ciona intestinalis	38.03	1.00e-96	347.00
IUUC-Csv-025819	Ciona savignyi	37.60	8.00e-44	170.00
IUUC-Cme-027123	Cyanidioschyzon merolae	25.50	2.00e-17	84.00
IUUC-Dre-028354	Danio rerio	57.55	4.00e-167	581.00
IUUC-Dno-029400	Dasypus novemcinctus	76.46	0.00e+00	1099.00
IUUC-Dor-030320	Dipodomys ordii	71.50	0.00e+00	826.00
IUUC-Dme-031949	Drosophila melanogaster	27.33	7.00e-44	171.00
IUUC-Ete-032691	Echinops telfairi	58.87	1.00e-138	487.00
IUUC-Eca-034320	Equus caballus	83.66	0.00e+00	1239.00
IUUC-Fca-035732	Felis catus	85.27	0.00e+00	1179.00
IUUC-Fal-036648	Ficedula albicollis	62.42	0.00e+00	745.00
IUUC-Gmo-038609	Gadus morhua	56.56	6.00e-139	487.00
IUUC-Gga-040522	Gallus gallus	71.32	5.00e-110	391.00
IUUC-Gac-042318	Gasterosteus aculeatus	55.16	4.00e-132	464.00
IUUC-Gma-043184	Glycine max	25.50	4.00e-25	109.00
IUUC-Ggo-044464	Gorilla gorilla	78.46	0.00e+00	1155.00
IUUC-Hsa-045991	Homo sapiens	78.72	0.00e+00	1152.00
IUUC-Hvu-047705	Hordeum vulgare	23.80	2.00e-26	114.00
IUUC-Itr-047977	Ictidomys tridecemlineatus	79.75	0.00e+00	1175.00
IUUC-Lch-050112	Latimeria chalumnae	66.86	0.00e+00	682.00
IUUC-Lpe-051605	Leersia perrieri	27.44	7.00e-20	92.40
IUUC-Loc-052241	Lepisosteus oculatus	63.05	0.00e+00	646.00
IUUC-Laf-054559	Loxodonta africana	80.77	0.00e+00	1013.00
IUUC-Mcc-055093	Macaca mulatta	77.95	0.00e+00	1150.00
IUUC-Meu-056417	Macropus eugenii	67.19	0.00e+00	697.00
IUUC-Mtr-058533	Medicago truncatula	24.00	7.00e-29	122.00
IUUC-Mga-059498	Meleagris gallopavo	69.96	0.00e+00	707.00
IUUC-Mmr-061782	Microcebus murinus	80.25	0.00e+00	1155.00
IUUC-Mdo-062053	Monodelphis domestica	63.62	0.00e+00	827.00
IUUC-Mmu-063352	Mus musculus	66.12	0.00e+00	997.00
IUUC-Mac-064582	Musa acuminata	25.99	2.00e-19	90.90
IUUC-Mpu-066087	Mustela putorius furo	90.72	0.00e+00	1297.00
IUUC-Mlu-068147	Myotis lucifugus	78.10	0.00e+00	1065.00
IUUC-Nle-069503	Nomascus leucogenys	74.74	0.00e+00	1083.00
IUUC-Opr-070479	Ochotona princeps	67.91	0.00e+00	973.00
IUUC-Ont-071700	Oreochromis niloticus	57.23	2.00e-168	585.00
IUUC-Oan-073702	Ornithorhynchus anatinus	74.44	0.00e+00	789.00
IUUC-Ocu-074886	Oryctolagus cuniculus	74.26	0.00e+00	1108.00
IUUC-Oba-075729	Oryza barthii	28.41	4.00e-24	106.00
IUUC-Obr-076562	Oryza brachyantha	28.21	1.00e-21	97.40
IUUC-Ogl-077615	Oryza glaberrima	28.41	4.00e-24	106.00
IUUC-Ogu-078921	Oryza glumaepatula	27.83	1.00e-24	108.00
IUUC-Oin-079250	Oryza indica	25.71	3.00e-18	86.70
IUUC-Olo-080758	Oryza longistaminata	28.15	8.00e-23	101.00
IUUC-Ome-081707	Oryza meridionalis	26.35	4.00e-20	93.20
IUUC-Oni-083006	Oryza nivara	26.98	2.00e-24	107.00
IUUC-Opu-083650	Oryza punctata	29.90	2.00e-24	107.00
IUUC-Oru-084924	Oryza rufipogon	27.65	7.00e-25	108.00
IUUC-Osa-085820	Oryza sativa	27.83	2.00e-24	107.00
IUUC-Ola-087229	Oryzias latipes	56.19	2.00e-135	474.00
IUUC-Oga-088243	Otolemur garnettii	79.03	0.00e+00	1069.00
IUUC-Oar-089461	Ovis aries	78.87	0.00e+00	1166.00
IUUC-Ptr-090527	Pan troglodytes	78.59	0.00e+00	1147.00
IUUC-Pan-092431	Papio anubis	77.90	0.00e+00	1081.00
IUUC-Psi-093156	Pelodiscus sinensis	71.26	0.00e+00	776.00
IUUC-Pno-094897	Phaeosphaeria nodorum	22.73	6.00e-08	51.60
IUUC-Ppa-095305	Physcomitrella patens	39.82	1.00e-19	92.00
IUUC-Pfo-097065	Poecilia formosa	58.73	2.00e-166	579.00
IUUC-Pab-098272	Pongo abelii	78.33	0.00e+00	1168.00
IUUC-Pop-099827	Populus trichocarpa	29.81	3.00e-30	126.00
IUUC-Pca-100713	Procavia capensis	70.12	0.00e+00	947.00
IUUC-Ppe-102103	Prunus persica	26.43	3.00e-33	136.00
IUUC-Pva-103133	Pteropus vampyrus	87.89	0.00e+00	773.00
IUUC-Pte-104191	Pyrenophora teres	50.00	3.00e-08	52.80
IUUC-Pyt-104734	Pyrenophora triticirepentis	48.00	5.00e-08	52.00
IUUC-Sha-107628	Sarcophilus harrisii	74.09	0.00e+00	779.00
IUUC-Sit-109781	Setaria italica	30.45	4.00e-26	112.00
IUUC-Sly-111779	Solanum lycopersicum	29.29	4.00e-31	129.00
IUUC-Stu-112817	Solanum tuberosum	42.48	2.00e-18	86.30
IUUC-Sar-113124	Sorex araneus	65.85	0.00e+00	705.00
IUUC-Sbi-114107	Sorghum bicolor	25.68	1.00e-28	121.00
IUUC-Ssc-115850	Sus scrofa	77.81	0.00e+00	1150.00
IUUC-Tgu-117295	Taeniopygia guttata	71.40	0.00e+00	755.00
IUUC-Tru-117539	Takifugu rubripes	56.67	5.00e-167	580.00
IUUC-Tsy-118805	Tarsius syrichta	56.04	4.00e-114	405.00
IUUC-Tni-120274	Tetraodon nigroviridis	58.20	7.00e-167	580.00
IUUC-Tca-121162	Theobroma cacao	30.46	9.00e-31	128.00
IUUC-Tae-124822	Triticum aestivum	24.95	2.00e-27	117.00
IUUC-Tur-126162	Triticum urartu	25.09	5.00e-17	83.20
IUUC-Tbe-127884	Tupaia belangeri	72.00	4.00e-81	295.00
IUUC-Ttr-128665	Tursiops truncatus	73.14	7.00e-150	524.00
IUUC-Vpa-130385	Vicugna pacos	84.17	0.00e+00	1179.00
IUUC-Vvi-131464	Vitis vinifera	25.43	3.00e-24	106.00
IUUC-Xtr-132015	Xenopus tropicalis	61.80	0.00e+00	727.00
IUUC-Xma-133109	Xiphophorus maculatus	58.12	3.00e-165	575.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence