iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020274

Ensembl Protein ID

ENSCAFP00000026519.3

UniProt Accession

E2RCG3; E2RCG3_CANLF

Genbank Protein ID

ENSCAFP00000026519

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03003091

Gene Name

TNIP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000017954.3	ENSCAFT00000028510.3	ENSCAFP00000026519.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	1.10e-24	86.4	452	512

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslkask 61
           k+el++++e+LkqQv+i++eDFq+ER+dREr+neekeeL++qveklq+qv+++n++lka+k
   Q: 452  KQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFK 512
           699*******************************************************986 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MEGRGPYRIY DPGGGVPLGE ASAAFERLVE ENSRLKEKMQ GIKMLGELLE ESQMEASRLR 60
QKAEELVKDS DLLPPPSPSL TSFDHLAELT GKDAGVPAPP ADPAHPSDKS QPVPKPPSSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCCTCCCC TTCCCCGGAA TGCTTGACAA GTGATAGTCT GGGAAGTGAC AGGTGGAACT 60
GACAAGGGCC CTGTGCTCTG CCAGGGGGCA GGATGGGGCC TCAGCTGGGC CTTGTGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR033372--TNIP1

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0009101--P:glycoprotein biosynthetic process
GO:0007159--P:leukocyte cell-cell adhesion
GO:0085032--P:modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade
GO:0002755--P:MyD88-dependent toll-like receptor signaling pathway
GO:0070373--P:negative regulation of ERK1 and ERK2 cascade
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050727--P:regulation of inflammatory response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002103	Ailuropoda melanoleuca	92.13	0.00e+00	936.00
IUUC-Apl-004176	Anas platyrhynchos	56.29	1.00e-165	576.00
IUUC-Aca-004362	Anolis carolinensis	57.07	6.00e-153	534.00
IUUC-Ate-010509	Aspergillus terreus	23.68	1.30e-02	35.00
IUUC-Ame-011307	Astyanax mexicanus	40.13	1.00e-91	330.00
IUUC-Bta-012620	Bos taurus	88.53	0.00e+00	793.00
IUUC-Cja-018996	Callithrix jacchus	88.85	0.00e+00	955.00
IUUC-Cpo-021786	Cavia porcellus	84.70	0.00e+00	908.00
IUUC-Csa-023236	Chlorocebus sabaeus	88.87	0.00e+00	873.00
IUUC-Cho-024535	Choloepus hoffmanni	69.47	6.00e-103	368.00
IUUC-Cin-025355	Ciona intestinalis	32.41	2.00e-10	61.20
IUUC-Dre-028725	Danio rerio	45.75	2.00e-119	422.00
IUUC-Dno-028967	Dasypus novemcinctus	88.64	1.00e-119	422.00
IUUC-Dor-030761	Dipodomys ordii	83.51	1.00e-109	390.00
IUUC-Ete-032695	Echinops telfairi	73.05	0.00e+00	795.00
IUUC-Eca-033655	Equus caballus	89.61	0.00e+00	957.00
IUUC-Eeu-035335	Erinaceus europaeus	67.32	8.00e-104	370.00
IUUC-Fca-035597	Felis catus	93.54	0.00e+00	1001.00
IUUC-Fal-037020	Ficedula albicollis	54.44	4.00e-149	521.00
IUUC-Gga-040812	Gallus gallus	54.80	5.00e-156	544.00
IUUC-Ggo-045345	Gorilla gorilla	87.62	0.00e+00	932.00
IUUC-Hsa-045785	Homo sapiens	88.87	0.00e+00	954.00
IUUC-Itr-048029	Ictidomys tridecemlineatus	87.60	0.00e+00	968.00
IUUC-Lch-049745	Latimeria chalumnae	54.97	4.00e-122	431.00
IUUC-Loc-052635	Lepisosteus oculatus	49.04	2.00e-137	483.00
IUUC-Laf-053625	Loxodonta africana	81.76	0.00e+00	847.00
IUUC-Mcc-055730	Macaca mulatta	89.18	0.00e+00	913.00
IUUC-Meu-056550	Macropus eugenii	71.01	2.00e-112	399.00
IUUC-Mpo-057394	Magnaporthe poae	36.00	5.40e-02	33.50
IUUC-Mtr-058001	Medicago truncatula	29.85	2.70e-01	28.50
IUUC-Mga-059948	Meleagris gallopavo	68.63	2.00e-73	268.00
IUUC-Mmr-060900	Microcebus murinus	87.74	0.00e+00	986.00
IUUC-Mdo-061805	Monodelphis domestica	70.91	0.00e+00	798.00
IUUC-Mmu-063749	Mus musculus	81.33	0.00e+00	839.00
IUUC-Mpu-065979	Mustela putorius furo	91.50	0.00e+00	1017.00
IUUC-Mlu-067100	Myotis lucifugus	87.36	0.00e+00	923.00
IUUC-Nle-069667	Nomascus leucogenys	89.34	0.00e+00	930.00
IUUC-Opr-070478	Ochotona princeps	81.63	0.00e+00	903.00
IUUC-Ont-071777	Oreochromis niloticus	45.02	3.00e-106	379.00
IUUC-Oan-073239	Ornithorhynchus anatinus	66.67	0.00e+00	734.00
IUUC-Ocu-073879	Oryctolagus cuniculus	88.05	0.00e+00	889.00
IUUC-Oga-088900	Otolemur garnettii	90.88	0.00e+00	1045.00
IUUC-Oar-089444	Ovis aries	84.78	0.00e+00	852.00
IUUC-Ptr-090641	Pan troglodytes	88.87	0.00e+00	956.00
IUUC-Pan-092283	Papio anubis	89.00	0.00e+00	892.00
IUUC-Psi-092967	Pelodiscus sinensis	53.34	2.00e-159	555.00
IUUC-Pma-094726	Petromyzon marinus	33.27	5.00e-50	192.00
IUUC-Pfo-096085	Poecilia formosa	44.10	1.00e-106	380.00
IUUC-Pab-097976	Pongo abelii	84.19	0.00e+00	890.00
IUUC-Pca-100215	Procavia capensis	77.61	0.00e+00	746.00
IUUC-Pva-102258	Pteropus vampyrus	84.57	0.00e+00	921.00
IUUC-Rno-105833	Rattus norvegicus	79.54	0.00e+00	807.00
IUUC-Sly-111729	Solanum lycopersicum	27.88	6.00e-04	40.00
IUUC-Stu-112653	Solanum tuberosum	26.27	2.00e-04	41.20
IUUC-Ssc-115652	Sus scrofa	86.77	0.00e+00	893.00
IUUC-Tgu-116648	Taeniopygia guttata	53.89	4.00e-134	471.00
IUUC-Tru-118455	Takifugu rubripes	45.09	1.00e-107	384.00
IUUC-Tbe-128129	Tupaia belangeri	85.60	2.00e-104	373.00
IUUC-Ttr-128305	Tursiops truncatus	83.31	0.00e+00	811.00
IUUC-Xtr-131842	Xenopus tropicalis	48.58	9.00e-128	450.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence