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Tag Content
UUCD2 ID IUUC-Gga-040828
UUCD1 version UUC-GaG-00445
Ensembl Protein ID ENSGALP00000053163.1
UniProt Accession A0A1D5PK13; A0A1D5PK13_CHICK
Genbank Protein ID ENSGALP00000053163
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AADN04000116
Gene Name KMT2A
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGALG00000006818.5 ENSGALT00000046314.1 ENSGALP00000053163.1
ENSGALG00000006818.5 ENSGALT00000011022.5 ENSGALP00000011008.5
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 5.40e-26 90.9 1457 1510
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           k+C+vCg++++ +k+l+eC+kCr+ +Hp+Cl+++ ++++p+++k  wiC+kC ++
   Q: 1457 KFCHVCGRQHQATKQLLECNKCRNSYHPECLGPN-YPTKPTKKKkvWICTKCVRC 1510
           58********************************.*****99999*******876 PP
   
Organism Gallus gallus
Protein Sequence
(Fasta)
MAHSGRWRFP ARPGSGGWGR RGLGGSRLRV PAHPRSAPAG GTPPARAAPA RAAGHTYRRA 60
PPPGQCAAGG CRPPSSASAP RGPSPRTRLA AGVSSPPPPP LSSSRERGCV FVLKWGGSGD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Gga-040828|E3,PHD|Gallus gallus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCGCACA GCGGTCGGTG GCGCTTCCCT GCCCGGCCCG GCAGCGGCGG ATGGGGCCGC 60
CGGGGGCTGG GGGGGTCCCG GCTGCGGGTG CCGGCCGTGC GGAGCCTGCG AGCGGCCGAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Gga-040828|E3,PHD|Gallus gallus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR016569--MeTrfase_trithorax
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50014--BROMODOMAIN_2
PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC
SMART

SM00297--BROMO
SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET
Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0003677--F:DNA binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001054 Aegilops tauschii 34.74 7.00e-13 69.30
IUUC-Aml-002274 Ailuropoda melanoleuca 79.42 0.00e+00 4972.00
IUUC-Atr-002455 Amborella trichopoda 48.10 1.00e-39 158.00
IUUC-Apl-003478 Anas platyrhynchos 93.28 0.00e+00 4760.00
IUUC-Aca-005086 Anolis carolinensis 67.92 0.00e+00 3727.00
IUUC-Aly-006448 Arabidopsis lyrata 38.75 5.00e-41 162.00
IUUC-Ath-006690 Arabidopsis thaliana 47.40 1.00e-37 152.00
IUUC-Ame-011195 Astyanax mexicanus 45.02 0.00e+00 833.00
IUUC-Bta-012974 Bos taurus 78.87 0.00e+00 4992.00
IUUC-Bdi-014882 Brachypodium distachyon 33.17 1.00e-25 110.00
IUUC-Bol-016540 Brassica oleracea 48.05 3.00e-38 154.00
IUUC-Cja-019226 Callithrix jacchus 78.58 0.00e+00 4989.00
IUUC-Cfa-021049 Canis familiaris 79.89 0.00e+00 4997.00
IUUC-Cpo-021459 Cavia porcellus 79.78 0.00e+00 3594.00
IUUC-Cre-022891 Chlamydomonas reinhardtii 50.78 2.00e-39 159.00
IUUC-Csa-023434 Chlorocebus sabaeus 79.61 0.00e+00 4611.00
IUUC-Cho-024652 Choloepus hoffmanni 75.93 0.00e+00 3239.00
IUUC-Cin-025724 Ciona intestinalis 54.78 4.00e-96 346.00
IUUC-Csv-026268 Ciona savignyi 36.28 2.00e-131 464.00
IUUC-Cme-027224 Cyanidioschyzon merolae 34.18 2.00e-12 68.20
IUUC-Dre-028180 Danio rerio 65.91 0.00e+00 1148.00
IUUC-Dno-029068 Dasypus novemcinctus 76.55 0.00e+00 4705.00
IUUC-Dor-030550 Dipodomys ordii 75.67 0.00e+00 4328.00
IUUC-Dme-032023 Drosophila melanogaster 46.82 5.00e-91 330.00
IUUC-Ete-032834 Echinops telfairi 69.72 0.00e+00 2218.00
IUUC-Eca-033615 Equus caballus 79.66 0.00e+00 4873.00
IUUC-Eeu-035136 Erinaceus europaeus 75.80 0.00e+00 1051.00
IUUC-Fca-036453 Felis catus 71.39 0.00e+00 1967.00
IUUC-Fal-037256 Ficedula albicollis 91.03 0.00e+00 5886.00
IUUC-Gmo-038641 Gadus morhua 67.75 0.00e+00 1097.00
IUUC-Gac-041452 Gasterosteus aculeatus 70.57 0.00e+00 1164.00
IUUC-Gma-043554 Glycine max 49.02 5.00e-39 156.00
IUUC-Ggo-045124 Gorilla gorilla 76.12 0.00e+00 4660.00
IUUC-Hsa-046143 Homo sapiens 79.25 0.00e+00 4906.00
IUUC-Hvu-047762 Hordeum vulgare 28.89 9.00e-19 88.20
IUUC-Itr-049024 Ictidomys tridecemlineatus 77.26 0.00e+00 4274.00
IUUC-Lch-049704 Latimeria chalumnae 66.39 0.00e+00 3978.00
IUUC-Lpe-051476 Leersia perrieri 30.41 1.00e-21 98.60
IUUC-Loc-052181 Lepisosteus oculatus 78.85 0.00e+00 1298.00
IUUC-Laf-053946 Loxodonta africana 80.31 0.00e+00 4860.00
IUUC-Mcc-055508 Macaca mulatta 78.41 0.00e+00 4908.00
IUUC-Meu-056485 Macropus eugenii 76.12 0.00e+00 2774.00
IUUC-Mtr-058327 Medicago truncatula 41.52 4.00e-39 156.00
IUUC-Mga-059943 Meleagris gallopavo 93.20 0.00e+00 5649.00
IUUC-Mmr-061178 Microcebus murinus 77.22 0.00e+00 3664.00
IUUC-Mdo-063031 Monodelphis domestica 81.24 0.00e+00 3713.00
IUUC-Mmu-063650 Mus musculus 77.70 0.00e+00 3492.00
IUUC-Mac-064935 Musa acuminata 33.50 9.00e-28 118.00
IUUC-Mpu-066495 Mustela putorius furo 80.66 0.00e+00 3401.00
IUUC-Mlu-068045 Myotis lucifugus 74.18 0.00e+00 4565.00
IUUC-Nle-069064 Nomascus leucogenys 79.50 0.00e+00 4969.00
IUUC-Opr-071043 Ochotona princeps 73.78 0.00e+00 3057.00
IUUC-Ont-072556 Oreochromis niloticus 64.69 0.00e+00 1130.00
IUUC-Oan-073324 Ornithorhynchus anatinus 76.35 0.00e+00 2123.00
IUUC-Ocu-074190 Oryctolagus cuniculus 78.06 0.00e+00 4888.00
IUUC-Oba-075647 Oryza barthii 49.36 8.00e-39 155.00
IUUC-Obr-076458 Oryza brachyantha 33.00 2.00e-25 110.00
IUUC-Ogl-077851 Oryza glaberrima 31.74 1.00e-24 107.00
IUUC-Ogu-078706 Oryza glumaepatula 32.18 3.00e-25 110.00
IUUC-Oin-079802 Oryza indica 29.47 1.00e-19 91.30
IUUC-Olo-080577 Oryza longistaminata 47.71 3.00e-36 147.00
IUUC-Ome-081214 Oryza meridionalis 49.36 9.00e-39 155.00
IUUC-Oni-083000 Oryza nivara 49.36 8.00e-39 155.00
IUUC-Opu-083842 Oryza punctata 49.36 8.00e-39 155.00
IUUC-Oru-084361 Oryza rufipogon 49.36 9.00e-39 155.00
IUUC-Osa-085421 Oryza sativa 32.49 3.00e-24 106.00
IUUC-Ola-086609 Oryzias latipes 46.54 0.00e+00 747.00
IUUC-Olu-087718 Ostreococcus lucimarinus 37.50 5.00e-36 147.00
IUUC-Oga-088208 Otolemur garnettii 78.89 0.00e+00 4884.00
IUUC-Oar-090152 Ovis aries 79.26 0.00e+00 5011.00
IUUC-Ptr-091127 Pan troglodytes 79.36 0.00e+00 4895.00
IUUC-Pan-092679 Papio anubis 79.20 0.00e+00 3999.00
IUUC-Psi-094059 Pelodiscus sinensis 86.54 0.00e+00 5514.00
IUUC-Pma-094258 Petromyzon marinus 59.53 0.00e+00 677.00
IUUC-Ppa-095221 Physcomitrella patens 33.66 3.00e-27 116.00
IUUC-Pfo-096536 Poecilia formosa 68.25 0.00e+00 1128.00
IUUC-Pab-098262 Pongo abelii 79.66 0.00e+00 4966.00
IUUC-Pop-099585 Populus trichocarpa 31.63 8.00e-25 108.00
IUUC-Pca-100358 Procavia capensis 75.86 0.00e+00 4601.00
IUUC-Ppe-101920 Prunus persica 34.64 1.00e-25 112.00
IUUC-Pva-102522 Pteropus vampyrus 74.55 0.00e+00 3899.00
IUUC-Rno-105200 Rattus norvegicus 77.33 0.00e+00 3448.00
IUUC-Sha-107174 Sarcophilus harrisii 81.33 0.00e+00 5020.00
IUUC-Smo-109164 Selaginella moellendorffii 51.30 7.00e-41 162.00
IUUC-Sit-110552 Setaria italica 32.19 3.00e-26 113.00
IUUC-Sly-111176 Solanum lycopersicum 48.37 1.00e-36 148.00
IUUC-Stu-112529 Solanum tuberosum 48.37 8.00e-39 155.00
IUUC-Sar-113503 Sorex araneus 71.35 0.00e+00 2615.00
IUUC-Sbi-114254 Sorghum bicolor 26.92 4.00e-10 59.70
IUUC-Ssc-115509 Sus scrofa 51.17 0.00e+00 755.00
IUUC-Tgu-117047 Taeniopygia guttata 91.59 0.00e+00 5845.00
IUUC-Tru-118328 Takifugu rubripes 65.99 0.00e+00 1152.00
IUUC-Tsy-118953 Tarsius syrichta 71.39 0.00e+00 2360.00
IUUC-Tni-120837 Tetraodon nigroviridis 66.54 0.00e+00 1139.00
IUUC-Tca-121624 Theobroma cacao 32.99 1.00e-25 111.00
IUUC-Tae-124647 Triticum aestivum 29.72 9.00e-19 88.20
IUUC-Tbe-127950 Tupaia belangeri 71.58 0.00e+00 2220.00
IUUC-Ttr-128643 Tursiops truncatus 77.96 0.00e+00 4744.00
IUUC-Vpa-130660 Vicugna pacos 80.35 0.00e+00 1811.00
IUUC-Vvi-131476 Vitis vinifera 46.75 5.00e-40 159.00
IUUC-Xtr-132869 Xenopus tropicalis 60.28 0.00e+00 3673.00
IUUC-Xma-133393 Xiphophorus maculatus 64.78 0.00e+00 1081.00
Created Date 25-Jun-2017

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