iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012438

UUCD1 version

UUC-BoT-00049

Ensembl Protein ID

ENSBTAP00000004896.5

UniProt Accession

A5PJS1; F1MUX3; A5PJS1_BOVIN

Genbank Protein ID

AAI42219.1

Protein Name

GNB5 protein

Genbank Nucleotide ID

DAAA02028995

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000003762.5	ENSBTAT00000004896.5	ENSBTAP00000004896.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.40e-43	142.5	193	233
UBD/Beta-Prp	1.00e-54	185.9	147	352

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllk 37
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++
   Q: 193  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCVQ 233
           8***********9644499********************98 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++  
   Q: 147  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCVQ-A 234
           567889999*********99***************************************9778************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 235  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 323
           ******************************************95333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++r+W
   Q: 324  HENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
           ***************************** PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MAADGLHENE TLASLKSEAE SLKGKLEEER AKLHDVELHQ VAERVEALGQ FVMKTRRTLK 60
GHGNKVLCMD WCKDKRRLVS SSQDGKVIVW DSFTTNKEHA VTMPCTWVMA CAYAPSGCAI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCCCCGCTT CCCTCCCGCC GCGTCCCCGC GCGAAGATGG CAGCCGACGG GCTGCATGAG 60
AACGAGACGC TGGCGTCGCT CAAGAGCGAG GCCGAGAGCC TCAAGGGCAA ACTGGAGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005096--F:GTPase activator activity
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:1901386--P:negative regulation of voltage-gated calcium channel activity

KEGG

bta:535365

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	91.78	0.00e+00	678.00
IUUC-Apl-003399	Anas platyrhynchos	98.40	0.00e+00	650.00
IUUC-Aca-004861	Anolis carolinensis	96.60	0.00e+00	718.00
IUUC-Ame-011851	Astyanax mexicanus	92.02	0.00e+00	687.00
IUUC-Cel-018408	Caenorhabditis elegans	64.64	3.00e-139	488.00
IUUC-Cja-019086	Callithrix jacchus	99.15	0.00e+00	726.00
IUUC-Cfa-021255	Canis familiaris	99.13	0.00e+00	675.00
IUUC-Cpo-021398	Cavia porcellus	97.46	0.00e+00	717.00
IUUC-Csa-023776	Chlorocebus sabaeus	98.87	0.00e+00	728.00
IUUC-Cin-025305	Ciona intestinalis	57.65	2.00e-131	461.00
IUUC-Csv-026058	Ciona savignyi	57.81	1.00e-127	449.00
IUUC-Dre-028572	Danio rerio	92.15	0.00e+00	679.00
IUUC-Dno-029958	Dasypus novemcinctus	85.08	3.00e-121	427.00
IUUC-Dor-031013	Dipodomys ordii	99.22	2.00e-153	534.00
IUUC-Dme-031889	Drosophila melanogaster	68.31	1.00e-148	519.00
IUUC-Eca-033977	Equus caballus	94.00	0.00e+00	684.00
IUUC-Eeu-035079	Erinaceus europaeus	98.58	0.00e+00	729.00
IUUC-Fca-035693	Felis catus	92.31	0.00e+00	674.00
IUUC-Fal-037345	Ficedula albicollis	97.73	0.00e+00	724.00
IUUC-Gmo-039222	Gadus morhua	90.65	0.00e+00	657.00
IUUC-Gga-040320	Gallus gallus	97.73	0.00e+00	726.00
IUUC-Gac-042644	Gasterosteus aculeatus	90.93	0.00e+00	686.00
IUUC-Ggo-044489	Gorilla gorilla	94.63	0.00e+00	687.00
IUUC-Hsa-046434	Homo sapiens	99.15	0.00e+00	731.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	93.35	9.00e-177	612.00
IUUC-Loc-052790	Lepisosteus oculatus	94.57	0.00e+00	671.00
IUUC-Laf-054255	Loxodonta africana	98.29	0.00e+00	718.00
IUUC-Mcc-055610	Macaca mulatta	98.86	0.00e+00	724.00
IUUC-Meu-056819	Macropus eugenii	96.47	0.00e+00	626.00
IUUC-Mga-059740	Meleagris gallopavo	92.71	0.00e+00	664.00
IUUC-Mmr-061221	Microcebus murinus	98.87	0.00e+00	729.00
IUUC-Mdo-062619	Monodelphis domestica	98.02	0.00e+00	725.00
IUUC-Mmu-064266	Mus musculus	99.15	0.00e+00	731.00
IUUC-Mpu-065766	Mustela putorius furo	99.00	0.00e+00	627.00
IUUC-Mlu-067221	Myotis lucifugus	90.65	0.00e+00	667.00
IUUC-Nle-069515	Nomascus leucogenys	99.37	0.00e+00	660.00
IUUC-Opr-070195	Ochotona princeps	89.52	0.00e+00	642.00
IUUC-Ont-071535	Oreochromis niloticus	82.72	7.00e-159	553.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.84	2.00e-107	380.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.34	0.00e+00	629.00
IUUC-Ola-086578	Oryzias latipes	92.05	0.00e+00	650.00
IUUC-Oga-089090	Otolemur garnettii	98.59	0.00e+00	725.00
IUUC-Oar-090017	Ovis aries	94.00	0.00e+00	668.00
IUUC-Ptr-091280	Pan troglodytes	99.37	0.00e+00	662.00
IUUC-Pan-092198	Papio anubis	98.74	0.00e+00	660.00
IUUC-Psi-093030	Pelodiscus sinensis	90.54	0.00e+00	665.00
IUUC-Pma-094140	Petromyzon marinus	89.47	1.00e-89	321.00
IUUC-Pfo-097182	Poecilia formosa	91.78	0.00e+00	664.00
IUUC-Pab-098157	Pongo abelii	99.15	0.00e+00	733.00
IUUC-Pca-100988	Procavia capensis	75.07	6.00e-145	506.00
IUUC-Pva-102232	Pteropus vampyrus	86.57	4.00e-177	613.00
IUUC-Rno-105526	Rattus norvegicus	95.49	0.00e+00	695.00
IUUC-Sha-106754	Sarcophilus harrisii	98.58	0.00e+00	682.00
IUUC-Ssc-115390	Sus scrofa	98.87	0.00e+00	727.00
IUUC-Tgu-117377	Taeniopygia guttata	98.10	0.00e+00	652.00
IUUC-Tru-117938	Takifugu rubripes	91.78	0.00e+00	652.00
IUUC-Tsy-119392	Tarsius syrichta	83.57	3.00e-168	584.00
IUUC-Tni-119834	Tetraodon nigroviridis	76.49	4.00e-153	534.00
IUUC-Tbe-127469	Tupaia belangeri	97.14	0.00e+00	692.00
IUUC-Ttr-128252	Tursiops truncatus	98.58	0.00e+00	720.00
IUUC-Vpa-130173	Vicugna pacos	91.02	1.00e-137	482.00
IUUC-Xtr-131803	Xenopus tropicalis	96.03	0.00e+00	676.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence