iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115332

Ensembl Protein ID

ENSSSCP00000027280.1

UniProt Accession

I3LT36; I3LT36_PIG

Genbank Protein ID

ENSSSCP00000027280

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

FP102369

Gene Name

MAP3K10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000028036.1	ENSSSCT00000022919.1	ENSSSCP00000027280.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-14	54.4	22	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvieke...eqdegWlkgvkelegkrGlfPenFve 60
            + +dyea+ d+eLtl++Gd v+v++++   + degW+ g+   +g+ G+fP+n+v+
   Q: 22   TAVFDYEAAGDEELTLRRGDRVQVLSQDcavSGDEGWWTGQ-LPSGRVGVFPSNYVA 77
           589**********************77622257*******7.99***********96 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MEEEEGGAAK EWGTTPAGPV WTAVFDYEAA GDEELTLRRG DRVQVLSQDC AVSGDEGWWT 60
GQLPSGRVGV FPSNYVAPGT PAAPAGLRLP QEIPFHELQL EEIIGVGGFG KVYRALWRGE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCACTCAGG CACCGCCGGC GGCCCCGGGA AGTGGCGCGG GCGGGGGCAG GGGCTGGGGC 60
CGACCCGGAG GCCGGTGCTG AGGATGGTGG CCGCCAGGCT GCCCCGTGCG TGAGGAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR015785--MAP3K10
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004706--F:JUN kinase kinase kinase activity
GO:0003714--F:transcription corepressor activity
GO:0007257--P:activation of JUN kinase activity
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001187	Ailuropoda melanoleuca	93.87	0.00e+00	961.00
IUUC-Atr-002478	Amborella trichopoda	33.33	4.00e-24	106.00
IUUC-Aca-004768	Anolis carolinensis	76.92	0.00e+00	803.00
IUUC-Aly-006459	Arabidopsis lyrata	32.74	2.00e-28	120.00
IUUC-Ath-006581	Arabidopsis thaliana	32.38	9.00e-28	118.00
IUUC-Bta-013545	Bos taurus	99.14	0.00e+00	856.00
IUUC-Bdi-014449	Brachypodium distachyon	32.36	2.00e-25	110.00
IUUC-Bol-016287	Brassica oleracea	31.67	2.00e-27	117.00
IUUC-Bra-016997	Brassica rapa	32.97	2.00e-27	118.00
IUUC-Cja-019696	Callithrix jacchus	95.02	0.00e+00	952.00
IUUC-Cpo-021993	Cavia porcellus	92.18	0.00e+00	990.00
IUUC-Cre-022669	Chlamydomonas reinhardtii	33.64	7.00e-20	91.30
IUUC-Csa-024243	Chlorocebus sabaeus	95.36	0.00e+00	962.00
IUUC-Cho-024961	Choloepus hoffmanni	93.81	4.00e-115	408.00
IUUC-Csv-026102	Ciona savignyi	57.05	8.00e-153	533.00
IUUC-Dre-028573	Danio rerio	72.14	0.00e+00	771.00
IUUC-Dno-029095	Dasypus novemcinctus	93.81	0.00e+00	931.00
IUUC-Dor-030866	Dipodomys ordii	66.01	6.00e-167	581.00
IUUC-Dme-032210	Drosophila melanogaster	49.58	2.00e-141	496.00
IUUC-Eca-033782	Equus caballus	70.31	4.00e-113	402.00
IUUC-Fca-036250	Felis catus	88.71	0.00e+00	983.00
IUUC-Fal-036753	Ficedula albicollis	67.49	0.00e+00	734.00
IUUC-Gmo-038497	Gadus morhua	71.69	0.00e+00	772.00
IUUC-Gac-042509	Gasterosteus aculeatus	70.68	0.00e+00	747.00
IUUC-Gma-043336	Glycine max	29.90	5.00e-26	113.00
IUUC-Ggo-045471	Gorilla gorilla	90.44	0.00e+00	890.00
IUUC-Hsa-046936	Homo sapiens	95.69	0.00e+00	936.00
IUUC-Hvu-047798	Hordeum vulgare	32.27	3.00e-24	106.00
IUUC-Itr-048231	Ictidomys tridecemlineatus	91.29	0.00e+00	988.00
IUUC-Lch-049935	Latimeria chalumnae	74.22	0.00e+00	785.00
IUUC-Loc-052286	Lepisosteus oculatus	67.86	0.00e+00	755.00
IUUC-Laf-053926	Loxodonta africana	65.30	0.00e+00	746.00
IUUC-Mcc-055733	Macaca mulatta	90.79	0.00e+00	959.00
IUUC-Meu-056762	Macropus eugenii	69.71	6.00e-159	554.00
IUUC-Mtr-058733	Medicago truncatula	32.22	2.00e-26	114.00
IUUC-Mmr-061210	Microcebus murinus	62.40	0.00e+00	736.00
IUUC-Mdo-062516	Monodelphis domestica	82.87	0.00e+00	885.00
IUUC-Mmu-064082	Mus musculus	95.00	0.00e+00	991.00
IUUC-Mac-065156	Musa acuminata	31.93	8.00e-28	119.00
IUUC-Mpu-065934	Mustela putorius furo	96.19	0.00e+00	979.00
IUUC-Mlu-068137	Myotis lucifugus	84.21	0.00e+00	912.00
IUUC-Nle-068969	Nomascus leucogenys	63.88	0.00e+00	732.00
IUUC-Opr-070869	Ochotona princeps	75.53	0.00e+00	792.00
IUUC-Ont-072492	Oreochromis niloticus	71.90	0.00e+00	785.00
IUUC-Ocu-074350	Oryctolagus cuniculus	95.07	0.00e+00	944.00
IUUC-Oba-075616	Oryza barthii	34.88	7.00e-25	108.00
IUUC-Obr-076215	Oryza brachyantha	34.91	5.00e-26	112.00
IUUC-Ogl-077159	Oryza glaberrima	34.88	6.00e-25	109.00
IUUC-Ogu-078228	Oryza glumaepatula	35.35	2.00e-25	110.00
IUUC-Oin-079079	Oryza indica	34.93	2.00e-25	110.00
IUUC-Olo-080309	Oryza longistaminata	35.07	2.00e-24	107.00
IUUC-Oni-082428	Oryza nivara	34.88	7.00e-25	108.00
IUUC-Opu-083527	Oryza punctata	35.35	5.00e-25	109.00
IUUC-Oru-084678	Oryza rufipogon	34.93	2.00e-25	110.00
IUUC-Osa-086117	Oryza sativa	34.93	2.00e-25	110.00
IUUC-Ola-087224	Oryzias latipes	71.45	0.00e+00	783.00
IUUC-Oga-088351	Otolemur garnettii	95.02	0.00e+00	1014.00
IUUC-Oar-089467	Ovis aries	66.40	3.00e-169	588.00
IUUC-Ptr-091607	Pan troglodytes	95.69	0.00e+00	937.00
IUUC-Pan-092403	Papio anubis	95.20	0.00e+00	932.00
IUUC-Pfo-096104	Poecilia formosa	68.85	0.00e+00	751.00
IUUC-Pab-098396	Pongo abelii	95.69	0.00e+00	937.00
IUUC-Pop-099554	Populus trichocarpa	29.59	4.00e-24	106.00
IUUC-Pca-100945	Procavia capensis	57.50	8.00e-179	620.00
IUUC-Ppe-101208	Prunus persica	34.55	3.00e-26	114.00
IUUC-Pva-103086	Pteropus vampyrus	96.91	0.00e+00	647.00
IUUC-Rno-105688	Rattus norvegicus	95.00	0.00e+00	993.00
IUUC-Sha-107470	Sarcophilus harrisii	59.49	1.00e-154	540.00
IUUC-Smo-109113	Selaginella moellendorffii	32.72	1.00e-25	110.00
IUUC-Sit-110427	Setaria italica	34.58	4.00e-25	109.00
IUUC-Sly-111849	Solanum lycopersicum	35.09	8.00e-26	112.00
IUUC-Stu-112224	Solanum tuberosum	35.09	1.00e-25	111.00
IUUC-Sbi-113963	Sorghum bicolor	35.05	9.00e-26	112.00
IUUC-Tru-117692	Takifugu rubripes	69.56	0.00e+00	779.00
IUUC-Tsy-119412	Tarsius syrichta	93.38	2.00e-71	263.00
IUUC-Tni-120689	Tetraodon nigroviridis	68.52	0.00e+00	766.00
IUUC-Tca-121565	Theobroma cacao	35.38	4.00e-26	113.00
IUUC-Tae-124203	Triticum aestivum	30.99	5.00e-25	108.00
IUUC-Tur-126322	Triticum urartu	32.26	4.00e-25	109.00
IUUC-Tbe-127643	Tupaia belangeri	98.25	0.00e+00	668.00
IUUC-Ttr-128550	Tursiops truncatus	97.84	0.00e+00	1029.00
IUUC-Vvi-131372	Vitis vinifera	32.26	5.00e-23	102.00
IUUC-Xtr-132108	Xenopus tropicalis	73.93	0.00e+00	807.00
IUUC-Xma-134254	Xiphophorus maculatus	69.18	0.00e+00	770.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence