iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107124

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01151310

Gene Name

TRIM13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000001829.1	ENSSHAT00000002080.1	ENSSHAP00000002057.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.20e-08	35.5	11	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw....pglknssskefrCPlCr 46
           C+iC++ f+d p+vlpC H f+++Cl+ +    +  +   +  f+CP+Cr
   Q: 11   CPICCSLFDD-PRVLPCSHNFCKKCLEGIlegnVRNMLWRQSPFKCPTCR 59
           ********99.**************977777777888889*********8 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MMELLEEDLT CPICCSLFDD PRVLPCSHNF CKKCLEGILE GNVRNMLWRQ SPFKCPTCRK 60
ETSATGVNSL QVNYSLKGIV EKYNKIKVSP KMPVCKGHVG QPLNIFCLTD MQLICGICAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGGAGC TGCTGGAGGA AGACCTCACA TGCCCTATTT GTTGCAGCTT GTTTGATGAT 60
CCCCGGGTTT TGCCCTGCTC TCACAATTTC TGCAAAAAAT GCCTGGAAGG TATCTTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0097038--C:perinuclear endoplasmic reticulum
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010942--P:positive regulation of cell death
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016239--P:positive regulation of macroautophagy
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051865--P:protein autoubiquitination
GO:0010332--P:response to gamma radiation
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

shr:100920821

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002269	Ailuropoda melanoleuca	85.33	0.00e+00	691.00
IUUC-Apl-004168	Anas platyrhynchos	75.98	0.00e+00	641.00
IUUC-Aca-004395	Anolis carolinensis	71.08	2.00e-172	598.00
IUUC-Ame-011325	Astyanax mexicanus	47.06	6.00e-69	254.00
IUUC-Bta-012613	Bos taurus	84.31	0.00e+00	677.00
IUUC-Cja-018856	Callithrix jacchus	83.37	0.00e+00	708.00
IUUC-Cfa-021019	Canis familiaris	84.60	0.00e+00	682.00
IUUC-Cpo-021845	Cavia porcellus	82.11	0.00e+00	666.00
IUUC-Csa-023380	Chlorocebus sabaeus	83.82	0.00e+00	676.00
IUUC-Cho-024733	Choloepus hoffmanni	72.40	2.00e-79	289.00
IUUC-Dre-028675	Danio rerio	61.20	1.00e-110	392.00
IUUC-Dno-030018	Dasypus novemcinctus	83.58	0.00e+00	687.00
IUUC-Dor-030599	Dipodomys ordii	77.24	4.00e-111	393.00
IUUC-Ete-033134	Echinops telfairi	83.62	0.00e+00	698.00
IUUC-Eca-033931	Equus caballus	84.84	0.00e+00	678.00
IUUC-Eeu-034903	Erinaceus europaeus	82.15	0.00e+00	663.00
IUUC-Fca-035642	Felis catus	84.80	0.00e+00	674.00
IUUC-Fal-037108	Ficedula albicollis	75.98	0.00e+00	643.00
IUUC-Gga-040903	Gallus gallus	75.75	0.00e+00	632.00
IUUC-Ggo-044635	Gorilla gorilla	83.86	0.00e+00	680.00
IUUC-Hsa-046345	Homo sapiens	83.86	0.00e+00	682.00
IUUC-Itr-048220	Ictidomys tridecemlineatus	82.00	0.00e+00	649.00
IUUC-Lch-050599	Latimeria chalumnae	60.74	2.00e-141	495.00
IUUC-Loc-052378	Lepisosteus oculatus	63.49	2.00e-117	414.00
IUUC-Laf-053332	Loxodonta africana	85.78	0.00e+00	696.00
IUUC-Mcc-054705	Macaca mulatta	83.86	0.00e+00	674.00
IUUC-Meu-056825	Macropus eugenii	95.84	0.00e+00	785.00
IUUC-Mga-059528	Meleagris gallopavo	75.00	0.00e+00	641.00
IUUC-Mmr-060688	Microcebus murinus	83.86	0.00e+00	675.00
IUUC-Mdo-061882	Monodelphis domestica	94.38	0.00e+00	786.00
IUUC-Mmu-064352	Mus musculus	80.64	0.00e+00	681.00
IUUC-Mpu-066712	Mustela putorius furo	83.25	0.00e+00	637.00
IUUC-Mlu-068093	Myotis lucifugus	83.58	0.00e+00	667.00
IUUC-Nle-069310	Nomascus leucogenys	83.82	0.00e+00	675.00
IUUC-Ont-071759	Oreochromis niloticus	60.19	9.00e-112	396.00
IUUC-Oan-073673	Ornithorhynchus anatinus	83.13	0.00e+00	709.00
IUUC-Ocu-074192	Oryctolagus cuniculus	84.11	0.00e+00	684.00
IUUC-Ola-087424	Oryzias latipes	58.99	2.00e-111	395.00
IUUC-Oga-088808	Otolemur garnettii	84.56	0.00e+00	678.00
IUUC-Oar-089553	Ovis aries	83.62	0.00e+00	675.00
IUUC-Ptr-090518	Pan troglodytes	83.62	0.00e+00	676.00
IUUC-Pan-092781	Papio anubis	83.86	0.00e+00	674.00
IUUC-Psi-093914	Pelodiscus sinensis	75.06	0.00e+00	639.00
IUUC-Pma-094162	Petromyzon marinus	36.73	6.00e-44	171.00
IUUC-Pfo-096346	Poecilia formosa	57.89	7.00e-110	390.00
IUUC-Pca-100914	Procavia capensis	82.89	0.00e+00	700.00
IUUC-Pva-102728	Pteropus vampyrus	84.35	0.00e+00	676.00
IUUC-Rno-105922	Rattus norvegicus	80.64	0.00e+00	634.00
IUUC-Sja-107830	Schizosaccharomyces japonicus	36.05	5.00e-08	52.00
IUUC-Sar-113607	Sorex araneus	81.42	0.00e+00	640.00
IUUC-Ssc-116355	Sus scrofa	84.80	0.00e+00	681.00
IUUC-Tgu-116476	Taeniopygia guttata	75.49	0.00e+00	639.00
IUUC-Tru-118737	Takifugu rubripes	59.03	2.00e-110	392.00
IUUC-Tsy-118908	Tarsius syrichta	83.62	0.00e+00	684.00
IUUC-Tni-119737	Tetraodon nigroviridis	33.55	7.00e-49	187.00
IUUC-Tbe-127258	Tupaia belangeri	85.09	0.00e+00	686.00
IUUC-Ttr-128921	Tursiops truncatus	33.54	6.00e-52	197.00
IUUC-Vpa-130138	Vicugna pacos	83.86	0.00e+00	677.00
IUUC-Xtr-132100	Xenopus tropicalis	59.56	2.00e-137	482.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence