iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003698

Ensembl Protein ID

ENSAPLP00000010283.1

UniProt Accession

U3ISR0; U3ISR0_ANAPL

Genbank Protein ID

ENSAPLP00000010283

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01126797

Gene Name

ARHGEF38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000010561.1	ENSAPLT00000010994.1	ENSAPLP00000010283.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.90e-11	42.9	609	664

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFv 59
            ++ + y ++a nd eL+l++  +v+++  ++ + +++W+ +  e++g++G +P+n+ 
   Q: 609  STFYAVYAFQARNDQELSLEEYQKVRILrfSDLSGNKEWWLA--EAKGQKGYVPSNYL 664
           678899**********************************99..9***********96 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

KMAPQSGSSS PAALPQEDEE ATRRMMAKRV KIIAELMQTE RDYISDLDLC IKEVIQPLRN 60
KQIVHFDVDG LFSNIESVHQ ISAKLLSLLE EATTDVEPPM QVIGEVFLQI KGPLEDTYKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCCCACAG CCGGCACAAG CTGTACATGG GGGAGAGGAG GAGGACGGAG CCCGTGGTGG 60
AGAGCAGCGC GGCCGGGGAG CACGGCGCCC TGCGAAGGAG TCAGTCCGAC CGGAGCGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS50002--SH3

Pfam

PF00621--RhoGEF
PF07653--SH3_2
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004844	Anolis carolinensis	59.97	0.00e+00	666.00
IUUC-Gmo-038829	Gadus morhua	46.33	1.00e-122	433.00
IUUC-Gga-040892	Gallus gallus	71.93	0.00e+00	973.00
IUUC-Ggo-044900	Gorilla gorilla	32.34	2.00e-82	299.00
IUUC-Lch-050096	Latimeria chalumnae	30.73	1.00e-82	300.00
IUUC-Mga-060170	Meleagris gallopavo	74.95	0.00e+00	714.00
IUUC-Ptr-090508	Pan troglodytes	32.05	7.00e-82	298.00
IUUC-Tru-118483	Takifugu rubripes	50.28	1.00e-128	452.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence