iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	miRNAMap	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.20e-06	28.5	134	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkw...........pglknssskefr...............CPlCr 46
           C iCl+ f  k+    +pC H fh +Cl ++                      +               CP+Cr
   Q: 134  CVICLYGFqeKEAFTKTPCYHYFHCHCLARYiqhmeqelntqE----------QeqqhvvtkqkavgvqCPVCR 197
           ********65333556************999766554433330..........2334566666667777****8 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAASASTAAG EEDWVLPSEV EVLESIYLDE LQVMKGNGRS PWEIFITLHP ATAEVQDSQF 60
VCFTLVLQVP VQYPHEVPQI SIRNPRGLSD EQIHKISQAL GHVAKEGLGT AMLYELIEKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAAGACAT GGCGGCGTCT GCGTCTACAG CTGCCGGGGA AGAGGACTGG TAACTTTGGG 60
TCATAGGTTT TGGCTGGCTG CCTGGATCTG GTGCTGGGAG CTAGCAACAG CTTCGGACCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50908--RWD
PS50089--ZF_RING_2

Pfam

PF05773--RWD

SMART

SM00184--RING
SM00591--RWD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity

KEGG

rno:301515

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001954	Ailuropoda melanoleuca	81.92	0.00e+00	657.00
IUUC-Atr-002830	Amborella trichopoda	24.59	1.00e-14	73.90
IUUC-Apl-003293	Anas platyrhynchos	68.77	2.00e-92	332.00
IUUC-Aca-005092	Anolis carolinensis	70.15	5.00e-101	361.00
IUUC-Aly-005434	Arabidopsis lyrata	28.96	5.00e-20	91.70
IUUC-Ath-006770	Arabidopsis thaliana	29.63	3.00e-19	89.00
IUUC-Ame-011754	Astyanax mexicanus	49.62	5.00e-59	221.00
IUUC-Bta-012592	Bos taurus	77.73	0.00e+00	652.00
IUUC-Bdi-015061	Brachypodium distachyon	27.71	2.00e-16	79.70
IUUC-Bol-015743	Brassica oleracea	31.62	6.00e-19	88.20
IUUC-Bra-018072	Brassica rapa	29.82	2.00e-15	76.60
IUUC-Cel-018515	Caenorhabditis elegans	24.03	6.00e-07	47.80
IUUC-Cja-018930	Callithrix jacchus	84.68	0.00e+00	719.00
IUUC-Cfa-020156	Canis familiaris	82.14	0.00e+00	694.00
IUUC-Cpo-021290	Cavia porcellus	78.23	0.00e+00	687.00
IUUC-Csa-023214	Chlorocebus sabaeus	84.53	0.00e+00	714.00
IUUC-Cin-025416	Ciona intestinalis	31.79	6.00e-42	164.00
IUUC-Csv-026360	Ciona savignyi	34.97	6.00e-42	164.00
IUUC-Dre-028670	Danio rerio	48.50	1.00e-55	210.00
IUUC-Dno-029970	Dasypus novemcinctus	80.17	0.00e+00	694.00
IUUC-Dor-030152	Dipodomys ordii	81.46	0.00e+00	665.00
IUUC-Dme-031914	Drosophila melanogaster	35.54	1.00e-38	153.00
IUUC-Ete-033105	Echinops telfairi	71.99	2.00e-146	512.00
IUUC-Eca-033800	Equus caballus	81.26	0.00e+00	652.00
IUUC-Eeu-034525	Erinaceus europaeus	61.88	4.00e-115	408.00
IUUC-Fca-035644	Felis catus	83.37	0.00e+00	729.00
IUUC-Fal-037121	Ficedula albicollis	68.20	5.00e-102	364.00
IUUC-Gmo-039444	Gadus morhua	50.80	3.00e-58	219.00
IUUC-Gga-041221	Gallus gallus	44.77	1.00e-73	270.00
IUUC-Gac-042354	Gasterosteus aculeatus	47.25	7.00e-69	254.00
IUUC-Gma-043721	Glycine max	29.94	2.00e-15	77.40
IUUC-Ggo-044879	Gorilla gorilla	84.53	0.00e+00	726.00
IUUC-Hsa-045739	Homo sapiens	84.31	0.00e+00	725.00
IUUC-Itr-047915	Ictidomys tridecemlineatus	85.40	0.00e+00	686.00
IUUC-Lch-050277	Latimeria chalumnae	55.29	1.00e-66	246.00
IUUC-Lpe-051139	Leersia perrieri	28.57	2.00e-17	83.20
IUUC-Loc-052367	Lepisosteus oculatus	56.96	2.00e-19	86.30
IUUC-Laf-053559	Loxodonta africana	75.93	0.00e+00	686.00
IUUC-Mcc-055367	Macaca mulatta	76.47	0.00e+00	657.00
IUUC-Meu-056730	Macropus eugenii	67.04	1.00e-135	476.00
IUUC-Mtr-058418	Medicago truncatula	25.72	6.00e-15	75.10
IUUC-Mga-060090	Meleagris gallopavo	67.05	9.00e-62	230.00
IUUC-Mmr-060618	Microcebus murinus	85.19	0.00e+00	729.00
IUUC-Mdo-063084	Monodelphis domestica	69.20	1.00e-146	512.00
IUUC-Mmu-063854	Mus musculus	95.61	0.00e+00	842.00
IUUC-Mac-064922	Musa acuminata	27.55	8.00e-18	84.30
IUUC-Mpu-066419	Mustela putorius furo	81.48	0.00e+00	672.00
IUUC-Mlu-067289	Myotis lucifugus	78.26	0.00e+00	663.00
IUUC-Nle-069090	Nomascus leucogenys	84.97	0.00e+00	749.00
IUUC-Opr-070601	Ochotona princeps	79.43	0.00e+00	638.00
IUUC-Ont-072434	Oreochromis niloticus	52.92	5.00e-68	251.00
IUUC-Ocu-074855	Oryctolagus cuniculus	81.62	0.00e+00	686.00
IUUC-Oba-075792	Oryza barthii	27.02	3.00e-18	86.30
IUUC-Obr-076917	Oryza brachyantha	27.44	2.00e-18	86.70
IUUC-Ogl-077872	Oryza glaberrima	25.60	1.00e-16	80.90
IUUC-Ogu-078151	Oryza glumaepatula	26.77	5.00e-18	85.50
IUUC-Oin-079465	Oryza indica	26.13	2.00e-18	86.70
IUUC-Olo-080907	Oryza longistaminata	26.32	5.00e-14	72.80
IUUC-Ome-081752	Oryza meridionalis	25.86	1.00e-17	84.30
IUUC-Oni-082420	Oryza nivara	26.80	4.00e-18	85.90
IUUC-Opu-083810	Oryza punctata	28.03	3.00e-19	89.40
IUUC-Oru-085177	Oryza rufipogon	26.33	3.00e-18	85.90
IUUC-Ola-087231	Oryzias latipes	53.69	2.00e-50	191.00
IUUC-Oga-088963	Otolemur garnettii	84.75	0.00e+00	734.00
IUUC-Oar-089292	Ovis aries	78.26	0.00e+00	707.00
IUUC-Ptr-091214	Pan troglodytes	84.97	0.00e+00	731.00
IUUC-Pan-092823	Papio anubis	84.75	0.00e+00	772.00
IUUC-Psi-094084	Pelodiscus sinensis	39.04	3.00e-43	169.00
IUUC-Pfo-096406	Poecilia formosa	49.42	1.00e-61	230.00
IUUC-Pab-098212	Pongo abelii	85.40	0.00e+00	737.00
IUUC-Pop-099369	Populus trichocarpa	25.87	3.00e-15	75.90
IUUC-Pca-100897	Procavia capensis	71.46	1.00e-169	589.00
IUUC-Ppe-101702	Prunus persica	24.51	3.00e-13	69.30
IUUC-Pva-102899	Pteropus vampyrus	79.96	0.00e+00	672.00
IUUC-Sha-107344	Sarcophilus harrisii	67.49	1.00e-137	483.00
IUUC-Smo-109636	Selaginella moellendorffii	25.33	3.00e-09	54.70
IUUC-Sit-109795	Setaria italica	27.82	2.00e-19	89.70
IUUC-Sly-111014	Solanum lycopersicum	26.02	1.00e-16	82.00
IUUC-Stu-112139	Solanum tuberosum	26.02	1.00e-18	87.00
IUUC-Sar-113487	Sorex araneus	87.39	2.00e-50	193.00
IUUC-Sbi-114714	Sorghum bicolor	27.30	2.00e-17	83.20
IUUC-Ssc-115465	Sus scrofa	76.69	0.00e+00	691.00
IUUC-Tgu-117113	Taeniopygia guttata	73.04	2.00e-94	339.00
IUUC-Tsy-119186	Tarsius syrichta	75.00	4.00e-57	215.00
IUUC-Tni-120219	Tetraodon nigroviridis	54.42	4.00e-36	143.00
IUUC-Tca-121748	Theobroma cacao	27.48	5.00e-14	72.00
IUUC-Tae-123014	Triticum aestivum	27.64	1.00e-14	73.90
IUUC-Tbe-127584	Tupaia belangeri	69.59	3.00e-111	395.00
IUUC-Ttr-128244	Tursiops truncatus	80.17	0.00e+00	656.00
IUUC-Vpa-130354	Vicugna pacos	81.12	0.00e+00	691.00
IUUC-Xtr-132402	Xenopus tropicalis	52.17	5.00e-71	261.00
IUUC-Xma-133442	Xiphophorus maculatus	47.50	8.00e-62	231.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence