iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062378

UUCD1 version

UUC-MoD-00678

Ensembl Protein ID

ENSMODP00000013375.3

UniProt Accession

F7CJE2; F7CJE2_MONDO

Protein Name

Uncharacterized protein

Gene Name

ZSWIM2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000010674.3	ENSMODT00000013620.3	ENSMODP00000013375.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.90e-08	34.5	153	208
E3 activity/RING/RING	1.70e-07	31.8	155	207

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek.slveCek.CrewfHpaClklsveeelpnsek..wiCpkCrs 53
           +vC++C+e+  ++k  ++ C++ C + +H +C+k++++ + ++s++  + Cp Cr+
   Q: 153  DVCPICQEELLEKKlPVTYCRHgCGNSVHIKCMKIWADHQDKSSKNsfVKCPLCRE 208
           79*********99999********************6666665555779*****97 PP

E3 activity/RING/RING

   S: 1    CaiCledf......kdgplvlpCgHvfhadClqkw..pglknssskefrCPlCr 46
           C+iC+e++       + ++  +Cg   h +C + w  ++ k+s++ + +CPlCr
   Q: 155  CPICQEELlekklpVT-YCRHGCGNSVHIKCMKIWadHQDKSSKNSFVKCPLCR 207
           ******9976433222.444668888*********9988888888888*****8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MPGGAGGGGG GGGGGGGRGS ERRRLVSDRL KKHQDQALSS HMYLLRETGP TGFLIKEDDP 60
DDCNYRVFLG DPHTCSCSTF MKGNDLCKHI CWVLLKKFKL PRSHEYAFQL GLVEREINEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTGTGCTA AGGGATACCA AAATTAGCAG ACTGACAATC CCTGTACTCA AGGTGTTTAC 60
AATTTAATAG GGGAGACAAA TATATTCAAA GTAAGTTTGT GTATATATAG GAAATAATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR007527--Znf_SWIM
IPR000433--Znf_ZZ

PROSITE

PS50089--ZF_RING_2
PS50966--ZF_SWIM
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF04434--SWIM
PF13639--zf-RING_2
PF00569--ZZ

SMART

SM00184--RING
SM00291--ZnF_ZZ

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0000209--P:protein polyubiquitination

KEGG

mdo:100028146

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001754	Ailuropoda melanoleuca	58.77	0.00e+00	718.00
IUUC-Apl-003359	Anas platyrhynchos	61.24	5.00e-46	176.00
IUUC-Aca-004923	Anolis carolinensis	56.88	6.00e-118	417.00
IUUC-Afl-008716	Aspergillus flavus	32.87	6.00e-17	81.60
IUUC-Ani-009202	Aspergillus nidulans	30.77	2.00e-16	80.10
IUUC-Bta-012456	Bos taurus	56.96	0.00e+00	691.00
IUUC-Cja-019186	Callithrix jacchus	55.48	0.00e+00	657.00
IUUC-Cfa-020604	Canis familiaris	57.00	0.00e+00	646.00
IUUC-Cpo-021774	Cavia porcellus	53.30	0.00e+00	637.00
IUUC-Cre-022861	Chlamydomonas reinhardtii	31.58	4.00e-32	132.00
IUUC-Csa-024126	Chlorocebus sabaeus	58.55	0.00e+00	697.00
IUUC-Cho-024501	Choloepus hoffmanni	66.67	4.00e-141	494.00
IUUC-Cin-025662	Ciona intestinalis	45.07	5.00e-95	341.00
IUUC-Cgl-026506	Colletotrichum gloeosporioides	29.69	3.00e-14	72.40
IUUC-Cne-027076	Cryptococcus neoformans	29.24	2.00e-13	70.50
IUUC-Dre-028700	Danio rerio	46.40	2.00e-114	406.00
IUUC-Dno-030007	Dasypus novemcinctus	56.62	0.00e+00	692.00
IUUC-Dor-030562	Dipodomys ordii	48.77	1.00e-117	417.00
IUUC-Dse-031237	Dothistroma septosporum	29.47	1.00e-12	67.40
IUUC-Ete-032603	Echinops telfairi	63.25	1.00e-126	446.00
IUUC-Eca-033283	Equus caballus	59.72	0.00e+00	719.00
IUUC-Eeu-034619	Erinaceus europaeus	53.16	0.00e+00	645.00
IUUC-Fca-035573	Felis catus	58.23	0.00e+00	722.00
IUUC-Fso-038137	Fusarium solani	28.73	6.00e-13	68.20
IUUC-Ggr-039924	Gaeumannomyces graminis	27.56	1.00e-11	63.90
IUUC-Ggo-045207	Gorilla gorilla	58.06	0.00e+00	696.00
IUUC-Hsa-046776	Homo sapiens	57.10	0.00e+00	686.00
IUUC-Itr-048416	Ictidomys tridecemlineatus	57.82	0.00e+00	704.00
IUUC-Lch-050394	Latimeria chalumnae	45.52	2.00e-145	509.00
IUUC-Loc-052123	Lepisosteus oculatus	40.83	6.00e-135	474.00
IUUC-Lma-053033	Leptosphaeria maculans	31.62	2.00e-13	69.70
IUUC-Laf-053456	Loxodonta africana	57.44	0.00e+00	699.00
IUUC-Mcc-055227	Macaca mulatta	58.23	0.00e+00	692.00
IUUC-Meu-055957	Macropus eugenii	79.54	4.00e-119	421.00
IUUC-Mor-056933	Magnaporthe oryzae	25.95	9.00e-11	60.80
IUUC-Mmr-061710	Microcebus murinus	56.77	0.00e+00	701.00
IUUC-Mmu-064269	Mus musculus	53.55	0.00e+00	651.00
IUUC-Mpu-066736	Mustela putorius furo	56.07	0.00e+00	646.00
IUUC-Mlu-067142	Myotis lucifugus	50.52	2.00e-158	551.00
IUUC-Nfi-068477	Neosartorya fischeri	34.25	2.00e-15	76.60
IUUC-Ncr-068657	Neurospora crassa	32.47	5.00e-13	68.60
IUUC-Nle-069268	Nomascus leucogenys	57.28	0.00e+00	694.00
IUUC-Opr-071154	Ochotona princeps	43.64	1.00e-98	353.00
IUUC-Oan-072878	Ornithorhynchus anatinus	38.69	4.00e-52	198.00
IUUC-Ocu-074017	Oryctolagus cuniculus	56.69	0.00e+00	636.00
IUUC-Oga-088906	Otolemur garnettii	54.11	0.00e+00	647.00
IUUC-Oar-089422	Ovis aries	57.35	0.00e+00	701.00
IUUC-Ptr-090772	Pan troglodytes	56.94	0.00e+00	680.00
IUUC-Pan-092838	Papio anubis	57.90	0.00e+00	673.00
IUUC-Psi-093288	Pelodiscus sinensis	53.16	3.00e-146	511.00
IUUC-Pma-094709	Petromyzon marinus	48.74	4.00e-111	394.00
IUUC-Pfo-096189	Poecilia formosa	42.00	2.00e-94	339.00
IUUC-Pab-098389	Pongo abelii	52.90	2.00e-174	605.00
IUUC-Pca-100376	Procavia capensis	51.52	2.00e-170	592.00
IUUC-Pva-102163	Pteropus vampyrus	55.77	0.00e+00	650.00
IUUC-Pte-104391	Pyrenophora teres	32.63	2.00e-16	79.70
IUUC-Pyt-104706	Pyrenophora triticirepentis	32.03	5.00e-14	71.60
IUUC-Rno-105988	Rattus norvegicus	54.66	0.00e+00	675.00
IUUC-Sha-107063	Sarcophilus harrisii	76.80	0.00e+00	977.00
IUUC-Sar-113069	Sorex araneus	55.43	0.00e+00	649.00
IUUC-Ssc-116112	Sus scrofa	54.75	0.00e+00	629.00
IUUC-Tsy-118825	Tarsius syrichta	60.29	5.00e-177	613.00
IUUC-Tbe-127891	Tupaia belangeri	54.75	0.00e+00	665.00
IUUC-Ttr-129130	Tursiops truncatus	55.20	6.00e-170	590.00
IUUC-Vda-129853	Verticillium dahliae	26.02	3.00e-12	65.90
IUUC-Vpa-130753	Vicugna pacos	55.99	0.00e+00	677.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence