• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046203
UUCD1 version UUC-HoS-00594
Ensembl Protein ID ENSP00000229264.3
UniProt Accession P16520; Q96B71; Q9BQC0; GBB3_HUMAN
Genbank Protein ID AAA52582.1; AAB51313.1; AAC50468.1; CAA72779.1; CAA72779.1; CAA72779.1; CAA72779.1; CAA72779.1; CAA72779.1; CAA72779.1; CAA72779.1; CAA72779.1; AAM15920.1; AAP88802.1; AAT38116.1; AAH00115.1; AAH02454.1; AAH15920.1
Protein Name Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Transducin beta chain 3
Genbank Nucleotide ID M31328; U47924; U47930; Y12050; Y12051; Y12052; Y12053; Y12054; Y12055; Y12056; Y12057; Y12058; AF501884; BT009800; AY631872; BC000115; BC002454; BC015920
Gene Name GNB3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000111664.10 ENST00000229264.7 ENSP00000229264.3
ENSG00000111664.10 ENST00000435982.6 ENSP00000414734.2
ENSG00000111664.10 ENST00000539127.5 ENSP00000444325.1
ENSG00000111664.10 ENST00000537035.1 ENSP00000445967.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbcircBaseCircNetmiRTarBase
microRNATRANSFACmiRWalkTargetScan
RepTarmiRNAMapmiRcodeRAID2
LncRNADisease
Protein-protein Interaction
IIDPINAHINTMentha
InWeb_IM
Disease-associated Variation
ClinVarGWASdbOMIM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMHPRD
BioGRID
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.20e-38 130.2 53 85
UBD/Beta-Prp 1.40e-51 177.1 46 267
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gH ++++++++ +d +llvs+s Dg++ vWD  
   Q: 53   GHLAKIYAMHWaTDsKLLVSASQDGKLIVWDSY 85
           899*********888***************965 PP
   

   UBD/Beta-Prp
   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee... 131
            + r+l gh a+++a+ +  d+k+lv++s+D+ + vwd  t   vh++   ++ v+++++ psg++++ G+ d++  +++l++++   +   
   Q: 46   RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKvsr 137
           55689*****************************************************************************9987777778 PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtd 223
            ls h+g  +c ++ + +n +v++s D+t+ lWd++tg+  + + g ht++  sl+++++ + ++sg++d + klwd+++g+c +t++gh++
   Q: 138  ELSAHTGYLSCCRFLD-DNNIVTSSGDTTCALWDIETGQQKTVFVG-HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
           ***************9.566899**********************9.********************************************* PP
   S: 224  nvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
            ++ + f+pn+e + +gs+D s r++dlr ++ l +++++
   Q: 228  DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHE 267
           *********************************9999984 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     G proteins are composed of 3 units, alpha, beta and gamma. Interacts with RASD2.
 G proteins are composed of 3 units, alpha, beta and gamma. Interacts with RASD2.
Protein Sequence
(Fasta)
MGEMEQLRQE AEQLKKQIAD ARKACADVTL AELVSGLEVV GRVQMRTRRT LRGHLAKIYA 60
MHWATDSKLL VSASQDGKLI VWDSYTTNKV HAIPLRSSWV MTCAYAPSGN FVACGGLDNM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046203|E3,WD_repeat;UBD,Beta-Prp|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGCCTGGAG CCTGTGATTT GTCAGGGAAA TCTCAGCCAC CTGCTCCCCT CATGCAAATG 60
ACCCAAGCCC CTGGCAGCTG CTCCTTAGGC CTCCAAGTGT AAGCCCTGTC TTCCCTCTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046203|E3,WD_repeat;UBD,Beta-Prp|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1014--Congenital stationary night blindness
KW-0903--Direct protein sequencing
KW-0225--Disease mutation
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0807--Transducer
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0044297--C:cell body
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0003924--F:GTPase activity
GO:0051020--F:GTPase binding
GO:0004871--F:signal transducer activity
GO:0071377--P:cellular response to glucagon stimulus
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0006457--P:protein folding
GO:0008217--P:regulation of blood pressure
KEGG hsa:2784
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000161 Aegilops tauschii 49.63 7.00e-76 277.00
IUUC-Aml-002370 Ailuropoda melanoleuca 97.06 0.00e+00 686.00
IUUC-Atr-002610 Amborella trichopoda 49.03 3.00e-86 311.00
IUUC-Apl-004079 Anas platyrhynchos 93.24 0.00e+00 674.00
IUUC-Aca-004539 Anolis carolinensis 90.00 0.00e+00 653.00
IUUC-Aly-006025 Arabidopsis lyrata 50.00 1.00e-83 303.00
IUUC-Ath-006617 Arabidopsis thaliana 50.65 2.00e-83 302.00
IUUC-Bgr-012079 Blumeria graminis 65.38 5.00e-132 464.00
IUUC-Bta-012810 Bos taurus 97.35 0.00e+00 686.00
IUUC-Bci-013621 Botrytis cinerea 66.67 7.00e-132 463.00
IUUC-Bdi-014785 Brachypodium distachyon 49.68 5.00e-87 314.00
IUUC-Bra-016695 Brassica rapa 51.28 2.00e-81 296.00
IUUC-Cja-019894 Callithrix jacchus 99.12 0.00e+00 699.00
IUUC-Cfa-020140 Canis familiaris 96.76 0.00e+00 685.00
IUUC-Cpo-021908 Cavia porcellus 96.76 0.00e+00 685.00
IUUC-Csa-023321 Chlorocebus sabaeus 100.00 0.00e+00 702.00
IUUC-Dno-029783 Dasypus novemcinctus 95.82 1.00e-180 625.00
IUUC-Dse-031388 Dothistroma septosporum 66.67 7.00e-138 483.00
IUUC-Ete-032435 Echinops telfairi 89.71 7.00e-178 616.00
IUUC-Eca-034169 Equus caballus 97.06 0.00e+00 685.00
IUUC-Eeu-034631 Erinaceus europaeus 90.91 9.00e-164 569.00
IUUC-Fca-035392 Felis catus 96.76 0.00e+00 689.00
IUUC-Fal-036902 Ficedula albicollis 91.18 0.00e+00 664.00
IUUC-Gga-040655 Gallus gallus 91.79 0.00e+00 658.00
IUUC-Ggo-045346 Gorilla gorilla 100.00 0.00e+00 702.00
IUUC-Hvu-047596 Hordeum vulgare 49.68 6.00e-86 310.00
IUUC-Itr-048501 Ictidomys tridecemlineatus 96.18 0.00e+00 681.00
IUUC-Lpe-051040 Leersia perrieri 49.36 1.00e-87 316.00
IUUC-Loc-052327 Lepisosteus oculatus 88.24 0.00e+00 642.00
IUUC-Laf-053616 Loxodonta africana 96.47 0.00e+00 684.00
IUUC-Mcc-055798 Macaca mulatta 100.00 0.00e+00 702.00
IUUC-Mga-059516 Meleagris gallopavo 93.24 0.00e+00 673.00
IUUC-Mmr-061701 Microcebus murinus 97.35 0.00e+00 688.00
IUUC-Mdo-061879 Monodelphis domestica 93.82 0.00e+00 671.00
IUUC-Mmu-063132 Mus musculus 97.06 0.00e+00 686.00
IUUC-Mac-064871 Musa acuminata 49.04 4.00e-84 305.00
IUUC-Mpu-066365 Mustela putorius furo 96.76 0.00e+00 687.00
IUUC-Mlu-067628 Myotis lucifugus 96.18 0.00e+00 681.00
IUUC-Ncr-068650 Neurospora crassa 64.62 4.00e-128 451.00
IUUC-Nle-069015 Nomascus leucogenys 98.53 0.00e+00 686.00
IUUC-Opr-070261 Ochotona princeps 97.65 0.00e+00 688.00
IUUC-Ocu-074255 Oryctolagus cuniculus 97.65 0.00e+00 688.00
IUUC-Oba-075818 Oryza barthii 47.69 1.00e-84 306.00
IUUC-Obr-076229 Oryza brachyantha 49.04 4.00e-84 305.00
IUUC-Ogl-077730 Oryza glaberrima 49.68 6.00e-88 317.00
IUUC-Ogu-078583 Oryza glumaepatula 49.23 2.00e-69 255.00
IUUC-Oin-079661 Oryza indica 49.04 4.00e-84 305.00
IUUC-Olo-080225 Oryza longistaminata 49.23 2.00e-69 255.00
IUUC-Oni-082161 Oryza nivara 49.36 1.00e-87 316.00
IUUC-Opu-084072 Oryza punctata 49.68 5.00e-88 318.00
IUUC-Oru-084316 Oryza rufipogon 49.04 4.00e-84 305.00
IUUC-Osa-085380 Oryza sativa 49.04 4.00e-84 305.00
IUUC-Oga-088685 Otolemur garnettii 97.65 0.00e+00 688.00
IUUC-Oar-089373 Ovis aries 94.13 0.00e+00 651.00
IUUC-Ptr-090627 Pan troglodytes 97.35 0.00e+00 682.00
IUUC-Pan-092347 Papio anubis 100.00 0.00e+00 701.00
IUUC-Psi-092965 Pelodiscus sinensis 93.24 0.00e+00 674.00
IUUC-Ppa-095726 Physcomitrella patens 45.05 5.00e-75 275.00
IUUC-Pab-098335 Pongo abelii 99.41 0.00e+00 700.00
IUUC-Pop-099370 Populus trichocarpa 49.35 5.00e-87 314.00
IUUC-Ppe-102016 Prunus persica 47.74 2.00e-84 305.00
IUUC-Pva-102666 Pteropus vampyrus 97.65 0.00e+00 689.00
IUUC-Pte-104053 Pyrenophora teres 65.49 1.00e-136 479.00
IUUC-Rno-105834 Rattus norvegicus 96.47 0.00e+00 649.00
IUUC-Sha-107128 Sarcophilus harrisii 93.82 0.00e+00 668.00
IUUC-Ssl-108539 Sclerotinia sclerotiorum 66.86 1.00e-131 462.00
IUUC-Smo-109652 Selaginella moellendorffii 43.89 2.00e-74 273.00
IUUC-Sit-110441 Setaria italica 49.36 2.00e-87 315.00
IUUC-Sly-111784 Solanum lycopersicum 49.35 2.00e-84 306.00
IUUC-Stu-112400 Solanum tuberosum 49.35 2.00e-84 306.00
IUUC-Sbi-114038 Sorghum bicolor 48.72 4.00e-86 311.00
IUUC-Ssc-115886 Sus scrofa 97.35 0.00e+00 686.00
IUUC-Tgu-116461 Taeniopygia guttata 91.76 0.00e+00 667.00
IUUC-Tca-121224 Theobroma cacao 49.68 7.00e-87 314.00
IUUC-Tae-125653 Triticum aestivum 50.00 4.00e-86 311.00
IUUC-Tur-126755 Triticum urartu 49.52 8.00e-87 315.00
IUUC-Tbe-127694 Tupaia belangeri 80.88 8.00e-148 516.00
IUUC-Vvi-131162 Vitis vinifera 49.68 1.00e-86 313.00
IUUC-Xtr-132928 Xenopus tropicalis 88.24 4.00e-179 620.00
IUUC-Zma-135893 Zea mays 48.72 4.00e-86 311.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved