iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072347

Ensembl Protein ID

ENSONIP00000000590.1

UniProt Accession

I3IVF0; I3IVF0_ORENI

Genbank Protein ID

ENSONIP00000000590

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AERX01047864

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000000464.1	ENSONIT00000000589.1	ENSONIP00000000590.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.10e-14	52.4	5	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            +lydyea ++++L +kkGd+++++   e++++W+++    +g++G +P+n+v+k
   Q: 5    MALYDYEAIHEGDLGFKKGDKLKIL---EESGEWWRAMLISTGQEGYIPSNYVAK 56
           69***********************...99***********************86 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

ESIAMALYDY EAIHEGDLGF KKGDKLKILE ESGEWWRAML ISTGQEGYIP SNYVAKDTLE 60
AEEWFFKGVS RKDAERQLLA PGNKIGSFMI RDSETTKGSY SLSVRDNDPQ SGDTVKHYKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAGTATTG CCATGGCACT GTACGACTAT GAGGCCATTC ACGAGGGAGA CCTTGGCTTC 60
AAGAAGGGAG ATAAGCTGAA AATCTTAGAA GAGTAAGTTC AACCACAAAA AAGATGGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001284	Ailuropoda melanoleuca	82.06	0.00e+00	777.00
IUUC-Apl-003285	Anas platyrhynchos	80.31	0.00e+00	773.00
IUUC-Aca-004724	Anolis carolinensis	81.92	0.00e+00	759.00
IUUC-Ame-011954	Astyanax mexicanus	90.83	0.00e+00	833.00
IUUC-Bta-013060	Bos taurus	82.29	0.00e+00	781.00
IUUC-Cja-019817	Callithrix jacchus	82.06	0.00e+00	783.00
IUUC-Cfa-020511	Canis familiaris	82.06	0.00e+00	781.00
IUUC-Cpo-022538	Cavia porcellus	81.88	0.00e+00	775.00
IUUC-Csa-024143	Chlorocebus sabaeus	82.96	0.00e+00	784.00
IUUC-Dre-028157	Danio rerio	91.95	0.00e+00	874.00
IUUC-Dno-029761	Dasypus novemcinctus	80.80	0.00e+00	778.00
IUUC-Eca-034090	Equus caballus	80.58	0.00e+00	758.00
IUUC-Fca-035937	Felis catus	81.26	0.00e+00	752.00
IUUC-Fal-036624	Ficedula albicollis	80.58	0.00e+00	775.00
IUUC-Gmo-039009	Gadus morhua	87.47	0.00e+00	834.00
IUUC-Gga-040296	Gallus gallus	78.97	0.00e+00	764.00
IUUC-Gac-042362	Gasterosteus aculeatus	93.51	0.00e+00	886.00
IUUC-Ggo-044570	Gorilla gorilla	82.51	0.00e+00	787.00
IUUC-Hsa-046378	Homo sapiens	82.74	0.00e+00	788.00
IUUC-Itr-048695	Ictidomys tridecemlineatus	80.36	0.00e+00	774.00
IUUC-Loc-052904	Lepisosteus oculatus	88.62	0.00e+00	843.00
IUUC-Laf-053654	Loxodonta africana	81.84	0.00e+00	781.00
IUUC-Mcc-055317	Macaca mulatta	83.18	0.00e+00	790.00
IUUC-Mga-060194	Meleagris gallopavo	76.73	0.00e+00	736.00
IUUC-Mmr-061510	Microcebus murinus	81.84	0.00e+00	779.00
IUUC-Mdo-062035	Monodelphis domestica	81.35	0.00e+00	773.00
IUUC-Mmu-064037	Mus musculus	80.58	0.00e+00	778.00
IUUC-Mpu-066874	Mustela putorius furo	82.06	0.00e+00	776.00
IUUC-Mlu-068202	Myotis lucifugus	79.02	0.00e+00	753.00
IUUC-Nle-069222	Nomascus leucogenys	83.18	0.00e+00	789.00
IUUC-Opr-070705	Ochotona princeps	81.17	0.00e+00	774.00
IUUC-Ocu-074490	Oryctolagus cuniculus	81.39	0.00e+00	775.00
IUUC-Ola-086521	Oryzias latipes	92.62	0.00e+00	878.00
IUUC-Oga-088153	Otolemur garnettii	82.59	0.00e+00	788.00
IUUC-Oar-090184	Ovis aries	81.29	0.00e+00	773.00
IUUC-Ptr-090505	Pan troglodytes	78.48	0.00e+00	735.00
IUUC-Pan-092260	Papio anubis	83.18	0.00e+00	790.00
IUUC-Pma-094311	Petromyzon marinus	73.71	0.00e+00	708.00
IUUC-Pfo-096566	Poecilia formosa	93.51	0.00e+00	891.00
IUUC-Pva-103021	Pteropus vampyrus	82.96	0.00e+00	784.00
IUUC-Rno-105309	Rattus norvegicus	81.03	0.00e+00	781.00
IUUC-Sha-107099	Sarcophilus harrisii	80.45	0.00e+00	768.00
IUUC-Tgu-116912	Taeniopygia guttata	81.66	0.00e+00	778.00
IUUC-Tru-118449	Takifugu rubripes	90.77	0.00e+00	844.00
IUUC-Tbe-128144	Tupaia belangeri	73.54	0.00e+00	683.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence