iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089722

Ensembl Protein ID

ENSOARP00000015294.1

UniProt Accession

W5PXW0; W5PXW0_SHEEP

Genbank Protein ID

ENSOARP00000015294

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01078896

Gene Name

NPHP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000014241.1	ENSOART00000015516.1	ENSOARP00000015294.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.80e-12	46.6	173	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++l d++aq+ ++Lt+kkG+++ +i  ++++ gW+++ k+++g +Gl+P+ + e 
   Q: 173  IALGDFMAQQVGDLTFKKGEILCII--KKNSDGWWMA-KNAKGNKGLIPKTYLEP 224
           5788*********************..9999******.7************9886 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MLARRQRDPL QSLQRRSQEL KQQVDGLLFE SQLKGALEAS KRRDMYQRKF RCIQLKQAID 60
ENKNALQKLK KADEPAPVGN YYQKKEEEHN LLDKLTHQLQ ELAVSISREN VTETGALTER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGGCGA GGCGGCAGCG CGACCCACTC CAGTCCTTGC AGCGCCGCAG TCAGGAGCTG 60
AAGCAGCAGG TACCGTCTGG TGAGAGACCT GGGCTCTGGA GGCGGGCGAG CTCCGGGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR030642--NPHP1_SH3
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0031514--C:motile cilium
GO:1903348--P:positive regulation of bicellular tight junction assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001244	Ailuropoda melanoleuca	74.77	0.00e+00	967.00
IUUC-Aca-004918	Anolis carolinensis	64.29	0.00e+00	686.00
IUUC-Ame-011864	Astyanax mexicanus	51.08	3.00e-111	395.00
IUUC-Bta-013182	Bos taurus	89.71	0.00e+00	1062.00
IUUC-Cpo-022082	Cavia porcellus	70.61	0.00e+00	858.00
IUUC-Csa-023896	Chlorocebus sabaeus	73.12	0.00e+00	939.00
IUUC-Cin-025783	Ciona intestinalis	41.01	1.00e-109	390.00
IUUC-Csv-026201	Ciona savignyi	42.05	4.00e-115	408.00
IUUC-Dre-028081	Danio rerio	46.41	8.00e-158	550.00
IUUC-Eca-034408	Equus caballus	76.35	0.00e+00	958.00
IUUC-Fca-036474	Felis catus	80.43	0.00e+00	969.00
IUUC-Ggo-045393	Gorilla gorilla	75.90	0.00e+00	787.00
IUUC-Hsa-046780	Homo sapiens	83.37	0.00e+00	704.00
IUUC-Lch-050573	Latimeria chalumnae	64.45	6.00e-97	348.00
IUUC-Loc-052676	Lepisosteus oculatus	57.09	4.00e-173	601.00
IUUC-Laf-053900	Loxodonta africana	76.83	0.00e+00	924.00
IUUC-Mcc-054917	Macaca mulatta	70.00	0.00e+00	909.00
IUUC-Mmr-061199	Microcebus murinus	75.09	0.00e+00	746.00
IUUC-Mmu-063617	Mus musculus	71.75	0.00e+00	932.00
IUUC-Mpu-066620	Mustela putorius furo	81.10	0.00e+00	981.00
IUUC-Mlu-067415	Myotis lucifugus	77.25	0.00e+00	901.00
IUUC-Nle-069490	Nomascus leucogenys	70.66	0.00e+00	895.00
IUUC-Ocu-073831	Oryctolagus cuniculus	74.89	0.00e+00	952.00
IUUC-Oga-088746	Otolemur garnettii	78.84	0.00e+00	914.00
IUUC-Ptr-090981	Pan troglodytes	83.14	0.00e+00	706.00
IUUC-Pan-092695	Papio anubis	73.27	0.00e+00	937.00
IUUC-Psi-093354	Pelodiscus sinensis	69.47	0.00e+00	738.00
IUUC-Pab-098055	Pongo abelii	80.90	0.00e+00	711.00
IUUC-Spo-108159	Schizosaccharomyces pombe	36.92	2.00e-07	48.10
IUUC-Tni-120650	Tetraodon nigroviridis	46.34	4.00e-128	452.00
IUUC-Ttr-129276	Tursiops truncatus	72.62	8.00e-82	297.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence