iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005395

UUCD1 version

UUC-AnC-00021

Ensembl Protein ID

ENSACAP00000005467.3

UniProt Accession

H9GAD0; H9GAD0_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000005482.3	ENSACAT00000005586.3	ENSACAP00000005467.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.50e-21	74.7	42	107
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.50e-10	39.5	141	171

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg+ +f+ah+ivLaas ++F+a+f++++ e k ++++++++++p++++al++F Y g l +
   Q: 42   CDVTLKVGDHKFSAHRIVLAASIPYFHAMFTNDMMECK-QDEIVMQGMDPSALEALINFAYNGHLAI 107
           9*************************************.************************9875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Nclg+++fA+++ c  L+daa++fi++hF
   Q: 141  PKNCLGVRQFAETMMCAVLYDAANSFIHQHF 171
           68***************************** PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MLETAGPDPE LDPEDLVHFS VGDLPSRGYG VMGEIRRQGK LCDVTLKVGD HKFSAHRIVL 60
AASIPYFHAM FTNDMMECKQ DEIVMQGMDP SALEALINFA YNGHLAIDQQ NVQSLLMGAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCCCTCCT GGTGACGTCA GCGAGGCTTC AAGCGCAAAG AGGGCGGGGC GTCACGCCAA 60
GAAGGGGACG TCACTTCCGG TACCTCTCTC AGTCTCTCAG TGGAAACGGT GCGGCGACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001536	Ailuropoda melanoleuca	90.62	0.00e+00	1078.00
IUUC-Apl-003270	Anas platyrhynchos	89.64	0.00e+00	991.00
IUUC-Bta-013481	Bos taurus	89.82	0.00e+00	1072.00
IUUC-Cel-018622	Caenorhabditis elegans	43.76	1.00e-140	493.00
IUUC-Cja-019847	Callithrix jacchus	90.80	0.00e+00	1085.00
IUUC-Cfa-020341	Canis familiaris	91.15	0.00e+00	1085.00
IUUC-Cpo-021613	Cavia porcellus	88.64	0.00e+00	1003.00
IUUC-Csa-023611	Chlorocebus sabaeus	90.80	0.00e+00	1088.00
IUUC-Cho-024605	Choloepus hoffmanni	77.59	5.00e-127	447.00
IUUC-Cin-025289	Ciona intestinalis	53.52	0.00e+00	634.00
IUUC-Dre-028248	Danio rerio	84.70	0.00e+00	1016.00
IUUC-Dno-029609	Dasypus novemcinctus	90.62	0.00e+00	1086.00
IUUC-Dor-030541	Dipodomys ordii	91.80	8.00e-143	499.00
IUUC-Dme-032107	Drosophila melanogaster	56.14	0.00e+00	665.00
IUUC-Eca-033507	Equus caballus	91.17	0.00e+00	1028.00
IUUC-Eeu-034750	Erinaceus europaeus	83.24	0.00e+00	916.00
IUUC-Fca-035731	Felis catus	91.33	0.00e+00	1090.00
IUUC-Fal-036959	Ficedula albicollis	92.91	0.00e+00	1070.00
IUUC-Gga-040166	Gallus gallus	93.30	0.00e+00	1109.00
IUUC-Ggo-044853	Gorilla gorilla	90.44	0.00e+00	1082.00
IUUC-Hsa-046437	Homo sapiens	90.27	0.00e+00	1078.00
IUUC-Itr-048529	Ictidomys tridecemlineatus	89.20	0.00e+00	990.00
IUUC-Lch-050195	Latimeria chalumnae	79.40	0.00e+00	915.00
IUUC-Loc-051787	Lepisosteus oculatus	86.95	0.00e+00	983.00
IUUC-Laf-053489	Loxodonta africana	90.97	0.00e+00	1084.00
IUUC-Mcc-055250	Macaca mulatta	90.00	0.00e+00	1082.00
IUUC-Meu-056871	Macropus eugenii	86.81	0.00e+00	1016.00
IUUC-Mtr-058180	Medicago truncatula	34.93	5.00e-38	152.00
IUUC-Mga-059425	Meleagris gallopavo	93.12	0.00e+00	1103.00
IUUC-Mmr-061394	Microcebus murinus	90.18	0.00e+00	1080.00
IUUC-Mdo-062285	Monodelphis domestica	93.23	0.00e+00	1105.00
IUUC-Mmu-063975	Mus musculus	90.18	0.00e+00	1080.00
IUUC-Mpu-066369	Mustela putorius furo	90.62	0.00e+00	1083.00
IUUC-Mlu-067832	Myotis lucifugus	88.04	0.00e+00	994.00
IUUC-Nle-069338	Nomascus leucogenys	83.95	0.00e+00	968.00
IUUC-Opr-071035	Ochotona princeps	79.28	0.00e+00	873.00
IUUC-Ont-071440	Oreochromis niloticus	83.63	0.00e+00	970.00
IUUC-Ola-087275	Oryzias latipes	82.37	0.00e+00	957.00
IUUC-Oga-087921	Otolemur garnettii	91.15	0.00e+00	1087.00
IUUC-Oar-089968	Ovis aries	83.74	0.00e+00	965.00
IUUC-Ptr-091272	Pan troglodytes	90.44	0.00e+00	1082.00
IUUC-Pan-092629	Papio anubis	90.62	0.00e+00	1084.00
IUUC-Psi-093456	Pelodiscus sinensis	93.25	0.00e+00	984.00
IUUC-Pma-094509	Petromyzon marinus	69.56	0.00e+00	794.00
IUUC-Pfo-096450	Poecilia formosa	80.25	0.00e+00	957.00
IUUC-Pab-097917	Pongo abelii	90.27	0.00e+00	1082.00
IUUC-Pop-099153	Populus trichocarpa	33.62	5.00e-35	142.00
IUUC-Pca-100330	Procavia capensis	91.72	6.00e-160	557.00
IUUC-Pva-103189	Pteropus vampyrus	91.33	0.00e+00	1088.00
IUUC-Pyt-104758	Pyrenophora triticirepentis	34.94	5.00e-07	47.80
IUUC-Sha-107283	Sarcophilus harrisii	92.83	0.00e+00	1070.00
IUUC-Sly-111482	Solanum lycopersicum	37.56	4.00e-41	162.00
IUUC-Stu-112032	Solanum tuberosum	37.56	6.00e-41	162.00
IUUC-Sar-112989	Sorex araneus	90.96	0.00e+00	1014.00
IUUC-Tgu-117146	Taeniopygia guttata	84.07	0.00e+00	939.00
IUUC-Tru-118132	Takifugu rubripes	83.58	0.00e+00	950.00
IUUC-Tsy-119058	Tarsius syrichta	76.21	2.00e-125	442.00
IUUC-Tni-120892	Tetraodon nigroviridis	80.60	0.00e+00	950.00
IUUC-Tme-127209	Tuber melanosporum	26.06	3.00e-05	44.30
IUUC-Tbe-127347	Tupaia belangeri	89.03	0.00e+00	1055.00
IUUC-Ttr-128343	Tursiops truncatus	69.87	0.00e+00	737.00
IUUC-Vpa-130796	Vicugna pacos	79.12	0.00e+00	909.00
IUUC-Xtr-132077	Xenopus tropicalis	84.96	0.00e+00	967.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence