iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022401

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02032988

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000013408.3	ENSCPOT00000013539.2	ENSCPOP00000012070.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.00e-104	348.6	746	1083

Active Site

Position(s)	Description	Evidence
1051	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +    ++++flGr+lgkal++
   Q: 746  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPSPAAQMLVGD-SFARHYYFLGRMLGKALYE 831
           689**********99**9*********************************************9965.99***************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++ +f+++llg+  ++++++l+++dpe+y++l ++k++ e d+eelgl++t+   ++ lge++++eLk gG++ipVt +N
   Q: 832  NMLVELPFAGFFLSKLLGTtaDVDIHHLASLDPEVYRNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKFGGKDIPVTSAN 915
           ******************9667999******************99.78999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i+ ++ afr+G+ +v++le+l++F+++e+++li+G    i++edlk++t+y ggy++d+p+i+ Fw+v+e+
   Q: 916  RIAYIHLVADYRLNKQIRPHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAqVPISLEDLKSFTNYSGGYSADHPVIKIFWRVVEG 1002
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd +rlP+++TC+n+LkLPe+  +  l++kLlyAie ++gFels
   Q: 1003 FTDEEKRKLLKFVTSCSRPPLLGFKELYPA-FCIHNGGSDlERLPTASTCMNLLKLPEFYDEALLRSKLLYAIECAAGFELS 1083
           ****************************88.*****99999**************************************985 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MFSFEGDFKT RPKVSLGGAS RKEEKASLLH RTQEERRKRE EERRRLKNAI IIQSFIRGYR 60
DRKQQYSLQR SAFDRCANAA QLGGTFSLGS GPNLTVLVRQ LLFFYKQSED SKRLIWLYQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCAGCT TCGAGGGTGA CTTCAAGAAC GCGGCCCAAG GTGTCCCTCG GCGGCGCAAG 60
CAGGAAGGTG CGCGGGGCGC GGGGCGGCCT CTCCGGACCG GGGCGCGAGC GTGGTGGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	90.03	0.00e+00	1904.00
IUUC-Apl-003731	Anas platyrhynchos	88.76	0.00e+00	1899.00
IUUC-Aca-005248	Anolis carolinensis	86.89	0.00e+00	1880.00
IUUC-Aly-005768	Arabidopsis lyrata	35.17	3.00e-107	383.00
IUUC-Ath-006576	Arabidopsis thaliana	35.33	8.00e-107	381.00
IUUC-Ago-007748	Ashbya gossypii	41.84	7.00e-77	282.00
IUUC-Acl-008158	Aspergillus clavatus	37.95	8.00e-76	279.00
IUUC-Afl-008398	Aspergillus flavus	34.02	8.00e-78	285.00
IUUC-Afu-008937	Aspergillus fumigatus	33.60	3.00e-80	293.00
IUUC-Ani-009252	Aspergillus nidulans	38.38	1.00e-81	298.00
IUUC-Ang-009773	Aspergillus niger	34.25	4.00e-78	286.00
IUUC-Aor-009940	Aspergillus oryzae	34.02	1.00e-77	285.00
IUUC-Ate-010395	Aspergillus terreus	39.02	2.00e-76	281.00
IUUC-Ame-010769	Astyanax mexicanus	63.36	0.00e+00	1040.00
IUUC-Bgr-012269	Blumeria graminis	37.83	4.00e-74	271.00
IUUC-Bta-012841	Bos taurus	90.23	0.00e+00	1922.00
IUUC-Bci-013743	Botrytis cinerea	29.76	7.00e-85	309.00
IUUC-Bol-015390	Brassica oleracea	45.87	4.00e-100	359.00
IUUC-Bra-016853	Brassica rapa	35.11	1.00e-105	377.00
IUUC-Cel-018638	Caenorhabditis elegans	39.37	2.00e-89	323.00
IUUC-Cja-019743	Callithrix jacchus	90.89	0.00e+00	1917.00
IUUC-Cfa-021031	Canis familiaris	91.45	0.00e+00	1953.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	44.50	2.00e-85	309.00
IUUC-Csa-024107	Chlorocebus sabaeus	93.17	0.00e+00	1984.00
IUUC-Cho-024750	Choloepus hoffmanni	82.50	0.00e+00	801.00
IUUC-Cin-025432	Ciona intestinalis	44.88	1.00e-97	350.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.32	2.00e-87	317.00
IUUC-Cne-026841	Cryptococcus neoformans	35.60	1.00e-93	337.00
IUUC-Cme-027265	Cyanidioschyzon merolae	46.38	8.00e-102	365.00
IUUC-Dre-028196	Danio rerio	77.65	0.00e+00	1595.00
IUUC-Dno-029024	Dasypus novemcinctus	92.71	0.00e+00	1983.00
IUUC-Dor-030483	Dipodomys ordii	91.12	0.00e+00	684.00
IUUC-Dse-031416	Dothistroma septosporum	33.56	8.00e-78	285.00
IUUC-Dme-031946	Drosophila melanogaster	36.78	0.00e+00	681.00
IUUC-Ete-032240	Echinops telfairi	79.76	5.00e-171	595.00
IUUC-Eca-033828	Equus caballus	91.71	0.00e+00	1935.00
IUUC-Eeu-034604	Erinaceus europaeus	85.38	3.00e-127	449.00
IUUC-Fca-035907	Felis catus	90.41	0.00e+00	1952.00
IUUC-Fal-037389	Ficedula albicollis	88.75	0.00e+00	1920.00
IUUC-Fox-037788	Fusarium oxysporum	37.97	1.00e-93	338.00
IUUC-Fso-038088	Fusarium solani	36.20	2.00e-89	324.00
IUUC-Gmo-039254	Gadus morhua	67.23	0.00e+00	1236.00
IUUC-Ggr-039941	Gaeumannomyces graminis	34.08	7.00e-83	302.00
IUUC-Gga-040310	Gallus gallus	88.38	0.00e+00	1913.00
IUUC-Gac-042054	Gasterosteus aculeatus	70.00	0.00e+00	1305.00
IUUC-Ggo-045031	Gorilla gorilla	93.54	0.00e+00	1991.00
IUUC-Hsa-045880	Homo sapiens	93.44	0.00e+00	1989.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	89.57	0.00e+00	712.00
IUUC-Kpa-049307	Komagataella pastoris	36.52	1.00e-64	241.00
IUUC-Lch-050403	Latimeria chalumnae	81.55	0.00e+00	1675.00
IUUC-Lpe-051428	Leersia perrieri	46.65	2.00e-96	347.00
IUUC-Loc-052218	Lepisosteus oculatus	81.47	0.00e+00	1703.00
IUUC-Lma-053096	Leptosphaeria maculans	38.58	6.00e-80	293.00
IUUC-Laf-054162	Loxodonta africana	86.97	0.00e+00	1653.00
IUUC-Mcc-055127	Macaca mulatta	93.26	0.00e+00	1985.00
IUUC-Meu-056187	Macropus eugenii	81.30	1.00e-104	374.00
IUUC-Mor-057021	Magnaporthe oryzae	34.49	2.00e-78	288.00
IUUC-Mpo-057570	Magnaporthe poae	36.24	4.00e-75	276.00
IUUC-Mla-059124	Melampsora laricipopulina	48.03	4.00e-101	361.00
IUUC-Mga-059581	Meleagris gallopavo	88.50	0.00e+00	1902.00
IUUC-Mvi-060445	Microbotryum violaceum	37.91	4.00e-104	372.00
IUUC-Mmr-061360	Microcebus murinus	88.84	0.00e+00	1819.00
IUUC-Mdo-062194	Monodelphis domestica	85.20	0.00e+00	1908.00
IUUC-Mmu-064189	Mus musculus	92.71	0.00e+00	1991.00
IUUC-Mac-065275	Musa acuminata	49.39	1.00e-108	387.00
IUUC-Mpu-066439	Mustela putorius furo	91.01	0.00e+00	1906.00
IUUC-Mlu-068228	Myotis lucifugus	87.17	0.00e+00	1873.00
IUUC-Nfi-068280	Neosartorya fischeri	38.43	1.00e-78	288.00
IUUC-Ncr-068869	Neurospora crassa	35.96	6.00e-83	302.00
IUUC-Nle-069687	Nomascus leucogenys	93.12	0.00e+00	1934.00
IUUC-Opr-070592	Ochotona princeps	75.65	2.00e-122	433.00
IUUC-Ont-071836	Oreochromis niloticus	78.39	0.00e+00	1658.00
IUUC-Oan-072800	Ornithorhynchus anatinus	89.76	0.00e+00	1920.00
IUUC-Ocu-074587	Oryctolagus cuniculus	94.00	0.00e+00	2003.00
IUUC-Ola-087209	Oryzias latipes	77.93	0.00e+00	1631.00
IUUC-Olu-087699	Ostreococcus lucimarinus	42.86	4.00e-86	311.00
IUUC-Oga-088776	Otolemur garnettii	87.90	0.00e+00	1795.00
IUUC-Oar-089441	Ovis aries	89.50	0.00e+00	1900.00
IUUC-Ptr-091273	Pan troglodytes	93.35	0.00e+00	1987.00
IUUC-Pan-091981	Papio anubis	93.26	0.00e+00	1986.00
IUUC-Psi-093203	Pelodiscus sinensis	87.15	0.00e+00	1645.00
IUUC-Pma-094738	Petromyzon marinus	65.69	0.00e+00	1336.00
IUUC-Pno-095132	Phaeosphaeria nodorum	29.38	5.00e-60	226.00
IUUC-Ppa-095682	Physcomitrella patens	37.33	3.00e-111	396.00
IUUC-Pfo-097511	Poecilia formosa	78.58	0.00e+00	1670.00
IUUC-Pab-098634	Pongo abelii	90.31	0.00e+00	1906.00
IUUC-Pop-099574	Populus trichocarpa	41.65	3.00e-94	340.00
IUUC-Pca-100987	Procavia capensis	85.31	0.00e+00	858.00
IUUC-Pva-103034	Pteropus vampyrus	86.25	0.00e+00	1794.00
IUUC-Pgr-103513	Puccinia graminis	39.35	1.00e-106	381.00
IUUC-Ptt-103967	Puccinia triticina	41.52	5.00e-95	342.00
IUUC-Pte-104105	Pyrenophora teres	34.55	2.00e-81	297.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	37.72	4.00e-78	286.00
IUUC-Rno-105380	Rattus norvegicus	91.89	0.00e+00	1725.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.77	1.00e-67	251.00
IUUC-Sha-107108	Sarcophilus harrisii	82.14	0.00e+00	1748.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	42.96	9.00e-95	341.00
IUUC-Spo-108097	Schizosaccharomyces pombe	43.20	2.00e-93	337.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	30.35	5.00e-83	303.00
IUUC-Sar-113687	Sorex araneus	80.93	0.00e+00	903.00
IUUC-Sre-115038	Sporisorium reilianum	44.23	6.00e-97	349.00
IUUC-Ssc-116168	Sus scrofa	83.02	0.00e+00	781.00
IUUC-Tgu-116729	Taeniopygia guttata	88.57	0.00e+00	1915.00
IUUC-Tru-118068	Takifugu rubripes	77.01	0.00e+00	1620.00
IUUC-Tsy-118942	Tarsius syrichta	92.74	0.00e+00	709.00
IUUC-Tni-120732	Tetraodon nigroviridis	76.82	0.00e+00	1578.00
IUUC-Tre-121892	Trichoderma reesei	36.94	1.00e-88	321.00
IUUC-Tvi-122354	Trichoderma virens	36.22	3.00e-90	327.00
IUUC-Tme-127102	Tuber melanosporum	36.03	5.00e-92	333.00
IUUC-Tbe-127351	Tupaia belangeri	80.95	0.00e+00	1512.00
IUUC-Ttr-129061	Tursiops truncatus	87.82	0.00e+00	1855.00
IUUC-Uma-129343	Ustilago maydis	44.23	6.00e-98	352.00
IUUC-Vda-129748	Verticillium dahliae	38.60	9.00e-80	291.00
IUUC-Vvi-131234	Vitis vinifera	35.19	1.00e-101	364.00
IUUC-Xtr-132094	Xenopus tropicalis	84.90	0.00e+00	1775.00
IUUC-Xma-133923	Xiphophorus maculatus	78.58	0.00e+00	1668.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence