iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116926

Ensembl Protein ID

ENSTGUP00000005582.1

UniProt Accession

H0Z4T7; H0Z4T7_TAEGU

Genbank Protein ID

ENSTGUP00000005582

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01026293

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000005424.1	ENSTGUT00000005639.1	ENSTGUP00000005582.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.60e-15	56.7	135	189

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d+++++ +e  +kkGd++++   ++ +e W+++ ++ egk+G++P  +vek
   Q: 135  AEYVRALFDFNGND-EEDPFKKGDILRI--RDKPEEQWWNA-EDSEGKEGMIPVPYVEK 189
           689*******9865.5569*********..6999******9.5**************97 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MAGQFDSEDR ASWYWGRLSR AEAVSLLQGQ RHGTFLVRDS GTIPGDFVLS VSESSRVSHY 60
IVNSLGPAPG GPAARAPGPR VRSNPTRFRI GDQEFDSLPS LLEFYKIHYL DTTTLIEPVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGGGC AGTTCGACTC CGAGGACCGG GCGAGCTGGT ACTGGGGGCG GCTGAGCCGC 60
GCCGAGGCCG TATCGCTGCT GCAGGGGCAG CGCCACGGCA CCTTCCTGGT GCGCGACTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	86.33	8.00e-145	505.00
IUUC-Apl-003225	Anas platyrhynchos	92.83	9.00e-120	421.00
IUUC-Aca-004818	Anolis carolinensis	77.19	2.00e-89	320.00
IUUC-Ame-011721	Astyanax mexicanus	64.47	7.00e-112	396.00
IUUC-Bta-012320	Bos taurus	86.23	3.00e-147	513.00
IUUC-Cel-018307	Caenorhabditis elegans	30.98	2.00e-23	102.00
IUUC-Cja-019935	Callithrix jacchus	85.62	7.00e-153	532.00
IUUC-Cfa-021221	Canis familiaris	86.23	4.00e-147	513.00
IUUC-Cpo-021592	Cavia porcellus	80.07	5.00e-129	453.00
IUUC-Cho-024775	Choloepus hoffmanni	86.23	1.00e-148	518.00
IUUC-Cin-025128	Ciona intestinalis	44.04	2.00e-68	251.00
IUUC-Csv-026340	Ciona savignyi	42.65	3.00e-63	234.00
IUUC-Dre-027390	Danio rerio	65.94	2.00e-114	404.00
IUUC-Dno-029847	Dasypus novemcinctus	86.23	3.00e-147	513.00
IUUC-Dor-030360	Dipodomys ordii	80.66	4.00e-140	489.00
IUUC-Dme-031600	Drosophila melanogaster	44.07	2.00e-63	234.00
IUUC-Ete-032604	Echinops telfairi	89.64	3.00e-116	410.00
IUUC-Eca-033233	Equus caballus	85.90	1.00e-146	511.00
IUUC-Eeu-034642	Erinaceus europaeus	91.40	4.00e-119	419.00
IUUC-Fca-035955	Felis catus	91.44	8.00e-120	422.00
IUUC-Fal-037152	Ficedula albicollis	93.62	2.00e-150	524.00
IUUC-Gmo-038849	Gadus morhua	64.17	2.00e-111	394.00
IUUC-Gga-040861	Gallus gallus	89.51	5.00e-156	542.00
IUUC-Gac-041569	Gasterosteus aculeatus	62.77	2.00e-110	390.00
IUUC-Ggo-045475	Gorilla gorilla	86.23	3.00e-147	513.00
IUUC-Hsa-046008	Homo sapiens	86.23	3.00e-147	513.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	84.35	8.00e-119	419.00
IUUC-Lch-050509	Latimeria chalumnae	79.35	2.00e-143	501.00
IUUC-Loc-052229	Lepisosteus oculatus	70.04	8.00e-102	362.00
IUUC-Laf-053896	Loxodonta africana	85.11	4.00e-152	530.00
IUUC-Mcc-055280	Macaca mulatta	86.23	3.00e-147	513.00
IUUC-Meu-056783	Macropus eugenii	91.89	6.00e-120	422.00
IUUC-Mga-059345	Meleagris gallopavo	94.57	2.00e-122	430.00
IUUC-Mdo-062691	Monodelphis domestica	81.82	1.00e-143	501.00
IUUC-Mmu-063691	Mus musculus	85.90	4.00e-147	513.00
IUUC-Mpu-065737	Mustela putorius furo	86.23	3.00e-147	513.00
IUUC-Mlu-067005	Myotis lucifugus	84.59	5.00e-144	503.00
IUUC-Nle-070154	Nomascus leucogenys	91.44	1.00e-119	421.00
IUUC-Opr-071114	Ochotona princeps	85.29	9.00e-152	528.00
IUUC-Ont-071877	Oreochromis niloticus	64.63	1.00e-115	408.00
IUUC-Oan-072967	Ornithorhynchus anatinus	83.52	6.00e-121	426.00
IUUC-Olo-080293	Oryza longistaminata	36.00	3.10e+00	24.60
IUUC-Ola-086748	Oryzias latipes	54.52	2.00e-86	311.00
IUUC-Oga-088266	Otolemur garnettii	86.23	1.00e-147	514.00
IUUC-Oar-089221	Ovis aries	82.30	1.00e-143	501.00
IUUC-Ptr-091463	Pan troglodytes	82.30	2.00e-136	478.00
IUUC-Pan-092242	Papio anubis	85.90	3.00e-147	513.00
IUUC-Psi-093287	Pelodiscus sinensis	94.59	4.00e-123	432.00
IUUC-Pma-094340	Petromyzon marinus	58.18	2.00e-95	341.00
IUUC-Pfo-097378	Poecilia formosa	64.29	6.00e-108	383.00
IUUC-Pab-097823	Pongo abelii	82.35	1.00e-87	314.00
IUUC-Pca-101068	Procavia capensis	86.23	3.00e-147	513.00
IUUC-Rno-105288	Rattus norvegicus	85.90	5.00e-147	513.00
IUUC-Sar-113453	Sorex araneus	76.39	2.00e-131	461.00
IUUC-Tru-118656	Takifugu rubripes	64.02	6.00e-113	399.00
IUUC-Tni-120229	Tetraodon nigroviridis	60.18	3.00e-104	370.00
IUUC-Tbe-127436	Tupaia belangeri	82.62	1.00e-130	458.00
IUUC-Ttr-129109	Tursiops truncatus	91.89	3.00e-120	423.00
IUUC-Vpa-130527	Vicugna pacos	85.90	2.00e-145	507.00
IUUC-Xtr-131808	Xenopus tropicalis	80.00	7.00e-143	499.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence