iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013328

Ensembl Protein ID

ENSBTAP00000027619.5

UniProt Accession

F1MBM9; F1MBM9_BOVIN

Genbank Protein ID

ENSBTAP00000027619

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02034919

Gene Name

ARHGEF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000020726.5	ENSBTAT00000027619.5	ENSBTAP00000027619.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-14	54.2	167	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL++ kGdv++v     +++gW++g  + +g+ G fP+n+v++++
   Q: 167  VVRAKFNFQQTNEDELSFAKGDVIHVT--RVEEGGWWEG--THNGRTGWFPSNYVREVK 221
           78999*********************7..999*******..8**************996 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MNSAEQTVTW LITLGVLESP KKTISDPEGF LQASLKDGVV LCRLLERLLP GTIEKFYQEY 60
RLSEESLFLI NEFMRACDQS LKSETFDAND LYQGQNFNKV LSSLVTLNKV TADIGLGSDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATTCCG CCGAGCAGAC CGTTACGTGG CTCATTACCT TGGGCGTGCT GGAGTCGCCC 60
AAGAAAACCA TCTCGGACCC AGAGGGCTTC CTGCAGGCGT CTCTGAAGGA TGGGGTGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0000322--C:storage vacuole
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0048041--P:focal adhesion assembly
GO:0007030--P:Golgi organization
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0030032--P:lamellipodium assembly
GO:0043065--P:positive regulation of apoptotic process
GO:0010763--P:positive regulation of fibroblast migration
GO:0060124--P:positive regulation of growth hormone secretion
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0032092--P:positive regulation of protein binding
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:1904424--P:regulation of GTP binding
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001259	Ailuropoda melanoleuca	89.17	0.00e+00	1264.00
IUUC-Aca-004591	Anolis carolinensis	89.79	0.00e+00	1359.00
IUUC-Ame-010759	Astyanax mexicanus	74.88	0.00e+00	1249.00
IUUC-Cja-018742	Callithrix jacchus	94.19	0.00e+00	1179.00
IUUC-Cfa-020756	Canis familiaris	93.80	0.00e+00	1135.00
IUUC-Cpo-021284	Cavia porcellus	91.23	0.00e+00	1381.00
IUUC-Csa-023162	Chlorocebus sabaeus	93.85	0.00e+00	1496.00
IUUC-Cho-024736	Choloepus hoffmanni	72.90	1.00e-172	600.00
IUUC-Cin-025535	Ciona intestinalis	40.51	1.00e-94	340.00
IUUC-Cgl-026676	Colletotrichum gloeosporioides	42.86	1.00e-11	65.90
IUUC-Cne-026866	Cryptococcus neoformans	49.21	2.00e-12	68.90
IUUC-Dre-028646	Danio rerio	74.65	0.00e+00	1242.00
IUUC-Dno-029461	Dasypus novemcinctus	93.16	0.00e+00	1484.00
IUUC-Dor-030623	Dipodomys ordii	79.76	0.00e+00	1015.00
IUUC-Dme-032219	Drosophila melanogaster	45.75	1.00e-103	371.00
IUUC-Ete-032236	Echinops telfairi	78.82	0.00e+00	794.00
IUUC-Eca-034137	Equus caballus	95.25	0.00e+00	1362.00
IUUC-Fca-035742	Felis catus	93.24	0.00e+00	1110.00
IUUC-Fal-037205	Ficedula albicollis	92.91	0.00e+00	1186.00
IUUC-Gmo-039475	Gadus morhua	69.41	0.00e+00	1062.00
IUUC-Gga-040539	Gallus gallus	91.35	0.00e+00	959.00
IUUC-Gac-042615	Gasterosteus aculeatus	65.86	0.00e+00	969.00
IUUC-Ggo-044470	Gorilla gorilla	89.23	0.00e+00	1282.00
IUUC-Hsa-046398	Homo sapiens	90.53	0.00e+00	1299.00
IUUC-Kpa-049278	Komagataella pastoris	27.62	2.00e-17	84.70
IUUC-Loc-052146	Lepisosteus oculatus	83.78	0.00e+00	1359.00
IUUC-Laf-053891	Loxodonta africana	91.30	0.00e+00	1476.00
IUUC-Mcc-055483	Macaca mulatta	90.40	0.00e+00	1298.00
IUUC-Mga-059410	Meleagris gallopavo	90.73	0.00e+00	1322.00
IUUC-Mmr-060758	Microcebus murinus	93.26	0.00e+00	1268.00
IUUC-Mdo-061900	Monodelphis domestica	78.07	0.00e+00	1233.00
IUUC-Mmu-063849	Mus musculus	91.57	0.00e+00	1257.00
IUUC-Mpu-065876	Mustela putorius furo	93.82	0.00e+00	1134.00
IUUC-Mlu-067970	Myotis lucifugus	95.38	0.00e+00	1368.00
IUUC-Nle-069685	Nomascus leucogenys	76.45	0.00e+00	1023.00
IUUC-Opr-071132	Ochotona princeps	63.61	0.00e+00	708.00
IUUC-Ont-071815	Oreochromis niloticus	75.23	0.00e+00	1240.00
IUUC-Oan-073057	Ornithorhynchus anatinus	92.48	0.00e+00	1202.00
IUUC-Ola-086663	Oryzias latipes	72.22	0.00e+00	1054.00
IUUC-Oga-088103	Otolemur garnettii	94.48	0.00e+00	1306.00
IUUC-Ptr-091162	Pan troglodytes	89.46	0.00e+00	1191.00
IUUC-Pan-092093	Papio anubis	84.45	0.00e+00	1347.00
IUUC-Pma-094701	Petromyzon marinus	60.96	5.00e-125	441.00
IUUC-Pfo-096736	Poecilia formosa	67.09	0.00e+00	1047.00
IUUC-Pab-097641	Pongo abelii	92.84	0.00e+00	1259.00
IUUC-Pva-102819	Pteropus vampyrus	89.88	0.00e+00	1249.00
IUUC-Pte-104123	Pyrenophora teres	45.00	2.00e-10	61.60
IUUC-Rno-106099	Rattus norvegicus	92.23	0.00e+00	1428.00
IUUC-Sha-106845	Sarcophilus harrisii	91.10	0.00e+00	1101.00
IUUC-Sja-107728	Schizosaccharomyces japonicus	22.80	1.00e-11	65.10
IUUC-Ssc-116036	Sus scrofa	95.07	0.00e+00	1130.00
IUUC-Tgu-117498	Taeniopygia guttata	87.82	0.00e+00	1381.00
IUUC-Tru-118278	Takifugu rubripes	72.01	0.00e+00	1068.00
IUUC-Tsy-118990	Tarsius syrichta	91.72	0.00e+00	952.00
IUUC-Tni-120852	Tetraodon nigroviridis	73.53	0.00e+00	983.00
IUUC-Ttr-128922	Tursiops truncatus	87.50	0.00e+00	1122.00
IUUC-Xtr-132012	Xenopus tropicalis	83.89	0.00e+00	1244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence