iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117498

Ensembl Protein ID

ENSTGUP00000009169.1

UniProt Accession

H0ZF07; H0ZF07_TAEGU

Genbank Protein ID

ENSTGUP00000009169

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01012713

Gene Name

ARHGEF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000008859.1	ENSTGUT00000009268.1	ENSTGUP00000009169.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-15	56.7	167	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL++ kGd+++v     +++gW++g  +l+gk G fP+n+v++++
   Q: 167  VVRAKFNFQQTNEDELSFSKGDIIHVT--RVEEGGWWEG--TLNGKTGWFPSNYVREIK 221
           68999*********************7..999*******..8**************997 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MNSAEQTVTW LIALGVLDSL RKQRTFFELH AQAAIHLNRN FCFLVTVIPP PLLLQVYPEP 60
RTEGECMSNI REFLRGCGAS LRLETFDAND LYQGQNFSKV LSSLVALNKV TADIGLGSDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATTCGG CGGAGCAGAC CGTTACGTGG CTGATCGCCC TGGGCGTGCT GGAGTCGCCC 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00169--PH
PF00621--RhoGEF
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0000322--C:storage vacuole
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0048041--P:focal adhesion assembly
GO:0007030--P:Golgi organization
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0030032--P:lamellipodium assembly
GO:0043065--P:positive regulation of apoptotic process
GO:0010763--P:positive regulation of fibroblast migration
GO:0060124--P:positive regulation of growth hormone secretion
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0032092--P:positive regulation of protein binding
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:1904424--P:regulation of GTP binding
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001259	Ailuropoda melanoleuca	87.52	0.00e+00	1236.00
IUUC-Aca-004591	Anolis carolinensis	91.88	0.00e+00	1388.00
IUUC-Ame-010759	Astyanax mexicanus	73.50	0.00e+00	1230.00
IUUC-Bgr-012305	Blumeria graminis	41.43	2.00e-11	64.70
IUUC-Bta-013328	Bos taurus	87.82	0.00e+00	1412.00
IUUC-Cja-018742	Callithrix jacchus	93.21	0.00e+00	1176.00
IUUC-Cfa-020756	Canis familiaris	92.22	0.00e+00	1120.00
IUUC-Cpo-021284	Cavia porcellus	90.75	0.00e+00	1350.00
IUUC-Csa-023162	Chlorocebus sabaeus	91.18	0.00e+00	1453.00
IUUC-Cho-024736	Choloepus hoffmanni	74.34	2.00e-173	602.00
IUUC-Cin-025535	Ciona intestinalis	40.90	2.00e-95	342.00
IUUC-Cne-026866	Cryptococcus neoformans	56.86	2.00e-13	71.20
IUUC-Dre-028646	Danio rerio	73.50	0.00e+00	1219.00
IUUC-Dno-029461	Dasypus novemcinctus	92.23	0.00e+00	1461.00
IUUC-Dor-030623	Dipodomys ordii	80.46	0.00e+00	1038.00
IUUC-Dme-032219	Drosophila melanogaster	46.77	1.00e-104	374.00
IUUC-Ete-032236	Echinops telfairi	80.04	0.00e+00	798.00
IUUC-Eca-034137	Equus caballus	94.61	0.00e+00	1348.00
IUUC-Fca-035742	Felis catus	90.26	0.00e+00	1091.00
IUUC-Fal-037205	Ficedula albicollis	100.00	0.00e+00	1271.00
IUUC-Fox-037757	Fusarium oxysporum	40.28	3.00e-12	67.80
IUUC-Fso-038433	Fusarium solani	40.28	3.00e-12	67.40
IUUC-Gmo-039475	Gadus morhua	66.74	0.00e+00	1028.00
IUUC-Gga-040539	Gallus gallus	81.99	0.00e+00	1029.00
IUUC-Gac-042615	Gasterosteus aculeatus	63.19	0.00e+00	924.00
IUUC-Ggo-044470	Gorilla gorilla	88.59	0.00e+00	1278.00
IUUC-Hsa-046398	Homo sapiens	87.75	0.00e+00	1258.00
IUUC-Kpa-049278	Komagataella pastoris	27.20	3.00e-18	87.00
IUUC-Loc-052146	Lepisosteus oculatus	84.70	0.00e+00	1358.00
IUUC-Lma-053273	Leptosphaeria maculans	40.32	5.00e-11	63.50
IUUC-Laf-053891	Loxodonta africana	88.52	0.00e+00	1420.00
IUUC-Mcc-055483	Macaca mulatta	87.63	0.00e+00	1257.00
IUUC-Mga-059410	Meleagris gallopavo	96.61	0.00e+00	1402.00
IUUC-Mmr-060758	Microcebus murinus	90.01	0.00e+00	1217.00
IUUC-Mdo-061900	Monodelphis domestica	79.12	0.00e+00	1249.00
IUUC-Mmu-063849	Mus musculus	88.20	0.00e+00	1208.00
IUUC-Mpu-065876	Mustela putorius furo	90.91	0.00e+00	1113.00
IUUC-Mlu-067970	Myotis lucifugus	94.87	0.00e+00	1352.00
IUUC-Ncr-068791	Neurospora crassa	47.37	5.00e-12	66.60
IUUC-Nle-069685	Nomascus leucogenys	75.89	0.00e+00	1026.00
IUUC-Opr-071132	Ochotona princeps	61.86	0.00e+00	687.00
IUUC-Ont-071815	Oreochromis niloticus	73.61	0.00e+00	1216.00
IUUC-Oan-073057	Ornithorhynchus anatinus	95.46	0.00e+00	1237.00
IUUC-Ola-086663	Oryzias latipes	74.35	0.00e+00	1107.00
IUUC-Oga-088103	Otolemur garnettii	92.47	0.00e+00	1287.00
IUUC-Ptr-091162	Pan troglodytes	90.93	0.00e+00	1224.00
IUUC-Pan-092093	Papio anubis	81.63	0.00e+00	1305.00
IUUC-Pma-094701	Petromyzon marinus	56.74	7.00e-127	446.00
IUUC-Pfo-096736	Poecilia formosa	66.40	0.00e+00	1046.00
IUUC-Pab-097641	Pongo abelii	77.73	0.00e+00	1221.00
IUUC-Pva-102819	Pteropus vampyrus	87.16	0.00e+00	1198.00
IUUC-Pte-104123	Pyrenophora teres	46.55	5.00e-11	63.50
IUUC-Pyt-104567	Pyrenophora triticirepentis	47.06	1.00e-10	62.40
IUUC-Rno-106099	Rattus norvegicus	89.21	0.00e+00	1380.00
IUUC-Sha-106845	Sarcophilus harrisii	80.43	0.00e+00	1148.00
IUUC-Sja-107728	Schizosaccharomyces japonicus	23.81	7.00e-10	58.90
IUUC-Ssc-116036	Sus scrofa	91.27	0.00e+00	1094.00
IUUC-Tru-118278	Takifugu rubripes	73.19	0.00e+00	1104.00
IUUC-Tsy-118990	Tarsius syrichta	90.63	0.00e+00	941.00
IUUC-Tni-120852	Tetraodon nigroviridis	70.73	0.00e+00	945.00
IUUC-Tre-121917	Trichoderma reesei	45.61	4.00e-12	67.40
IUUC-Tvi-122534	Trichoderma virens	45.61	4.00e-12	67.00
IUUC-Ttr-128922	Tursiops truncatus	86.01	0.00e+00	1110.00
IUUC-Xtr-132012	Xenopus tropicalis	83.66	0.00e+00	1220.00
IUUC-Xma-133901	Xiphophorus maculatus	63.21	0.00e+00	998.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence