iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062839

Ensembl Protein ID

ENSMODP00000014142.1

UniProt Accession

F6WYW6; F6WYW6_MONDO

Protein Name

Uncharacterized protein

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000011304.2	ENSMODT00000014404.2	ENSMODP00000014142.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	5.20e-49	167.4	30	223

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+sv+++t+l+eC+++fC++Clkqy++l ++eg+ + i+cp++ c ++  l+esei++ lv  ++++ +++l++e++v+ d+++
   Q: 30   CKLCLCEYSVDKMTTLQECQCIFCTSCLKQYVQLSVREGCGSPITCPDMVCLNRgtLQESEISC-LVPVDQFQLFQRLKFEREVHLDPCR 118
           ****************************************************98889*******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+ +e+++  + ++vec++c+ +fC++Ck++wH+++sC++    +   +  ++ a     +ea +k+Cp C+vyie+neg
   Q: 119  TWCPVADCQTVCHIEQSDsgQPTKVECPSCHLTFCSCCKDTWHADRSCRDSPPVVVLPT--EHGALIGVDAEAPIKQCPVCRVYIERNEG 206
           *************999887899999****************************999988..5788889999******************* PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 207  CAQMMCKNCKHTFCWYC 223
           ***************** PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MGSVGELCYH PITMEKPATG ELTLDPLVTC KLCLCEYSVD KMTTLQECQC IFCTSCLKQY 60
VQLSVREGCG SPITCPDMVC LNRGTLQESE ISCLVPVDQF QLFQRLKFER EVHLDPCRTW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAATTAGTT CCAGTGAGTT GTGTCTGTGG CCCTTGGAGA GAGGAATGAA AGAGATCGTG 60
ATGCCATGGA GTTGATAGGA GCCATATAAC CAAGGTACAA GTATGGAGAA GTTGATAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

mdo:100025103

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	84.21	4.00e-152	530.00
IUUC-Apl-004112	Anas platyrhynchos	79.08	5.00e-128	450.00
IUUC-Aca-004533	Anolis carolinensis	78.95	3.00e-142	497.00
IUUC-Aly-006073	Arabidopsis lyrata	31.02	1.00e-13	69.70
IUUC-Ath-007704	Arabidopsis thaliana	31.68	1.00e-13	70.90
IUUC-Bta-012641	Bos taurus	84.59	1.00e-151	528.00
IUUC-Cja-019626	Callithrix jacchus	73.68	8.00e-129	452.00
IUUC-Cfa-020702	Canis familiaris	84.54	7.00e-153	532.00
IUUC-Cpo-022147	Cavia porcellus	85.20	3.00e-151	527.00
IUUC-Csa-023473	Chlorocebus sabaeus	86.18	2.00e-154	537.00
IUUC-Cho-024298	Choloepus hoffmanni	80.23	7.00e-123	432.00
IUUC-Dre-028099	Danio rerio	63.30	2.00e-90	325.00
IUUC-Dno-029122	Dasypus novemcinctus	81.31	2.00e-144	504.00
IUUC-Dor-030669	Dipodomys ordii	89.74	1.00e-123	435.00
IUUC-Ete-033141	Echinops telfairi	73.36	1.00e-117	415.00
IUUC-Eca-034360	Equus caballus	86.18	1.00e-154	538.00
IUUC-Eeu-034538	Erinaceus europaeus	70.09	1.00e-80	292.00
IUUC-Fca-036055	Felis catus	84.21	5.00e-150	523.00
IUUC-Fal-037339	Ficedula albicollis	77.50	7.00e-131	459.00
IUUC-Gmo-038780	Gadus morhua	61.62	5.00e-86	310.00
IUUC-Gga-040256	Gallus gallus	77.30	5.00e-130	456.00
IUUC-Gac-042127	Gasterosteus aculeatus	61.65	3.00e-90	324.00
IUUC-Ggo-044867	Gorilla gorilla	85.86	5.00e-154	536.00
IUUC-Hsa-046928	Homo sapiens	85.86	4.00e-154	536.00
IUUC-Hvu-047484	Hordeum vulgare	31.19	2.00e-17	83.60
IUUC-Itr-048250	Ictidomys tridecemlineatus	91.24	9.00e-102	362.00
IUUC-Lch-050168	Latimeria chalumnae	73.77	4.00e-134	470.00
IUUC-Lpe-051649	Leersia perrieri	29.76	4.00e-17	83.60
IUUC-Loc-052150	Lepisosteus oculatus	61.45	4.00e-88	317.00
IUUC-Laf-053967	Loxodonta africana	85.53	2.00e-153	534.00
IUUC-Mcc-055898	Macaca mulatta	86.18	2.00e-154	537.00
IUUC-Meu-056628	Macropus eugenii	97.44	1.00e-43	169.00
IUUC-Mga-059820	Meleagris gallopavo	76.95	2.00e-129	454.00
IUUC-Mmr-060680	Microcebus murinus	85.53	1.00e-152	531.00
IUUC-Mmu-063339	Mus musculus	81.91	5.00e-137	480.00
IUUC-Mac-065414	Musa acuminata	29.49	8.00e-19	87.80
IUUC-Mpu-065973	Mustela putorius furo	84.21	1.00e-151	528.00
IUUC-Mlu-067112	Myotis lucifugus	84.87	3.00e-144	504.00
IUUC-Nle-069795	Nomascus leucogenys	85.86	2.00e-154	538.00
IUUC-Opr-070390	Ochotona princeps	79.61	2.00e-135	475.00
IUUC-Ont-072329	Oreochromis niloticus	61.34	3.00e-90	324.00
IUUC-Oan-072980	Ornithorhynchus anatinus	74.76	2.00e-133	468.00
IUUC-Ocu-073845	Oryctolagus cuniculus	85.53	1.00e-152	531.00
IUUC-Ola-086872	Oryzias latipes	60.67	2.00e-84	305.00
IUUC-Oga-088954	Otolemur garnettii	84.21	5.00e-152	530.00
IUUC-Oar-089879	Ovis aries	85.25	2.00e-152	531.00
IUUC-Ptr-090685	Pan troglodytes	85.86	4.00e-154	536.00
IUUC-Pan-092086	Papio anubis	86.51	2.00e-154	538.00
IUUC-Psi-093481	Pelodiscus sinensis	78.29	2.00e-135	474.00
IUUC-Pfo-096065	Poecilia formosa	63.02	2.00e-89	322.00
IUUC-Pab-098031	Pongo abelii	85.53	5.00e-153	533.00
IUUC-Pca-100936	Procavia capensis	83.88	7.00e-151	526.00
IUUC-Pva-102864	Pteropus vampyrus	75.99	2.00e-131	461.00
IUUC-Rno-105503	Rattus norvegicus	81.91	3.00e-137	480.00
IUUC-Sha-107425	Sarcophilus harrisii	93.09	1.00e-169	588.00
IUUC-Stu-112736	Solanum tuberosum	29.09	5.00e-18	84.70
IUUC-Ssc-115458	Sus scrofa	84.74	3.00e-142	497.00
IUUC-Tgu-117226	Taeniopygia guttata	77.50	1.00e-131	462.00
IUUC-Tru-118362	Takifugu rubripes	62.55	4.00e-91	327.00
IUUC-Tsy-119255	Tarsius syrichta	86.18	3.00e-154	537.00
IUUC-Tni-120140	Tetraodon nigroviridis	59.57	7.00e-87	313.00
IUUC-Tae-124420	Triticum aestivum	32.32	4.00e-18	86.30
IUUC-Tbe-127306	Tupaia belangeri	84.54	8.00e-152	529.00
IUUC-Ttr-128923	Tursiops truncatus	83.61	6.00e-138	483.00
IUUC-Vpa-130148	Vicugna pacos	85.53	9.00e-152	529.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence