iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000010327.2	ENSMLUT00000022761.1	ENSMLUP00000016592.1
ENSMLUG00000010327.2	ENSMLUT00000010336.2	ENSMLUP00000009419.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.30e-09	35.9	14	57
E3 activity/RING/U-box	5.40e-07	29.6	10	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl+ f+  p++  CgH f++ Cl ++      + +++ CP C+
   Q: 14   CPLCLQLFDA-PVTAECGHSFCRACLSRV-AGEPGADGTAPCPSCQ 57
           ********99.999***************.5555899********7 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwl....asggktcPvtrqplteedlvPnltlrrliq 66
           +e+ Cp+ l+l+  Pv++++G+++ r+++ +      a+g   cP +++p++++ l  nl l rl++
   Q: 10   QELSCPLCLQLFDAPVTAECGHSFCRACLSRVAgepgADGTAPCPSCQAPTRPQALSTNLQLARLVE 76
           6899***************************876555555559****************99988765 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MSAAPGLLRQ ELSCPLCLQL FDAPVTAECG HSFCRACLSR VAGEPGADGT APCPSCQAPT 60
RPQALSTNLQ LARLVEGLAQ VPQGHCEEHL DPLSIYCEQD RALVCGVCAS LGSHRGHRLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGCTG CGCCCGGTCT CCTGCGCCAG GAGCTGTCCT GCCCGCTGTG TTTGCAGCTG 60
TTCGATGCGC CGGTGACAGC AGAGTGCGGC CACAGCTTCT GCCGCGCCTG CCTGAGCCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018370	Caenorhabditis elegans	37.63	3.00e-08	52.40
IUUC-Cja-018969	Callithrix jacchus	51.04	5.00e-63	234.00
IUUC-Cfa-020155	Canis familiaris	66.55	2.00e-92	333.00
IUUC-Cpo-021646	Cavia porcellus	63.76	2.00e-89	322.00
IUUC-Dno-029142	Dasypus novemcinctus	64.58	3.00e-86	312.00
IUUC-Dor-030394	Dipodomys ordii	89.76	5.00e-63	235.00
IUUC-Eca-034378	Equus caballus	65.51	4.00e-92	331.00
IUUC-Eeu-034526	Erinaceus europaeus	60.96	1.00e-81	296.00
IUUC-Fca-036440	Felis catus	65.85	1.00e-92	333.00
IUUC-Ggo-045086	Gorilla gorilla	65.85	1.00e-92	333.00
IUUC-Hsa-046533	Homo sapiens	65.85	3.00e-92	332.00
IUUC-Itr-048959	Ictidomys tridecemlineatus	64.46	2.00e-90	325.00
IUUC-Laf-054479	Loxodonta africana	64.46	7.00e-89	320.00
IUUC-Mcc-055814	Macaca mulatta	66.09	2.00e-90	326.00
IUUC-Mmr-061616	Microcebus murinus	65.85	2.00e-93	335.00
IUUC-Mdo-062252	Monodelphis domestica	56.70	1.00e-73	270.00
IUUC-Mmu-063094	Mus musculus	63.76	3.00e-90	325.00
IUUC-Nle-069476	Nomascus leucogenys	65.62	6.00e-91	327.00
IUUC-Opr-070871	Ochotona princeps	60.14	3.00e-83	302.00
IUUC-Oan-072738	Ornithorhynchus anatinus	56.12	4.00e-73	268.00
IUUC-Ocu-074132	Oryctolagus cuniculus	66.20	1.00e-93	336.00
IUUC-Olu-087666	Ostreococcus lucimarinus	41.89	9.00e-12	65.10
IUUC-Oar-089555	Ovis aries	65.05	2.00e-89	323.00
IUUC-Ptr-090792	Pan troglodytes	65.85	3.00e-92	332.00
IUUC-Pan-092897	Papio anubis	65.85	2.00e-92	332.00
IUUC-Pab-098716	Pongo abelii	65.85	2.00e-92	332.00
IUUC-Pca-100618	Procavia capensis	63.00	3.00e-67	249.00
IUUC-Pva-102430	Pteropus vampyrus	66.96	1.00e-71	263.00
IUUC-Rno-105665	Rattus norvegicus	63.41	6.00e-90	324.00
IUUC-Ssc-116124	Sus scrofa	64.81	4.00e-89	321.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence