iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	7.70e-06	26.3	7	76
E3 activity/RING/RING	7.90e-11	42.7	9	58

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 6    flCpIslelMrdPvvlpsGitydrssIek...wlasggk.......tcPvtrqpl.teedlvPnltlrrl 64
           f CpI le+ r+Pv+lp+G+ +  +++     + + gg+        cP++++p+ +  +l  n+tl +l
   Q: 7    FSCPICLEPLREPVTLPCGHNFCLACLGAlwpHRSAGGTggsggpaRCPLCQEPFpDGLQLRKNHTLSEL 76
           99*********************99986521155777778999999*********778899****99776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw....pglknssskefrCPlCr 46
           C+iCle++++ p++lpCgH f++ Cl   w     g    s + +rCPlC+
   Q: 9    CPICLEPLRE-PVTLPCGHNFCLACLgALWphrsAGGTGGSGGPARCPLCQ 58
           ********99.***************7667888888888899999*****7 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDGSGPFSCP ICLEPLREPV TLPCGHNFCL ACLGALWPHR SAGGTGGSGG PARCPLCQEP 60
FPDGLQLRKN HTLSELLQLR QGSSPGPMSA PAPGSARGAT PEPSAPSAPP PAPEPSAPCA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGGTAGCG GCGGAGCCAT GGACGGCAGC GGGCCTTTCA GCTGCCCCAT CTGCCTGGAA 60
CCGCTCCGGG AGCCGGTGAC ACTACCCTGC GGCCACAACT TCTGTCTCGC TTGCCTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR013320--ConA-like_dom
IPR006574--PRY
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00643--zf-B_box

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding

KEGG

rno:690374

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001364	Ailuropoda melanoleuca	88.64	0.00e+00	749.00
IUUC-Aca-005308	Anolis carolinensis	53.58	4.00e-101	361.00
IUUC-Bta-013256	Bos taurus	91.09	0.00e+00	753.00
IUUC-Cja-018778	Callithrix jacchus	80.53	0.00e+00	844.00
IUUC-Cfa-020705	Canis familiaris	89.82	1.00e-98	353.00
IUUC-Cpo-021797	Cavia porcellus	85.36	0.00e+00	906.00
IUUC-Csa-023409	Chlorocebus sabaeus	87.07	0.00e+00	900.00
IUUC-Dor-030726	Dipodomys ordii	91.28	0.00e+00	973.00
IUUC-Eca-033641	Equus caballus	89.61	6.00e-178	616.00
IUUC-Eeu-034657	Erinaceus europaeus	86.32	4.00e-102	364.00
IUUC-Fca-036282	Felis catus	71.03	0.00e+00	684.00
IUUC-Fal-036823	Ficedula albicollis	56.22	7.00e-120	423.00
IUUC-Gga-040334	Gallus gallus	55.30	8.00e-119	420.00
IUUC-Ggo-044515	Gorilla gorilla	87.23	0.00e+00	910.00
IUUC-Hsa-046469	Homo sapiens	89.41	0.00e+00	932.00
IUUC-Itr-048949	Ictidomys tridecemlineatus	76.48	0.00e+00	805.00
IUUC-Laf-054448	Loxodonta africana	83.80	0.00e+00	932.00
IUUC-Mcc-054916	Macaca mulatta	87.69	0.00e+00	901.00
IUUC-Meu-056438	Macropus eugenii	77.73	0.00e+00	919.00
IUUC-Mga-059813	Meleagris gallopavo	54.14	8.00e-137	479.00
IUUC-Mmr-060614	Microcebus murinus	84.42	0.00e+00	896.00
IUUC-Mdo-062464	Monodelphis domestica	78.30	0.00e+00	840.00
IUUC-Mmu-063631	Mus musculus	96.42	0.00e+00	1056.00
IUUC-Mpu-066154	Mustela putorius furo	90.00	3.00e-178	617.00
IUUC-Mlu-067203	Myotis lucifugus	89.71	0.00e+00	704.00
IUUC-Nle-069591	Nomascus leucogenys	90.10	0.00e+00	668.00
IUUC-Opr-070649	Ochotona princeps	91.21	0.00e+00	790.00
IUUC-Oan-073653	Ornithorhynchus anatinus	78.54	5.00e-101	361.00
IUUC-Ocu-074752	Oryctolagus cuniculus	88.08	0.00e+00	864.00
IUUC-Oga-088971	Otolemur garnettii	86.92	0.00e+00	953.00
IUUC-Oar-089868	Ovis aries	75.46	1.00e-140	492.00
IUUC-Ptr-091634	Pan troglodytes	89.56	0.00e+00	919.00
IUUC-Pan-092126	Papio anubis	86.60	0.00e+00	901.00
IUUC-Psi-093955	Pelodiscus sinensis	56.85	5.00e-109	387.00
IUUC-Pab-097985	Pongo abelii	87.38	0.00e+00	889.00
IUUC-Pva-102360	Pteropus vampyrus	81.78	0.00e+00	804.00
IUUC-Sha-107613	Sarcophilus harrisii	80.10	1.00e-172	599.00
IUUC-Ssc-116292	Sus scrofa	88.65	0.00e+00	801.00
IUUC-Tgu-116986	Taeniopygia guttata	53.71	4.00e-148	518.00
IUUC-Tbe-127869	Tupaia belangeri	78.16	3.00e-165	574.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence