iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005136

UUCD1 version

UUC-AnC-00540

Ensembl Protein ID

ENSACAP00000004697.3

UniProt Accession

G1KD72; G1KD72_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000004814.3	ENSACAT00000004804.3	ENSACAP00000004697.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.40e-19	69.4	62	125
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.50e-09	35.0	161	192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv+l+vg   f++h++vLaa+S +F+a+f ++l+e+  +++++ik+v++e ++ ll++ Yt+k+
   Q: 62   TDVTLCVGSMSFSCHRVVLAAASNYFRAMFCNDLKEKY-EEKIVIKGVDAETMQILLDYTYTSKV 125
           7***********************************97.***********************997 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +eNc+gilr+Ad+++++ Lk+ + ++i+++F+
   Q: 161  PENCVGILRLADTHSLEALKQHVKSYIIQNFT 192
           89*****************************7 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MGDMVKENLE EEPPLPLENE GSKTRGELVE VSINERVKFD DTGLSMVLQN GLENLRLENS 60
LTDVTLCVGS MSFSCHRVVL AAASNYFRAM FCNDLKEKYE EKIVIKGVDA ETMQILLDYT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCATATTCAA GGATGTCTTA AAAGCTTGCA GGTTTGAAAC AACAATAACA ACAACCCATC 60
GGCCTTTCTT TGTACGGACA GGATGAGAAA GTGCAAGGCT TCCTGTTATG TGTGTGTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR029851--KLHL6
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0000976--F:transcription regulatory region sequence-specific DNA binding
GO:0050853--P:B cell receptor signaling pathway
GO:0002467--P:germinal center formation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

acs:100552775

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001509	Ailuropoda melanoleuca	83.90	0.00e+00	1066.00
IUUC-Apl-003490	Anas platyrhynchos	85.67	0.00e+00	1077.00
IUUC-Ame-010886	Astyanax mexicanus	70.96	0.00e+00	826.00
IUUC-Bta-013473	Bos taurus	84.33	0.00e+00	1037.00
IUUC-Cja-018888	Callithrix jacchus	83.73	0.00e+00	1061.00
IUUC-Cpo-021761	Cavia porcellus	76.82	0.00e+00	960.00
IUUC-Csa-023206	Chlorocebus sabaeus	84.07	0.00e+00	1066.00
IUUC-Cin-025367	Ciona intestinalis	41.34	4.00e-133	468.00
IUUC-Csv-026076	Ciona savignyi	42.37	2.00e-130	459.00
IUUC-Dre-027948	Danio rerio	74.43	0.00e+00	916.00
IUUC-Dno-030045	Dasypus novemcinctus	83.56	0.00e+00	1061.00
IUUC-Dor-030839	Dipodomys ordii	77.63	0.00e+00	950.00
IUUC-Eca-033608	Equus caballus	84.75	0.00e+00	1051.00
IUUC-Eeu-034640	Erinaceus europaeus	83.70	0.00e+00	1065.00
IUUC-Fca-036065	Felis catus	83.59	0.00e+00	1063.00
IUUC-Fal-036949	Ficedula albicollis	85.42	0.00e+00	1081.00
IUUC-Gmo-039661	Gadus morhua	60.97	7.00e-174	603.00
IUUC-Gga-040740	Gallus gallus	85.25	0.00e+00	1077.00
IUUC-Gac-042413	Gasterosteus aculeatus	62.30	0.00e+00	753.00
IUUC-Ggo-045167	Gorilla gorilla	82.16	0.00e+00	1064.00
IUUC-Hsa-046120	Homo sapiens	82.16	0.00e+00	1065.00
IUUC-Itr-047926	Ictidomys tridecemlineatus	81.83	0.00e+00	1059.00
IUUC-Lch-049709	Latimeria chalumnae	81.40	0.00e+00	1025.00
IUUC-Loc-052239	Lepisosteus oculatus	80.61	0.00e+00	963.00
IUUC-Laf-054511	Loxodonta africana	83.25	0.00e+00	1063.00
IUUC-Mcc-055109	Macaca mulatta	84.07	0.00e+00	1066.00
IUUC-Mga-060012	Meleagris gallopavo	81.67	0.00e+00	1053.00
IUUC-Mmr-061364	Microcebus murinus	83.56	0.00e+00	1059.00
IUUC-Mdo-063033	Monodelphis domestica	77.48	0.00e+00	926.00
IUUC-Mmu-063880	Mus musculus	83.42	0.00e+00	1032.00
IUUC-Mlu-068233	Myotis lucifugus	84.07	0.00e+00	1067.00
IUUC-Opr-070638	Ochotona princeps	83.81	0.00e+00	749.00
IUUC-Ont-071960	Oreochromis niloticus	63.59	0.00e+00	768.00
IUUC-Oan-073406	Ornithorhynchus anatinus	78.64	0.00e+00	983.00
IUUC-Ocu-074612	Oryctolagus cuniculus	83.76	0.00e+00	1062.00
IUUC-Ola-087181	Oryzias latipes	63.43	0.00e+00	763.00
IUUC-Oga-088955	Otolemur garnettii	83.56	0.00e+00	1058.00
IUUC-Oar-089682	Ovis aries	84.50	0.00e+00	1038.00
IUUC-Ptr-090969	Pan troglodytes	82.16	0.00e+00	1065.00
IUUC-Pan-092289	Papio anubis	84.07	0.00e+00	1066.00
IUUC-Psi-093279	Pelodiscus sinensis	85.76	0.00e+00	1082.00
IUUC-Pab-097957	Pongo abelii	84.65	0.00e+00	827.00
IUUC-Pca-100619	Procavia capensis	81.69	0.00e+00	1052.00
IUUC-Pva-102533	Pteropus vampyrus	82.91	1.00e-173	602.00
IUUC-Rno-106111	Rattus norvegicus	82.91	0.00e+00	1058.00
IUUC-Sha-106716	Sarcophilus harrisii	77.80	0.00e+00	971.00
IUUC-Tgu-116839	Taeniopygia guttata	85.42	0.00e+00	1079.00
IUUC-Tru-117792	Takifugu rubripes	63.11	0.00e+00	753.00
IUUC-Tsy-119609	Tarsius syrichta	75.37	7.00e-122	430.00
IUUC-Tni-119682	Tetraodon nigroviridis	62.85	0.00e+00	754.00
IUUC-Tme-127039	Tuber melanosporum	31.13	5.00e-14	73.60
IUUC-Tbe-127961	Tupaia belangeri	78.31	0.00e+00	953.00
IUUC-Ttr-128917	Tursiops truncatus	83.27	0.00e+00	873.00
IUUC-Vpa-130721	Vicugna pacos	84.87	0.00e+00	768.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence