iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048820

Ensembl Protein ID

ENSSTOP00000023556.1

UniProt Accession

I3NGQ9; I3NGQ9_ICTTR

Genbank Protein ID

ENSSTOP00000023556

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01083016

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000027038.1	ENSSTOT00000026799.1	ENSSTOP00000023556.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	94.97	4.00e-164	575.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

LRMAGCGEID HSINMLPTNR KANESCSNTA PSLTVPECAI CLQTCVHPVS LPCKHVFCYL 60
CVKGASWLGK RCALCRQEIP EDFLDKPTLL SPEELKAASR GNGEYAWYYE GRNGWWQYDE 120

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Nucleotide Sequence
(Fasta)

CTTAGGATGG CTGGCTGTGG TGAGATTGAT CACTCAATAA ACATGCTTCC TACGAACAGG 60
AAAGCGAATG AGTCCTGTTC TAATACTGCA CCTTCTCTAA CTGTTCCTGA ATGTGCCATT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	92.22	5.00e-150	523.00
IUUC-Apl-004143	Anas platyrhynchos	79.21	6.00e-133	466.00
IUUC-Aca-004557	Anolis carolinensis	76.88	2.00e-127	448.00
IUUC-Ame-011088	Astyanax mexicanus	60.31	5.00e-83	300.00
IUUC-Bta-012639	Bos taurus	92.68	8.00e-149	519.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	5.00e-19	87.40
IUUC-Cja-019397	Callithrix jacchus	95.53	1.00e-155	542.00
IUUC-Cfa-021140	Canis familiaris	90.22	1.00e-160	558.00
IUUC-Cpo-021387	Cavia porcellus	92.39	3.00e-172	597.00
IUUC-Csa-023503	Chlorocebus sabaeus	91.33	2.00e-152	531.00
IUUC-Cho-024895	Choloepus hoffmanni	89.80	1.00e-135	475.00
IUUC-Cin-025455	Ciona intestinalis	51.92	4.00e-43	167.00
IUUC-Dre-028824	Danio rerio	46.35	5.00e-82	297.00
IUUC-Dno-029269	Dasypus novemcinctus	92.78	3.00e-155	540.00
IUUC-Dor-030592	Dipodomys ordii	94.96	2.00e-164	571.00
IUUC-Dme-031618	Drosophila melanogaster	57.33	1.00e-55	210.00
IUUC-Ete-032478	Echinops telfairi	91.85	8.00e-161	559.00
IUUC-Eca-033389	Equus caballus	95.49	3.00e-178	617.00
IUUC-Fca-035488	Felis catus	94.94	2.00e-161	561.00
IUUC-Fal-037087	Ficedula albicollis	78.27	1.00e-150	525.00
IUUC-Gga-040401	Gallus gallus	85.43	8.00e-136	476.00
IUUC-Gac-042412	Gasterosteus aculeatus	64.55	2.00e-87	315.00
IUUC-Ggo-045417	Gorilla gorilla	95.33	3.00e-150	524.00
IUUC-Hsa-045790	Homo sapiens	95.25	6.00e-155	539.00
IUUC-Lch-049493	Latimeria chalumnae	70.95	1.00e-113	402.00
IUUC-Loc-052927	Lepisosteus oculatus	59.08	9.00e-102	362.00
IUUC-Laf-053904	Loxodonta africana	92.80	1.00e-157	548.00
IUUC-Mcc-055427	Macaca mulatta	91.09	3.00e-156	543.00
IUUC-Mmr-060580	Microcebus murinus	95.52	2.00e-155	541.00
IUUC-Mdo-062094	Monodelphis domestica	96.95	5.00e-78	281.00
IUUC-Mmu-063363	Mus musculus	93.31	4.00e-166	577.00
IUUC-Mpu-066816	Mustela putorius furo	92.50	9.00e-152	529.00
IUUC-Mlu-067433	Myotis lucifugus	91.94	8.00e-172	595.00
IUUC-Nle-068986	Nomascus leucogenys	94.69	9.00e-169	585.00
IUUC-Ont-072670	Oreochromis niloticus	64.63	1.00e-79	290.00
IUUC-Oan-073330	Ornithorhynchus anatinus	87.06	3.00e-107	380.00
IUUC-Ocu-074161	Oryctolagus cuniculus	94.35	6.00e-166	576.00
IUUC-Ola-086902	Oryzias latipes	59.49	6.00e-84	303.00
IUUC-Oga-089159	Otolemur garnettii	92.68	9.00e-178	615.00
IUUC-Oar-089586	Ovis aries	93.24	1.00e-144	505.00
IUUC-Ptr-090987	Pan troglodytes	95.25	6.00e-155	539.00
IUUC-Pan-091867	Papio anubis	91.11	1.00e-156	545.00
IUUC-Psi-094024	Pelodiscus sinensis	84.36	7.00e-139	486.00
IUUC-Pma-094453	Petromyzon marinus	63.31	1.00e-64	239.00
IUUC-Pfo-097108	Poecilia formosa	52.34	8.00e-85	306.00
IUUC-Pab-097997	Pongo abelii	93.30	8.00e-161	559.00
IUUC-Pca-100260	Procavia capensis	90.99	2.00e-161	560.00
IUUC-Pva-103140	Pteropus vampyrus	92.20	1.00e-159	555.00
IUUC-Rno-105795	Rattus norvegicus	91.53	5.00e-164	569.00
IUUC-Sha-107033	Sarcophilus harrisii	88.55	1.00e-153	535.00
IUUC-Ssc-116395	Sus scrofa	93.89	1.00e-174	605.00
IUUC-Tgu-116685	Taeniopygia guttata	77.37	1.00e-132	465.00
IUUC-Tru-118014	Takifugu rubripes	64.45	2.00e-84	304.00
IUUC-Tsy-119326	Tarsius syrichta	86.63	1.00e-166	578.00
IUUC-Tni-120322	Tetraodon nigroviridis	69.95	7.00e-82	296.00
IUUC-Tbe-128067	Tupaia belangeri	94.15	2.00e-164	570.00
IUUC-Ttr-128530	Tursiops truncatus	94.43	5.00e-158	550.00
IUUC-Vpa-130322	Vicugna pacos	94.69	8.00e-165	572.00
IUUC-Xtr-132606	Xenopus tropicalis	67.23	7.00e-118	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence