iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011257

Ensembl Protein ID

ENSAMXP00000014523.1

UniProt Accession

W5L3W1; W5L3W1_ASTMX

Genbank Protein ID

ENSAMXP00000014523

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

APWO01014395

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000014106.1	ENSAMXT00000014523.1	ENSAMXP00000014523.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.30e-17	61.5	69	125

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + v++ly+yea ++d+L +kkG++++v+   e+ ++W+k+++  + k+G++P+n+v++++
   Q: 69   KIVIALYPYEAIHTDDLGFKKGEKLRVL---EEHGEWWKAKSLSTRKEGFIPSNYVAQAD 125
           5799************************...999**********************9986 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MGCKKSKLDD GQNGGMLGVK RRESPRTEKT VYVRDPTSPK PHTINNSPPP GLLPGQMFQK 60
MEEQSEPGKI VIALYPYEAI HTDDLGFKKG EKLRVLEEHG EWWKAKSLST RKEGFIPSNY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAATGCAGT GCGGGTAGCA GCAGGAAGTA GCTGCAGGTT CCTCTTTCTG TCTGTCTGTC 60
CAGCTCACTT CAATGAGTCT CGCGACCACA GGCGAGAGAG AGAGAGCAGC GCGCGCTCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0090022--P:regulation of neutrophil chemotaxis
GO:0009611--P:response to wounding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001812	Ailuropoda melanoleuca	75.92	0.00e+00	817.00
IUUC-Apl-004139	Anas platyrhynchos	77.46	0.00e+00	828.00
IUUC-Aca-004333	Anolis carolinensis	77.13	0.00e+00	824.00
IUUC-Bta-013257	Bos taurus	76.16	0.00e+00	819.00
IUUC-Cja-018827	Callithrix jacchus	76.16	0.00e+00	819.00
IUUC-Cfa-020816	Canis familiaris	75.97	0.00e+00	817.00
IUUC-Cpo-021423	Cavia porcellus	77.13	0.00e+00	829.00
IUUC-Csa-024244	Chlorocebus sabaeus	76.31	0.00e+00	818.00
IUUC-Dre-028518	Danio rerio	86.02	0.00e+00	923.00
IUUC-Dno-029322	Dasypus novemcinctus	76.70	0.00e+00	823.00
IUUC-Dor-030706	Dipodomys ordii	68.74	0.00e+00	723.00
IUUC-Eca-034193	Equus caballus	76.16	0.00e+00	824.00
IUUC-Fal-037273	Ficedula albicollis	77.86	0.00e+00	837.00
IUUC-Gmo-039677	Gadus morhua	82.30	0.00e+00	791.00
IUUC-Gga-040417	Gallus gallus	76.12	0.00e+00	812.00
IUUC-Gac-042490	Gasterosteus aculeatus	80.00	0.00e+00	875.00
IUUC-Ggo-045096	Gorilla gorilla	76.31	0.00e+00	820.00
IUUC-Hsa-046214	Homo sapiens	76.31	0.00e+00	820.00
IUUC-Itr-048354	Ictidomys tridecemlineatus	76.50	0.00e+00	824.00
IUUC-Lch-049991	Latimeria chalumnae	77.37	0.00e+00	820.00
IUUC-Loc-052309	Lepisosteus oculatus	87.40	0.00e+00	940.00
IUUC-Laf-053568	Loxodonta africana	75.78	0.00e+00	816.00
IUUC-Mcc-054849	Macaca mulatta	76.31	0.00e+00	818.00
IUUC-Meu-056170	Macropus eugenii	68.87	0.00e+00	655.00
IUUC-Mmr-061519	Microcebus murinus	76.12	0.00e+00	822.00
IUUC-Mdo-062090	Monodelphis domestica	76.08	0.00e+00	762.00
IUUC-Mmu-063760	Mus musculus	76.31	0.00e+00	821.00
IUUC-Mpu-065677	Mustela putorius furo	76.50	0.00e+00	823.00
IUUC-Mlu-067386	Myotis lucifugus	76.31	0.00e+00	822.00
IUUC-Nle-069742	Nomascus leucogenys	76.50	0.00e+00	822.00
IUUC-Ont-071537	Oreochromis niloticus	82.36	0.00e+00	893.00
IUUC-Oan-073193	Ornithorhynchus anatinus	76.89	0.00e+00	829.00
IUUC-Ocu-074501	Oryctolagus cuniculus	76.36	0.00e+00	823.00
IUUC-Ola-086726	Oryzias latipes	79.22	0.00e+00	863.00
IUUC-Oga-088069	Otolemur garnettii	74.85	0.00e+00	811.00
IUUC-Oar-090091	Ovis aries	76.31	0.00e+00	822.00
IUUC-Ptr-091409	Pan troglodytes	76.31	0.00e+00	820.00
IUUC-Pan-092268	Papio anubis	76.31	0.00e+00	820.00
IUUC-Psi-093685	Pelodiscus sinensis	77.84	0.00e+00	836.00
IUUC-Pfo-096217	Poecilia formosa	79.42	0.00e+00	871.00
IUUC-Pab-098601	Pongo abelii	76.50	0.00e+00	822.00
IUUC-Rno-105557	Rattus norvegicus	76.31	0.00e+00	822.00
IUUC-Sha-106643	Sarcophilus harrisii	75.34	0.00e+00	808.00
IUUC-Ssc-116317	Sus scrofa	70.99	0.00e+00	753.00
IUUC-Tgu-116865	Taeniopygia guttata	78.14	0.00e+00	839.00
IUUC-Tru-118284	Takifugu rubripes	77.99	0.00e+00	845.00
IUUC-Tsy-119440	Tarsius syrichta	73.79	0.00e+00	788.00
IUUC-Tni-120005	Tetraodon nigroviridis	78.06	0.00e+00	854.00
IUUC-Ttr-128481	Tursiops truncatus	71.55	0.00e+00	678.00
IUUC-Xtr-131907	Xenopus tropicalis	70.19	0.00e+00	732.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence