iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096217

Ensembl Protein ID

ENSPFOP00000014091.2

UniProt Accession

A0A087Y7T8; A0A087Y7T8_POEFO

Genbank Protein ID

ENSPFOP00000014091

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AYCK01014255

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000014008.2	ENSPFOT00000014110.2	ENSPFOP00000014091.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.50e-17	61.4	63	119

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++v+ ly+yea ++d+L +kkG++++++   e+ ++W+k+++ +++k+G++P+n+v++++
   Q: 63   KVVIGLYPYEALHQDDLGFKKGEKMKIL---EEHGDWWKAKSLTSNKEGFIPSNYVAQVD 119
           78999***********************...999***********************997 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MGCLKSTLSG GLASGVESKI RQQAQKPEPA HYVRDPTFNT NRNNSLLPGQ RFQQMEEKES 60
TLKVVIGLYP YEALHQDDLG FKKGEKMKIL EEHGDWWKAK SLTSNKEGFI PSNYVAQVDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGTACCAG GAAGTTTGGG TAAGATAGAA AAATCCCCAA GCAGCTACTC TGAGTTCCTC 60
ATTCTGCCGT AGCTGTCCAC GACGGCCATG TGACCCTCTT GTCATGCCGT GTGTGTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0090022--P:regulation of neutrophil chemotaxis
GO:0009611--P:response to wounding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001812	Ailuropoda melanoleuca	71.79	0.00e+00	786.00
IUUC-Apl-004139	Anas platyrhynchos	72.64	0.00e+00	788.00
IUUC-Aca-004333	Anolis carolinensis	73.93	0.00e+00	802.00
IUUC-Ame-011257	Astyanax mexicanus	79.42	0.00e+00	871.00
IUUC-Bta-013257	Bos taurus	71.98	0.00e+00	789.00
IUUC-Cja-018827	Callithrix jacchus	72.57	0.00e+00	790.00
IUUC-Cfa-020816	Canis familiaris	71.60	0.00e+00	784.00
IUUC-Cpo-021423	Cavia porcellus	72.18	0.00e+00	791.00
IUUC-Csa-024244	Chlorocebus sabaeus	72.18	0.00e+00	787.00
IUUC-Dre-028518	Danio rerio	80.70	0.00e+00	874.00
IUUC-Dno-029322	Dasypus novemcinctus	72.37	0.00e+00	791.00
IUUC-Dor-030706	Dipodomys ordii	65.88	0.00e+00	704.00
IUUC-Eca-034193	Equus caballus	72.18	0.00e+00	793.00
IUUC-Fal-037273	Ficedula albicollis	73.01	0.00e+00	798.00
IUUC-Gmo-039677	Gadus morhua	81.21	0.00e+00	777.00
IUUC-Gga-040417	Gallus gallus	73.33	0.00e+00	788.00
IUUC-Gac-042490	Gasterosteus aculeatus	81.68	0.00e+00	890.00
IUUC-Ggo-045096	Gorilla gorilla	72.18	0.00e+00	789.00
IUUC-Hsa-046214	Homo sapiens	72.18	0.00e+00	789.00
IUUC-Itr-048354	Ictidomys tridecemlineatus	71.98	0.00e+00	790.00
IUUC-Lch-049991	Latimeria chalumnae	74.42	0.00e+00	795.00
IUUC-Loc-052309	Lepisosteus oculatus	79.84	0.00e+00	880.00
IUUC-Laf-053568	Loxodonta africana	72.37	0.00e+00	791.00
IUUC-Mcc-054849	Macaca mulatta	72.18	0.00e+00	787.00
IUUC-Mmr-061519	Microcebus murinus	71.40	0.00e+00	785.00
IUUC-Mdo-062090	Monodelphis domestica	67.25	0.00e+00	741.00
IUUC-Mmu-063760	Mus musculus	72.71	0.00e+00	793.00
IUUC-Mpu-065677	Mustela putorius furo	72.37	0.00e+00	791.00
IUUC-Mlu-067386	Myotis lucifugus	72.18	0.00e+00	790.00
IUUC-Nle-069742	Nomascus leucogenys	72.18	0.00e+00	788.00
IUUC-Ont-071537	Oreochromis niloticus	85.91	0.00e+00	933.00
IUUC-Oan-073193	Ornithorhynchus anatinus	72.09	0.00e+00	795.00
IUUC-Ocu-074501	Oryctolagus cuniculus	72.57	0.00e+00	792.00
IUUC-Ola-086726	Oryzias latipes	81.87	0.00e+00	902.00
IUUC-Oga-088069	Otolemur garnettii	71.51	0.00e+00	782.00
IUUC-Oar-090091	Ovis aries	71.98	0.00e+00	788.00
IUUC-Ptr-091409	Pan troglodytes	72.18	0.00e+00	789.00
IUUC-Pan-092268	Papio anubis	72.18	0.00e+00	788.00
IUUC-Psi-093685	Pelodiscus sinensis	73.55	0.00e+00	803.00
IUUC-Pab-098601	Pongo abelii	72.18	0.00e+00	788.00
IUUC-Rno-105557	Rattus norvegicus	73.15	0.00e+00	796.00
IUUC-Sha-106643	Sarcophilus harrisii	72.09	0.00e+00	782.00
IUUC-Ssc-116317	Sus scrofa	67.57	0.00e+00	725.00
IUUC-Tgu-116865	Taeniopygia guttata	73.40	0.00e+00	802.00
IUUC-Tru-118284	Takifugu rubripes	80.93	0.00e+00	884.00
IUUC-Tsy-119440	Tarsius syrichta	75.54	0.00e+00	765.00
IUUC-Tni-120005	Tetraodon nigroviridis	80.82	0.00e+00	883.00
IUUC-Ttr-128481	Tursiops truncatus	63.53	0.00e+00	659.00
IUUC-Xtr-131907	Xenopus tropicalis	65.57	0.00e+00	695.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence